JP2022518479A5 - - Google Patents
Info
- Publication number
- JP2022518479A5 JP2022518479A5 JP2021542150A JP2021542150A JP2022518479A5 JP 2022518479 A5 JP2022518479 A5 JP 2022518479A5 JP 2021542150 A JP2021542150 A JP 2021542150A JP 2021542150 A JP2021542150 A JP 2021542150A JP 2022518479 A5 JP2022518479 A5 JP 2022518479A5
- Authority
- JP
- Japan
- Prior art keywords
- hdl
- spherical
- core
- dna
- spherical hdl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962796534P | 2019-01-24 | 2019-01-24 | |
| US62/796,534 | 2019-01-24 | ||
| PCT/US2020/015109 WO2020154705A1 (en) | 2019-01-24 | 2020-01-24 | High-density lipoprotein mimetic nanoparticles using lipid conjugated core scaffolds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022518479A JP2022518479A (ja) | 2022-03-15 |
| JP2022518479A5 true JP2022518479A5 (https=) | 2024-05-08 |
| JP7546927B2 JP7546927B2 (ja) | 2024-09-09 |
Family
ID=71736549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021542150A Active JP7546927B2 (ja) | 2019-01-24 | 2020-01-24 | 脂質結合体化コア足場を使用する高密度リポタンパク質模倣ナノ粒子 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12502354B2 (https=) |
| EP (1) | EP3914236A4 (https=) |
| JP (1) | JP7546927B2 (https=) |
| CN (1) | CN113613635A (https=) |
| AU (2) | AU2020210881A1 (https=) |
| CA (1) | CA3127256A1 (https=) |
| MX (1) | MX2021008940A (https=) |
| SG (1) | SG11202107156WA (https=) |
| WO (1) | WO2020154705A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011207563B2 (en) | 2010-01-19 | 2016-03-10 | Northwestern University | Synthetic nanostructures including nucleic acids and/or other entities |
| HRP20240586T1 (hr) | 2018-10-09 | 2024-07-19 | The University Of British Columbia | Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima |
| US20230173096A1 (en) * | 2020-05-18 | 2023-06-08 | Northwestern University | Targeted antiviral drugs |
| CA3199462A1 (en) | 2020-10-23 | 2022-04-28 | Northwestern University | Hydrophobic drugs in organic core high density lipoprotein (hdl) nanoparticles |
| KR102402620B1 (ko) * | 2021-06-01 | 2022-05-30 | 임덕수 | 약물 전달을 위한 고밀도 지단백 모방 고형 지질 나노입자 및 이의 용도 |
| WO2025043049A2 (en) * | 2023-08-22 | 2025-02-27 | Northwestern University | Lipoprotein-like nanoparticles with an organic core and use thereof |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2677272B1 (fr) * | 1991-06-05 | 1995-03-03 | Biovecteurs As | Vecteur particulaire a tropisme selectif, procede de preparation et composition pharmaceutique. |
| US6506564B1 (en) | 1996-07-29 | 2003-01-14 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US6361944B1 (en) | 1996-07-29 | 2002-03-26 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| WO2006138145A1 (en) | 2005-06-14 | 2006-12-28 | Northwestern University | Nucleic acid functionalized nanoparticles for therapeutic applications |
| EP2121987B1 (en) | 2007-02-09 | 2012-06-13 | Northwestern University | Particles for detecting intracellular targets |
| CA2679586A1 (en) | 2007-02-27 | 2008-10-23 | Northwestern University | Molecule attachment to nanoparticles |
| EP2160464B1 (en) | 2007-05-30 | 2014-05-21 | Northwestern University | Nucleic acid functionalized nanoparticles for therapeutic applications |
| EP2288336B8 (en) | 2008-04-25 | 2017-03-22 | Northwestern University | Nanostructures suitable for sequestering cholesterol |
| WO2011017456A2 (en) | 2009-08-04 | 2011-02-10 | Northwestern University | Localized delivery of nanoparticles for therapeutic and diagnostic applications |
