IL287261A - Compounds and methods for detecting analytes using bioluminescence - Google Patents

Compounds and methods for detecting analytes using bioluminescence

Info

Publication number
IL287261A
IL287261A IL287261A IL28726121A IL287261A IL 287261 A IL287261 A IL 287261A IL 287261 A IL287261 A IL 287261A IL 28726121 A IL28726121 A IL 28726121A IL 287261 A IL287261 A IL 287261A
Authority
IL
Israel
Prior art keywords
bioluminescence
compositions
methods
analyte detection
analyte
Prior art date
Application number
IL287261A
Other languages
English (en)
Hebrew (he)
Inventor
Thomas Kirkland
Melanie Dart
Zhiyang Zeng
Thomas Smith
Keith Wood
Thomas Machleidt
Emily Jost
Virginia Kincaid
Wang Hui
Wenhui Zhou
Lance Encell
Mary Hall
Robin Hurst
Original Assignee
Promega Corp
Thomas Kirkland
Melanie Dart
Zhiyang Zeng
Thomas Smith
Keith Wood
Thomas Machleidt
Emily Jost
Virginia Kincaid
Wang Hui
Wenhui Zhou
Lance Encell
Mary Hall
Robin Hurst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp, Thomas Kirkland, Melanie Dart, Zhiyang Zeng, Thomas Smith, Keith Wood, Thomas Machleidt, Emily Jost, Virginia Kincaid, Wang Hui, Wenhui Zhou, Lance Encell, Mary Hall, Robin Hurst filed Critical Promega Corp
Publication of IL287261A publication Critical patent/IL287261A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y113/00Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/103Nucleic acid detection characterized by the use of physical, structural and functional properties luminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
IL287261A 2019-04-10 2021-10-07 Compounds and methods for detecting analytes using bioluminescence IL287261A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962832052P 2019-04-10 2019-04-10
PCT/US2020/027711 WO2020210658A1 (en) 2019-04-10 2020-04-10 Compositions and methods for analyte detection using bioluminescence

Publications (1)

Publication Number Publication Date
IL287261A true IL287261A (en) 2021-12-01

Family

ID=72751365

Family Applications (1)

Application Number Title Priority Date Filing Date
IL287261A IL287261A (en) 2019-04-10 2021-10-07 Compounds and methods for detecting analytes using bioluminescence

Country Status (11)

Country Link
US (2) US20200386748A1 (enExample)
EP (1) EP3953374A4 (enExample)
JP (2) JP7645812B2 (enExample)
KR (1) KR20220007058A (enExample)
CN (1) CN113891895A (enExample)
AU (1) AU2020272037B2 (enExample)
BR (1) BR112021020354A2 (enExample)
CA (1) CA3135195A1 (enExample)
IL (1) IL287261A (enExample)
SG (1) SG11202110773RA (enExample)
WO (1) WO2020210658A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
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AU2020392245A1 (en) 2019-11-27 2022-06-23 Promega Corporation Multipartite luciferase peptides and polypeptides
US20220396830A1 (en) * 2021-05-13 2022-12-15 Promega Corporation Bioluminescent detection of dna synthesis
WO2023028175A1 (en) * 2021-08-24 2023-03-02 Kaya17 Inc. System and method for detecting presence of a target bioparticle in a sample via a vertical flow assay
CN113786873B (zh) * 2021-08-31 2022-09-23 广西横县张一元饮品有限公司 一种用于食品安全检测的试管
JPWO2023053586A1 (enExample) * 2021-09-29 2023-04-06
CN114231401B (zh) * 2022-02-21 2022-05-03 北京芯迈微生物技术有限公司 一种核酸检测试剂盒及检测方法
WO2023200703A1 (en) * 2022-04-15 2023-10-19 Siemens Healthcare Diagnostics Inc. Creatinine lateral flow assay devices and methods of production and use thereof
GB2619059A (en) * 2022-05-26 2023-11-29 Univ Leeds Innovations Ltd Split reporter complex
WO2024129040A1 (en) * 2022-12-16 2024-06-20 T.C Ankara Universitesi Rektorlugu A card test for the hallucinogenic psilocybin molecule that allows the diagnosis of toxic mushrooms and mushroom toxicities
CN116218907B (zh) * 2023-02-20 2025-04-22 复旦大学附属中山医院 带有HiBiT新型报告基因的肠道病毒感染性克隆及其构建方法和应用
WO2024216135A1 (en) * 2023-04-12 2024-10-17 Promega Corporation Poloxamer-stabilized reagents
WO2025024530A1 (en) * 2023-07-25 2025-01-30 The General Hospital Corporation Aldehyde binding optical imaging probes methods of use thereof
CN118033130B (zh) * 2024-01-19 2024-07-30 武汉科技大学 同时检测艾滋病、梅毒和丙肝的表面、微孔板、组件、方法及应用
CN118255903B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种检测非洲猪瘟病毒抗体的融合抗原、制备方法及检测试剂盒
CN118344492B (zh) * 2024-05-07 2025-03-11 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种纳米荧光素酶融合抗原在非洲猪瘟病毒抗体检测中的应用

