DK3983387T3 - Sulfonylurinstofderivater og anvendelser deraf - Google Patents
Sulfonylurinstofderivater og anvendelser deraf Download PDFInfo
- Publication number
- DK3983387T3 DK3983387T3 DK20733706.4T DK20733706T DK3983387T3 DK 3983387 T3 DK3983387 T3 DK 3983387T3 DK 20733706 T DK20733706 T DK 20733706T DK 3983387 T3 DK3983387 T3 DK 3983387T3
- Authority
- DK
- Denmark
- Prior art keywords
- sulfonylurea derivatives
- sulfonylurea
- derivatives
- Prior art date
Links
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962860663P | 2019-06-12 | 2019-06-12 | |
| PCT/EP2020/066191 WO2020249667A1 (en) | 2019-06-12 | 2020-06-11 | Sulfonylurea derivatives and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3983387T3 true DK3983387T3 (da) | 2024-07-15 |
Family
ID=71108563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20733706.4T DK3983387T3 (da) | 2019-06-12 | 2020-06-11 | Sulfonylurinstofderivater og anvendelser deraf |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US12054461B2 (https=) |
| EP (1) | EP3983387B1 (https=) |
| JP (1) | JP7682813B2 (https=) |
| CN (1) | CN114641466B (https=) |
| DK (1) | DK3983387T3 (https=) |
| ES (1) | ES2983661T3 (https=) |
| FI (1) | FI3983387T3 (https=) |
| HR (1) | HRP20240896T1 (https=) |
| HU (1) | HUE067378T2 (https=) |
| LT (1) | LT3983387T (https=) |
| PL (1) | PL3983387T3 (https=) |
| PT (1) | PT3983387T (https=) |
| RS (1) | RS65711B1 (https=) |
| SI (1) | SI3983387T1 (https=) |
| SM (1) | SMT202400291T1 (https=) |
| WO (1) | WO2020249667A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| PL3983387T3 (pl) | 2019-06-12 | 2024-08-19 | NodThera Limited | Pochodne sulfonylomocznika i ich zastosowania |
| KR102802013B1 (ko) * | 2021-02-03 | 2025-05-07 | 환인제약 주식회사 | 알츠하이머병 치료를 위한 nlrp3 인플라마좀 소분자 억제제 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2110689A (en) | 1981-12-03 | 1983-06-22 | Sandoz Ltd | Herbicidal heterocyclic aminosulfonyl ureas and isoureas |
| CH649081A5 (de) | 1982-01-12 | 1985-04-30 | Ciba Geigy Ag | Triaza-verbindungen. |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| JPS60214785A (ja) * | 1984-03-27 | 1985-10-28 | Nissan Chem Ind Ltd | ピラゾ−ルスルホニルウレア誘導体、および植物生長調節剤または除草剤 |
| US5214206A (en) | 1990-11-07 | 1993-05-25 | Warner-Lambert Company | Aminosulfonyl urea acat inhibitors |
| CA2115990A1 (en) | 1991-08-19 | 1993-03-04 | George Albert Boswell | Angiotensin ii receptor blocking imidazolinone derivatives |
| WO1993004045A1 (en) | 1991-08-19 | 1993-03-04 | E.I. Du Pont De Nemours And Company | Angiotensin ii receptor blocking imidazolinone derivatives |
| NZ247440A (en) | 1992-05-06 | 1995-04-27 | Squibb & Sons Inc | Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof |
| DE4217719A1 (de) * | 1992-05-29 | 1993-12-02 | Bayer Ag | Zweifach heterocyclisch substituierte Sulfonylamino(thio)carbonylverbindungen |
| DE4302701A1 (de) | 1993-02-01 | 1994-08-04 | Bayer Ag | Arylaminosulfonylharnstoffe |
| DE4302702A1 (de) | 1993-02-01 | 1994-08-04 | Bayer Ag | Arylaminosulfonylharnstoffe |
| JP3355237B2 (ja) | 1993-10-15 | 2002-12-09 | 呉羽化学工業株式会社 | Ｎ−（置換アミノ）ピロール誘導体、その製造方法及び除草剤 |
| JPH0827147A (ja) * | 1994-07-20 | 1996-01-30 | Kureha Chem Ind Co Ltd | Ｎ−（置換アミノ）イミド誘導体、その製造方法及び除草剤 |
