JP7619958B2 - 組換えアデノ随伴ウイルス及びその使用 - Google Patents

組換えアデノ随伴ウイルス及びその使用 Download PDF

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JP7619958B2
JP7619958B2 JP2021559079A JP2021559079A JP7619958B2 JP 7619958 B2 JP7619958 B2 JP 7619958B2 JP 2021559079 A JP2021559079 A JP 2021559079A JP 2021559079 A JP2021559079 A JP 2021559079A JP 7619958 B2 JP7619958 B2 JP 7619958B2
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seq
amino acid
raav
capsid protein
capsid
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JP2022528416A5 (https=
JPWO2020206189A5 (https=
JP2022528416A (ja
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ダノス,オリビエ
リウ,イェ
マーサー,アンドリュー
ヨースト,サマンサ
メレチル,サブハ カルムチル
フィルンバーグ,エラド
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リジェネックスバイオ インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141Use of virus, viral particle or viral elements as a vector
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    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14111Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151Methods of production or purification of viral material
    • C12N2750/14152Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2021559079A 2019-04-04 2020-04-02 組換えアデノ随伴ウイルス及びその使用 Active JP7619958B2 (ja)

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JP2025003555A JP2025069170A (ja) 2019-04-04 2025-01-09 組換えアデノ随伴ウイルス及びその使用

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US201962829608P 2019-04-04 2019-04-04
US62/829,608 2019-04-04
US201962833516P 2019-04-12 2019-04-12
US62/833,516 2019-04-12
US201962839368P 2019-04-26 2019-04-26
US62/839,368 2019-04-26
US201962924107P 2019-10-21 2019-10-21
US62/924,107 2019-10-21
US202062963512P 2020-01-20 2020-01-20
US62/963,512 2020-01-20
PCT/US2020/026485 WO2020206189A1 (en) 2019-04-04 2020-04-02 Recombinant adeno-associated viruses and uses thereof

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US (1) US20220186256A1 (https=)
EP (1) EP3947420A1 (https=)
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CN (1) CN114127089A (https=)
CA (1) CA3135798A1 (https=)
IL (1) IL286911A (https=)
MX (1) MX2021011963A (https=)
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