Family Cites Families (15)

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US3423290A (en) * 1966-08-03 1969-01-21 Nasa Lyophilized reaction mixtures
US6045254A (en) * 1996-12-26 2000-04-04 M.L.I.S. Projects Ltd. Container having two or more compartments
US7118878B1 (en) * 2000-06-09 2006-10-10 Promega Corporation Method for increasing luminescence assay sensitivity
EP2325328B1 (en) * 2002-12-23 2014-02-12 Promega Corporation Improved luciferase-based assays
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
CA2659773A1 (en) * 2006-02-21 2007-08-30 Nanogen, Inc. Methods and compositions for analyte detection
US10067149B2 (en) * 2012-12-12 2018-09-04 Promega Corporation Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer
CA3174484A1 (en) 2012-12-12 2014-06-19 Promega Corporation Recognition of cellular target binding by a bioactive agent using intracellular bioluminescence resonance energy transfer
BR112015023394B8 (pt) * 2013-03-15 2023-09-26 Promega Corp Sistema e complexo bioluminescente
JP6814132B2 (ja) * 2014-09-12 2021-01-13 プロメガ コーポレイションPromega Corporation 内部タンパク質タグ
EP4455668A3 (en) * 2015-02-05 2025-02-19 Promega Corporation Luciferase-based thermal shift assays
US20170328896A1 (en) * 2016-02-19 2017-11-16 Insight Instruments, Inc. Assay systems for point of care detection of ocular analytes
US10634680B2 (en) * 2016-04-26 2020-04-28 University Of Utah Research Foundation Target-binding activated split reporter systems for analyte detection and related components and methods
US11327072B2 (en) 2017-02-09 2022-05-10 Promega Corporation Analyte detection immunoassay
JP6990369B2 (ja) * 2017-05-19 2022-02-03 国立大学法人 熊本大学 遺伝性腎疾患アルポート症候群治療薬に係る評価系

Also Published As

Publication number Publication date
JP2025133108A (ja) 2025-09-10
KR20220007058A (ko) 2022-01-18
CN113891895A (zh) 2022-01-04
SG11202110773RA (en) 2021-10-28
JP7645812B2 (ja) 2025-03-14
US20200386748A1 (en) 2020-12-10
AU2020272037A1 (en) 2021-12-02
EP3953374A4 (en) 2023-06-07
AU2020272037B2 (en) 2025-11-27
CA3135195A1 (en) 2020-10-15
EP3953374A1 (en) 2022-02-16
BR112021020354A2 (pt) 2021-12-14
US20250264464A1 (en) 2025-08-21
JP2022526013A (ja) 2022-05-20
WO2020210658A1 (en) 2020-10-15

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