| US20120244230A1 (en) | 2009-09-01 | 2012-09-27 | Massachusetts Institute Of Technology | Polyvalent polynucleotide nanoparticle conjugates as delivery vehicles for a chemotherapeutic agent |
| US20110111974A1 (en) | 2009-10-23 | 2011-05-12 | Northwestern University | Short Duplex Probes for Enhanced Target Hybridization |
| CA2779099C (en) | 2009-10-30 | 2021-08-10 | Northwestern University | Templated nanoconjugates |
| WO2011079290A1 (en) | 2009-12-24 | 2011-06-30 | Northwestern University | Oligonucleotide specific uptake of nanoconjugates |
| AU2011207563B2 (en) | 2010-01-19 | 2016-03-10 | Northwestern University | Synthetic nanostructures including nucleic acids and/or other entities |
| US20140134658A1 (en) | 2010-05-21 | 2014-05-15 | Notrhwestern University, An Illinois Not For Profit Corporation | Psa enzymatic activity: a new biomarker for assessing prostate cancer aggressiveness |
| WO2013033513A1 (en) * | 2011-08-31 | 2013-03-07 | University Of Georgia Research Foundation, Inc. | Apoptosis-targeting nanoparticles |
| AU2013222238A1 (en) | 2012-02-22 | 2014-09-18 | Northwestern University | Nanostructures for treating cancers and other conditions |
| US10568898B2 (en) | 2013-08-13 | 2020-02-25 | Northwestern University | Lipophilic nanoparticles for drug delivery |
| WO2015168393A1 (en) | 2014-04-30 | 2015-11-05 | Northwestern University | Nanostructures for modulating intercellular communication and uses thereof |
| US10413565B2 (en) | 2014-04-30 | 2019-09-17 | Northwestern University | Nanostructures for modulating intercellular communication and uses thereof |
| DE102014112088A1 (de) * | 2014-08-25 | 2016-02-25 | Karlsruher Institut für Technologie | Verfahren zur Herstellung mikroporöser organischer Membranen, mikroporöse organische Membranen und deren Verwendung |
| US10517924B2 (en) | 2014-11-24 | 2019-12-31 | Northwestern University | High density lipoprotein nanoparticles for inflammation |
| EP3236955A1 (en) * | 2014-12-22 | 2017-11-01 | University of Georgia Research Foundation Inc. | Nanoparticles for lipid homeostasis |
| US10078092B2 (en) | 2015-03-18 | 2018-09-18 | Northwestern University | Assays for measuring binding kinetics and binding capacity of acceptors for lipophilic or amphiphilic molecules |
| EP4414028A3 (en) | 2015-05-19 | 2024-11-27 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
| CA3008837A1 (en) | 2015-12-18 | 2017-06-22 | Northwestern University | Nitric oxide releasing high density lipoprotein-like nanoparticles (no hdl nps) |
| SG11201807589RA (en) | 2016-03-08 | 2018-10-30 | Univ Northwestern | Delivery of nitric oxide-releasing phospholipids, liposomes, and high density lipoprotein-like nanoparticles (hdl nps) by drug eluting stents and intra-arterial injection |
| US10967072B2 (en) | 2016-04-27 | 2021-04-06 | Northwestern University | Short interfering RNA templated lipoprotein particles (siRNA-TLP) |
| MX2019002996A (es) | 2016-09-15 | 2019-09-18 | Univ Northwestern | Nanopartículas como sustratos catalíticos para biodetección en tiempo real del desempeño humano y diagnóstico y métodos terapéuticos. |
| US20210332404A1 (en) | 2017-06-21 | 2021-10-28 | Northwestern University | Lipid nanoparticles for measuring chronic and acute response to exercise |
| WO2020219833A1 (en) | 2019-04-26 | 2020-10-29 | Northwestern University | High density lipoprotein nanoparticles and rna templated lipoprotein particles for ocular therapy |
