JP7576905B2 - バレリアン組成物及び関連方法 - Google Patents

バレリアン組成物及び関連方法 Download PDF

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Publication number
JP7576905B2
JP7576905B2 JP2018558279A JP2018558279A JP7576905B2 JP 7576905 B2 JP7576905 B2 JP 7576905B2 JP 2018558279 A JP2018558279 A JP 2018558279A JP 2018558279 A JP2018558279 A JP 2018558279A JP 7576905 B2 JP7576905 B2 JP 7576905B2
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dosage form
pharmaceutical dosage
root extract
release portion
valerian
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Japanese (ja)
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JP2019514977A (ja
JP2019514977A5 (enExample
Inventor
エム． シャー，サイド
ディオリオ，クリストファー
ハッサン，ダニエル
ハッサン，フレッド
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ソシエテ・デ・プロデュイ・ネスレ・エス・アー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/76—Salicaceae (Willow family), e.g. poplar
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/84—Valerianaceae (Valerian family), e.g. valerian
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2018558279A 2016-05-06 2017-05-04 バレリアン組成物及び関連方法 Active JP7576905B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022089010A JP7577090B2 (ja) 2016-05-06 2022-05-31 バレリアン組成物及び関連方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662332728P 2016-05-06 2016-05-06
US62/332,728 2016-05-06
PCT/US2017/031046 WO2017192843A1 (en) 2016-05-06 2017-05-04 Valerian composition and related methods

Related Child Applications (1)

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Publication Number Publication Date
JP2019514977A JP2019514977A (ja) 2019-06-06
JP2019514977A5 JP2019514977A5 (enExample) 2022-01-06
JP7576905B2 true JP7576905B2 (ja) 2024-11-01

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JP2022089010A Active JP7577090B2 (ja) 2016-05-06 2022-05-31 バレリアン組成物及び関連方法

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Country Status (10)

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US (4) US10342873B2 (enExample)
EP (1) EP3452020A4 (enExample)
JP (2) JP7576905B2 (enExample)
KR (1) KR20190008265A (enExample)
CN (2) CN109310638A (enExample)
AU (1) AU2017260019A1 (enExample)
CA (1) CA3023305C (enExample)
MX (1) MX2018013569A (enExample)
RU (1) RU2018142019A (enExample)
WO (1) WO2017192843A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11723862B2 (en) * 2020-01-17 2023-08-15 Societe Des Produits Nestle S.A. Dosage form with sustained release melatonin pellets
IT202200013576A1 (it) * 2022-06-27 2023-12-27 S I I T S R L Servizio Int Imballaggi Termosaldanti Compressa multistrato a rilascio differenziato di melatonina e principi attivi

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2699075A1 (fr) 1992-12-11 1994-06-17 Rech Sarl Ab Préparation médicinale à libération programmable dans le temps notamment à base de plantes.
JP2003505426A (ja) 1999-07-21 2003-02-12 アンシル ファーマシューティカルズ，インコーポレイテッド バレリアン根の抽出方法
JP2005516944A (ja) 2001-12-20 2005-06-09 アルペックス ファーマ ソシエテ アノニム 微粒子組成物
JP2008515870A (ja) 2004-10-11 2008-05-15 ナサリーズ・ピーピーエム・リミテッド 経鼻投与用組成物
US20090197974A1 (en) 2008-02-05 2009-08-06 Khaleeq Ahmed Natural dietary supplement tablet
CN102247443A (zh) 2010-12-23 2011-11-23 祝凤仪 治疗神经衰弱中药外洗粉、泡腾片的配方及其制备方法
US20120195968A1 (en) 2011-01-28 2012-08-02 Shah Syed M Controlled-release melatonin compositions and related methods

