JP7546927B2 - 脂質結合体化コア足場を使用する高密度リポタンパク質模倣ナノ粒子 - Google Patents

脂質結合体化コア足場を使用する高密度リポタンパク質模倣ナノ粒子 Download PDF

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JP7546927B2
JP7546927B2 JP2021542150A JP2021542150A JP7546927B2 JP 7546927 B2 JP7546927 B2 JP 7546927B2 JP 2021542150 A JP2021542150 A JP 2021542150A JP 2021542150 A JP2021542150 A JP 2021542150A JP 7546927 B2 JP7546927 B2 JP 7546927B2
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hdl
spherical
dna
core
small molecule
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スティーブン イー. ヘンリック,
シー. シャド タックストン,
ソンビン ティー. グエン,
ボン ジン ホン,
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ノースウェスタン ユニバーシティ
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    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
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    • A61K31/655Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
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    • A61K31/713Double-stranded nucleic acids or oligonucleotides
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JP2021542150A 2019-01-24 2020-01-24 脂質結合体化コア足場を使用する高密度リポタンパク質模倣ナノ粒子 Active JP7546927B2 (ja)

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US201962796534P 2019-01-24 2019-01-24
US62/796,534 2019-01-24
PCT/US2020/015109 WO2020154705A1 (en) 2019-01-24 2020-01-24 High-density lipoprotein mimetic nanoparticles using lipid conjugated core scaffolds

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JP2022518479A JP2022518479A (ja) 2022-03-15
JP2022518479A5 JP2022518479A5 (https=) 2024-05-08
JP7546927B2 true JP7546927B2 (ja) 2024-09-09

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US (1) US12502354B2 (https=)
EP (1) EP3914236A4 (https=)
JP (1) JP7546927B2 (https=)
CN (1) CN113613635A (https=)
AU (2) AU2020210881A1 (https=)
CA (1) CA3127256A1 (https=)
MX (1) MX2021008940A (https=)
SG (1) SG11202107156WA (https=)
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