| JPH09132574A (ja) | 1995-11-09 | 1997-05-20 | Nissan Chem Ind Ltd | フルオロプロピルチアゾリン誘導体の製造法 |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| US6028201A (en) | 1996-01-30 | 2000-02-22 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| AU3440597A (en) | 1996-07-02 | 1998-01-21 | Novartis Ag | N-phenylimino heterocyclic derivatives and their use as herbicides |
| JPH1029990A (ja) | 1996-07-12 | 1998-02-03 | Kureha Chem Ind Co Ltd | １−（置換アミノ）イミダゾール誘導体、その製造方法及び除草剤 |
| DE19651037A1 (de) | 1996-12-09 | 1998-06-10 | Bayer Ag | Substituierte Thienyl(amino)sulfonyl(thio)harnstoffe |
| PT1270565E (pt) | 1997-01-29 | 2004-09-30 | Pfizer | Furano-2-sulfonamida 4-substituida e sua utilizacao na preparacao de derivados de sulfonilureia |
| IT1290062B1 (it) | 1997-03-13 | 1998-10-19 | Isagro Ricerca Srl | Amminosolfoniluree ad attivita' erbicida |
| GB9909409D0 (en) | 1999-04-24 | 1999-06-23 | Zeneca Ltd | Chemical compounds |
| DE19937118A1 (de) | 1999-08-06 | 2001-02-08 | Bayer Ag | Substituierte Thienyl(amino)sulfonylharnstoffe |
| JP4112127B2 (ja) | 1999-08-31 | 2008-07-02 | 株式会社リコー | 感熱記録材料 |
| AU7447500A (en) | 1999-09-30 | 2001-04-30 | Mitsubishi Chemical Corporation | Acylsulfonamide derivatives |
| US6593356B2 (en) | 1999-10-20 | 2003-07-15 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
| EP1281399A3 (en) | 2001-08-01 | 2004-02-11 | Warner-Lambert Company | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production |
| WO2003029226A1 (en) | 2001-09-26 | 2003-04-10 | Basf Aktiengesellschaft | Heterocyclyl substituted phenoxyalkyl-, phenylthioalkyl-, phenylaminoalkyl- and phenylalkyl-sulfamoylcarboxamides |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| AU2005325676A1 (en) | 2004-12-23 | 2006-08-03 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| CA2709784A1 (en) | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| WO2013119040A1 (en) | 2012-02-07 | 2013-08-15 | Kainos Medicine, Inc. | Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme |
| CN103288750A (zh) | 2013-03-04 | 2013-09-11 | 盐城工学院 | 新型氨基磺酰脲类化合物 |
| US9410217B2 (en) | 2014-02-18 | 2016-08-09 | Renmatix, Inc. | Method of reducing a fermentation and/or enzyme inhibitor in a saccharide-containing composition |
| SI3259253T1 (sl) | 2015-02-16 | 2020-07-31 | The University Of Queensland | Sulfonilsečnine in sorodne spojine ter njihova uporaba |
| JP2019512009A (ja) | 2016-02-16 | 2019-05-09 | ザ・ユニバーシティ・オブ・クイーンズランド | スルホニルウレアおよび関連化合物ならびにこれらの利用 |
| US10080741B2 (en) | 2016-04-26 | 2018-09-25 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as FXR agonists and methods of use thereof |
| WO2017189663A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| WO2017189651A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| WO2017201150A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | Isoxazole analogs as fxr agonists and methods of use thereof |
| WO2017201155A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | lSOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF |
| WO2017201152A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| EP3272739A1 (en) * | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| ES2988798T3 (es) | 2017-07-24 | 2024-11-21 | Novartis Ag | Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP |