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2713636B1 (fr) 1993-12-07 1996-01-05 Adir Nouveaux dérivés naphtaléniques, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent.
FR2727315A1 (fr) 1994-11-30 1996-05-31 Cooperative Agricole Laitiere Utilisation d'un decapeptide a activite de type benzodiazepine pour la preparation de medicaments et de complements alimentaires
US5840332A (en) 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
US6034239A (en) 1996-03-08 2000-03-07 Takeda Chemical Industries, Ltd. Tricyclic compounds, their production and use
WO1998025606A1 (en) 1996-12-10 1998-06-18 Bristol-Myers Squibb Company Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agents
US6419956B1 (en) * 1999-12-30 2002-07-16 Ancile Pharmaceuticals Odor-masking coating for a pharmaceutical preparation
US20050129783A1 (en) 2001-04-19 2005-06-16 Mccleary Edward L. Composition and method for treatment of neurophysiological conditions and maintenance of neurophysiological health
WO2005097101A1 (ja) * 2004-04-06 2005-10-20 Taiyokagaku Co., Ltd. 睡眠改善用組成物
JP5154924B2 (ja) 2004-05-11 2013-02-27 エガレット エイ／エス ジェランガムを含む膨張可能な投与形態
AU2006260201B2 (en) 2005-06-22 2011-10-20 Takeda Pharmaceutical Company Limited Tablet containing hardly soluble active ingredient
CA2642761A1 (en) * 2006-02-23 2007-08-30 Iomedix Sleep International Srl Compositions and methods for the induction and maintenance of quality sleep
CN1850212A (zh) * 2006-02-28 2006-10-25 潮州市强基制药厂 一种缬草油液体硬胶囊及其制备方法
WO2008037707A2 (de) 2006-09-27 2008-04-03 Finzelberg Gmbh & Co. Kg Baldrian-extraktzubereitung
US20080248106A1 (en) 2007-04-05 2008-10-09 Marvin Heuer Melatonin-based composition for improved sleep
WO2010084182A1 (en) 2009-01-23 2010-07-29 Universität Wien Methods for making valerenic acid derivatives and their use
US20110064720A1 (en) 2009-09-16 2011-03-17 Daniel Moses Amato Dietary Supplement Compositions and Methods of Making and Using the Same
CN102370833B (zh) * 2010-08-17 2014-03-26 北京亚东生物制药有限公司 一种解表祛暑的泡腾剂及其制备方法和用途
CN102058630B (zh) * 2010-12-16 2014-03-19 苏州大学 一种镇静安神的缬草制剂及其制备方法
CN103429223A (zh) 2011-01-17 2013-12-04 武田药品工业株式会社 口腔分散片
CN102114060B (zh) * 2011-02-22 2012-12-12 都晓伟 黑水缬草提取物及其制备方法和应用
JP2013053144A (ja) * 2011-08-09 2013-03-21 Daiichi Sankyo Healthcare Co Ltd 鎮静剤組成物
US20130116215A1 (en) * 2011-10-28 2013-05-09 Mireia Coma Combination therapies for treating neurological disorders
EP2806756B1 (en) 2012-01-26 2021-10-27 Incredible Foods, Inc. Enclosing materials in natural transport systems
EP4502609A3 (en) 2012-01-26 2025-04-09 Vanda Pharmaceuticals Inc. Determining a circadian rhythm
WO2014083438A2 (en) 2012-11-09 2014-06-05 Abattis Bioceuticals Corp Nitric oxide increasing nutritional supplements and methods
US20140271890A1 (en) 2013-03-14 2014-09-18 Thaer Ahmad Controlled-release pharmaceutical composition
HUE042996T2 (hu) 2013-04-23 2019-07-29 Zx Pharma Llc Bélben oldódó bevonatú, fehérjetartalmú alapbevonattal ellátott, több részecskét tartalmazó készítmény
PL231923B1 (pl) 2013-10-28 2019-04-30 Proteon Pharmaceuticals Spolka Akcyjna Sposób enkapsulacji materiału zawierającego bakteriofagi, otrzymywana nim mikrokapsułka oraz jej zastosowania
RU2535020C1 (ru) 2014-01-23 2014-12-10 Карпов Алексей Николаевич Фармацевтическая композиция седативного и спазмолитического действия
EP3632416A1 (en) * 2014-02-06 2020-04-08 Lan Bo Chen Composition and method for aiding sleep
CA2948070C (en) * 2014-05-05 2024-02-13 Boehringer Ingelheim International Gmbh Fast dissolving granulate
HUE031669T2 (en) 2014-07-14 2017-07-28 Dr Willmar Schwabe Gmbh & Co Kg Cataract extract and lavender oil combination for sleeping disorders

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2699075A1 (fr) 1992-12-11 1994-06-17 Rech Sarl Ab Préparation médicinale à libération programmable dans le temps notamment à base de plantes.
JP2003505426A (ja) 1999-07-21 2003-02-12 アンシル ファーマシューティカルズ，インコーポレイテッド バレリアン根の抽出方法
JP2005516944A (ja) 2001-12-20 2005-06-09 アルペックス ファーマ ソシエテ アノニム 微粒子組成物
JP2008515870A (ja) 2004-10-11 2008-05-15 ナサリーズ・ピーピーエム・リミテッド 経鼻投与用組成物
US20090197974A1 (en) 2008-02-05 2009-08-06 Khaleeq Ahmed Natural dietary supplement tablet
CN102247443A (zh) 2010-12-23 2011-11-23 祝凤仪 治疗神经衰弱中药外洗粉、泡腾片的配方及其制备方法
US20120195968A1 (en) 2011-01-28 2012-08-02 Shah Syed M Controlled-release melatonin compositions and related methods

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