JP7645812B2 - 生物発光を使用した分析物検出のための組成物及び方法 - Google Patents

生物発光を使用した分析物検出のための組成物及び方法 Download PDF

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JP7645812B2
JP7645812B2 JP2021559761A JP2021559761A JP7645812B2 JP 7645812 B2 JP7645812 B2 JP 7645812B2 JP 2021559761 A JP2021559761 A JP 2021559761A JP 2021559761 A JP2021559761 A JP 2021559761A JP 7645812 B2 JP7645812 B2 JP 7645812B2
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target analyte
seq
analyte binding
bioluminescent
protein
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JP2022526013A (ja
JPWO2020210658A5 (enExample
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トーマス カークランド
メラニー ダート
ジヤン ゼン
トーマス スミス
キース ウッド
トーマス マクライト
エミリー ジョスト
バージニア キンケイド
フイ ワン
ウェンフイ ジョウ
ランス エンセル
メアリー ホール
ロビン ハースト
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Promega Corp
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Promega Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/103—Nucleic acid detection characterized by the use of physical, structural and functional properties luminescence

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2021559761A 2019-04-10 2020-04-10 生物発光を使用した分析物検出のための組成物及び方法 Active JP7645812B2 (ja)

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JP2025033971A JP2025133108A (ja) 2019-04-10 2025-03-04 生物発光を使用した分析物検出のための組成物及び方法

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US201962832052P 2019-04-10 2019-04-10
US62/832,052 2019-04-10
PCT/US2020/027711 WO2020210658A1 (en) 2019-04-10 2020-04-10 Compositions and methods for analyte detection using bioluminescence

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JP2022526013A JP2022526013A (ja) 2022-05-20
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US (2) US20200386748A1 (enExample)
EP (1) EP3953374A4 (enExample)
JP (2) JP7645812B2 (enExample)
KR (1) KR20220007058A (enExample)
CN (1) CN113891895A (enExample)
AU (1) AU2020272037B2 (enExample)
BR (1) BR112021020354A2 (enExample)
CA (1) CA3135195A1 (enExample)
IL (1) IL287261A (enExample)
SG (1) SG11202110773RA (enExample)
WO (1) WO2020210658A1 (enExample)

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WO2021108765A1 (en) * 2019-11-27 2021-06-03 Promega Corporation Multipartite luciferase peptides and polypeptides
WO2022241249A1 (en) * 2021-05-13 2022-11-17 Promega Corporation Bioluminescent detection of dna synthesis
WO2023028175A1 (en) * 2021-08-24 2023-03-02 Kaya17 Inc. System and method for detecting presence of a target bioparticle in a sample via a vertical flow assay
CN113786873B (zh) * 2021-08-31 2022-09-23 广西横县张一元饮品有限公司 一种用于食品安全检测的试管
JPWO2023053586A1 (enExample) * 2021-09-29 2023-04-06
CN114231401B (zh) * 2022-02-21 2022-05-03 北京芯迈微生物技术有限公司 一种核酸检测试剂盒及检测方法
WO2023200703A1 (en) * 2022-04-15 2023-10-19 Siemens Healthcare Diagnostics Inc. Creatinine lateral flow assay devices and methods of production and use thereof
GB2619059A (en) * 2022-05-26 2023-11-29 Univ Leeds Innovations Ltd Split reporter complex
WO2024129040A1 (en) * 2022-12-16 2024-06-20 T.C Ankara Universitesi Rektorlugu A card test for the hallucinogenic psilocybin molecule that allows the diagnosis of toxic mushrooms and mushroom toxicities
CN116218907B (zh) * 2023-02-20 2025-04-22 复旦大学附属中山医院 带有HiBiT新型报告基因的肠道病毒感染性克隆及其构建方法和应用
WO2024216135A1 (en) * 2023-04-12 2024-10-17 Promega Corporation Poloxamer-stabilized reagents
WO2025024530A1 (en) * 2023-07-25 2025-01-30 The General Hospital Corporation Aldehyde binding optical imaging probes methods of use thereof
CN118033130B (zh) * 2024-01-19 2024-07-30 武汉科技大学 同时检测艾滋病、梅毒和丙肝的表面、微孔板、组件、方法及应用
CN118255903B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种检测非洲猪瘟病毒抗体的融合抗原、制备方法及检测试剂盒
CN118344492B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种纳米荧光素酶融合抗原在非洲猪瘟病毒抗体检测中的应用

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US20070048807A1 (en) 2005-08-31 2007-03-01 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
JP2016500263A (ja) 2012-12-12 2016-01-12 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 細胞内生体発光共鳴エネルギ移動を用いた生物活性剤による細胞ターゲット結合の認知
JP2016519065A (ja) 2013-03-15 2016-06-30 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 構造的相補性による生物発光の活性化
WO2018148489A1 (en) 2017-02-09 2018-08-16 Promega Corporation Analyte detection immunoassay

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US20070048807A1 (en) 2005-08-31 2007-03-01 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
JP2016500263A (ja) 2012-12-12 2016-01-12 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 細胞内生体発光共鳴エネルギ移動を用いた生物活性剤による細胞ターゲット結合の認知
JP2016519065A (ja) 2013-03-15 2016-06-30 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 構造的相補性による生物発光の活性化
WO2018148489A1 (en) 2017-02-09 2018-08-16 Promega Corporation Analyte detection immunoassay

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US20200386748A1 (en) 2020-12-10
JP2022526013A (ja) 2022-05-20
AU2020272037A1 (en) 2021-12-02
KR20220007058A (ko) 2022-01-18
AU2020272037B2 (en) 2025-11-27
JP2025133108A (ja) 2025-09-10
BR112021020354A2 (pt) 2021-12-14
EP3953374A1 (en) 2022-02-16
US20250264464A1 (en) 2025-08-21
EP3953374A4 (en) 2023-06-07
CN113891895A (zh) 2022-01-04
WO2020210658A1 (en) 2020-10-15
SG11202110773RA (en) 2021-10-28
IL287261A (en) 2021-12-01
CA3135195A1 (en) 2020-10-15

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