| EP3965746A4 (en) | 2019-05-10 | 2023-07-19 | Northwestern University | ORALLY ADMINISTERED LIPID NANOPARTICLES THAT TARGETING AND REVEALING INTESTINAL CD36 AS A MASTER REGULATOR OF SYSTEMIC LIPID HOMEOSTASIS WITH SEX-DIFFERENTIAL RESPONSES |
| AU2020350707A1 (en) | 2019-09-18 | 2022-03-31 | Northwestern University | High density lipoprotein-like nanoparticles as inducers of ferroptosis in cancer |
| US20230173096A1 (en) | 2020-05-18 | 2023-06-08 | Northwestern University | Targeted antiviral drugs |
| US12599677B2 (en) | 2020-10-05 | 2026-04-14 | Northwestern University | Targeted PH sensitive liposomes |
| CA3199462A1 (en) | 2020-10-23 | 2022-04-28 | Northwestern University | Hydrophobic drugs in organic core high density lipoprotein (hdl) nanoparticles |
-
2020
- 2020-01-24 US US17/425,401 patent/US12502354B2/en active Active
- 2020-01-24 AU AU2020210881A patent/AU2020210881A1/en not_active Abandoned
- 2020-01-24 EP EP20745880.3A patent/EP3914236A4/en active Pending
- 2020-01-24 CA CA3127256A patent/CA3127256A1/en active Pending
- 2020-01-24 MX MX2021008940A patent/MX2021008940A/es unknown
- 2020-01-24 JP JP2021542150A patent/JP7546927B2/ja active Active
- 2020-01-24 SG SG11202107156WA patent/SG11202107156WA/en unknown
- 2020-01-24 CN CN202080010616.0A patent/CN113613635A/zh active Pending
- 2020-01-24 WO PCT/US2020/015109 patent/WO2020154705A1/en not_active Ceased
-
2025
- 2025-11-03 AU AU2025260005A patent/AU2025260005A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022518479A5 (https=) | ||
| Hu et al. | Physiological barriers and strategies of lipid‐based nanoparticles for nucleic acid drug delivery | |
| US20260048010A1 (en) | Synthetic Nanostructures Including Nucleic Acids and/or Other Entities | |
| Allain et al. | Self-assembled nucleolipids: from supramolecular structure to soft nucleic acid and drug delivery devices | |
| CN101903018B (zh) | 用于递送核酸基因的ldl样阳离子纳米微粒、其制备方法以及使用其递送核酸基因的方法 | |
| JP4291412B2 (ja) | リポソーマルホスホジエステル、ホスホロチオエート、およびｐ−エトキシオリゴヌクレオチド | |
| US20100166842A1 (en) | Amphiphilic substances and functionalized lipid vesicles including the same | |
| JP2011503070A (ja) | 全身遺伝子送達のための自己構築型ミセル様ナノ粒子 | |
| US20080242625A1 (en) | Nucleotide-Cochleate Compositions And Methods Of Use | |
| CN101932310B (zh) | 制备基于官能两亲分子或者大分子的纳米颗粒的方法和其用途 | |
| WO2012124688A1 (ja) | 肺送達のためのベクター、導入剤及び使用 | |
| Zhang et al. | Construction of a targeting nanoparticle of 3′, 3 ″-bis-peptide-siRNA conjugate/mixed lipid with postinserted DSPE-PEG2000-cRGD | |
| Zhou et al. | Overcoming the delivery barrier of oligonucleotide drugs and enhancing nucleoside drug efficiency: The use of nucleolipids | |
| Le Gall et al. | Effects of a novel archaeal tetraether-based colipid on the in vivo gene transfer activity of two cationic amphiphiles | |
| Rouquette et al. | Adenosine and lipids: A forced marriage or a love match? | |
| CN107951861A (zh) | 一种脂质纳米粒膜材料组合物 | |
| CN101541307A (zh) | 自发形成的椭圆体磷脂单层囊泡 | |
| JP3910646B2 (ja) | 「細胞への遺伝子導入用組成物」 | |
| CN120787165A (zh) | 用于递送核酸载物的纳米颗粒 | |
| Pili et al. | Liposomal squalenoyl-gemcitabine: formulation, characterization and anticancer activity evaluation | |
| US20120178793A1 (en) | Nucleotide-cochleate compositions and methods of use | |
| EP1007097B1 (fr) | Formulation de particules agent(s) de transfection cationique(s)/acides nucleiques stabilisees | |
| EP3662934A1 (en) | Composition for gene therapy of the central nervous system, process of production and use thereof | |
| Sharma et al. | Liposomes: vesicular system an overview | |
| Aranda-Lara et al. | Small Interfering RNA Carriers for Oncotherapy: A Preclinical Overview |