| MA49903A (fr) | 2017-08-15 | 2020-06-24 | Inflazome Ltd | Sulfonylureés et sulfonylthioureés en tant qu'inhibiteurs de nlrp3 |
| EP3668840A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| JP2020531435A (ja) * | 2017-08-15 | 2020-11-05 | インフレイゾーム リミテッド | 新規なスルホンアミドカルボキサミド化合物 |
| UY37848A (es) | 2017-08-15 | 2019-03-29 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3 |
| US20210122739A1 (en) | 2017-08-15 | 2021-04-29 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| EP3668843A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
| EP3668601A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| GB201721185D0 (en) * | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| GB201902327D0 (en) * | 2019-02-20 | 2019-04-03 | Inflazome Ltd | Novel compounds |
| KR20210053910A (ko) * | 2018-08-15 | 2021-05-12 | 인플라좀 리미티드 | 신규한 설폰아마이드유레아 화합물 |
| PL3983387T3 (pl) | 2019-06-12 | 2024-08-19 | NodThera Limited | Pochodne sulfonylomocznika i ich zastosowania |
| EP3983388A1 (en) | 2019-06-12 | 2022-04-20 | Nodthera Limited | Sulfonamide derivatives and uses thereof |
| JP7661248B2 (ja) | 2019-06-12 | 2025-04-14 | ノッドセラ リミテッド | スルホニル尿素誘導体及びその使用 |
| IL301055A (en) | 2020-09-04 | 2023-05-01 | Nodthera Ltd | Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof |
-
2020
- 2020-06-11 PL PL20733706.4T patent/PL3983387T3/pl unknown
- 2020-06-11 CN CN202080057162.2A patent/CN114641466B/zh active Active
- 2020-06-11 ES ES20733706T patent/ES2983661T3/es active Active
- 2020-06-11 SM SM20240291T patent/SMT202400291T1/it unknown
- 2020-06-11 PT PT207337064T patent/PT3983387T/pt unknown
- 2020-06-11 EP EP20733706.4A patent/EP3983387B1/en active Active
- 2020-06-11 WO PCT/EP2020/066191 patent/WO2020249667A1/en not_active Ceased
- 2020-06-11 LT LTEPPCT/EP2020/066191T patent/LT3983387T/lt unknown
- 2020-06-11 RS RS20240765A patent/RS65711B1/sr unknown
- 2020-06-11 DK DK20733706.4T patent/DK3983387T3/da active
- 2020-06-11 US US17/618,184 patent/US12054461B2/en active Active
- 2020-06-11 HU HUE20733706A patent/HUE067378T2/hu unknown
- 2020-06-11 JP JP2021573382A patent/JP7682813B2/ja active Active
- 2020-06-11 FI FIEP20733706.4T patent/FI3983387T3/fi active
- 2020-06-11 SI SI202030459T patent/SI3983387T1/sl unknown
- 2020-06-11 HR HRP20240896TT patent/HRP20240896T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US12054461B2 (en) | 2024-08-06 |
| PT3983387T (pt) | 2024-07-10 |
| US20220227715A1 (en) | 2022-07-21 |
| SI3983387T1 (sl) | 2024-09-30 |
| FI3983387T3 (fi) | 2024-07-09 |
| RS65711B1 (sr) | 2024-08-30 |
| EP3983387B1 (en) | 2024-04-24 |
| PL3983387T3 (pl) | 2024-08-19 |
| SMT202400291T1 (it) | 2024-09-16 |
| CN114641466B (zh) | 2025-09-30 |
| ES2983661T3 (es) | 2024-10-24 |
| EP3983387A1 (en) | 2022-04-20 |
| JP7682813B2 (ja) | 2025-05-26 |
| HUE067378T2 (hu) | 2024-10-28 |
| HRP20240896T1 (hr) | 2024-10-11 |
| JP2022535956A (ja) | 2022-08-10 |
| CN114641466A (zh) | 2022-06-17 |
| LT3983387T (lt) | 2024-07-25 |
| WO2020249667A1 (en) | 2020-12-17 |
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