JP7531916B2 - 食道癌バイオマーカー及びその用途 - Google Patents

食道癌バイオマーカー及びその用途 Download PDF

Info

Publication number
JP7531916B2
JP7531916B2 JP2021536655A JP2021536655A JP7531916B2 JP 7531916 B2 JP7531916 B2 JP 7531916B2 JP 2021536655 A JP2021536655 A JP 2021536655A JP 2021536655 A JP2021536655 A JP 2021536655A JP 7531916 B2 JP7531916 B2 JP 7531916B2
Authority
JP
Japan
Prior art keywords
esophageal cancer
mir
hsa
urinary
biomarker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2021536655A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2021019944A1 (https=
JPWO2021019944A5 (https=
Inventor
貴也 志村
悠介 奥田
弘靖 岩崎
洋望 片岡
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagoya City University
Original Assignee
Nagoya City University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagoya City University filed Critical Nagoya City University
Publication of JPWO2021019944A1 publication Critical patent/JPWO2021019944A1/ja
Publication of JPWO2021019944A5 publication Critical patent/JPWO2021019944A5/ja
Application granted granted Critical
Publication of JP7531916B2 publication Critical patent/JP7531916B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021536655A 2019-07-29 2020-06-18 食道癌バイオマーカー及びその用途 Active JP7531916B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019139247 2019-07-29
JP2019139247 2019-07-29
PCT/JP2020/024027 WO2021019944A1 (ja) 2019-07-29 2020-06-18 食道癌バイオマーカー及びその用途

Publications (3)

Publication Number Publication Date
JPWO2021019944A1 JPWO2021019944A1 (https=) 2021-02-04
JPWO2021019944A5 JPWO2021019944A5 (https=) 2022-06-20
JP7531916B2 true JP7531916B2 (ja) 2024-08-13

Family

ID=74230244

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021536655A Active JP7531916B2 (ja) 2019-07-29 2020-06-18 食道癌バイオマーカー及びその用途

Country Status (4)

Country Link
US (1) US20220325354A1 (https=)
EP (1) EP4006151A4 (https=)
JP (1) JP7531916B2 (https=)
WO (1) WO2021019944A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112877434A (zh) * 2021-02-22 2021-06-01 南充市中心医院 一组用于检测食管癌组织的circRNA标志物、引物及其应用和含有其的试剂盒
CN112813169A (zh) * 2021-02-26 2021-05-18 南充市中心医院 一种用于检测食管癌组织的jam-a生物标志物、引物及其应用和含有其的试剂盒
CN114854855A (zh) * 2022-02-22 2022-08-05 武汉艾米森生命科技有限公司 食管癌的生物标志物、核酸产品和试剂盒

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015194615A1 (ja) 2014-06-18 2015-12-23 東レ株式会社 肝臓がんの検出キット又はデバイス及び検出方法
WO2015194627A1 (ja) 2014-06-18 2015-12-23 東レ株式会社 食道がんの検出キット又はデバイス及び検出方法
JP2016144439A (ja) 2015-01-30 2016-08-12 ロート製薬株式会社 細胞の品質を評価する方法、及び細胞の品質判定キット
JP2018074938A (ja) 2016-11-08 2018-05-17 東レ株式会社 悪性骨軟部腫瘍の検出用キット又はデバイス及び検出方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE362532T1 (de) 1999-03-19 2007-06-15 Takara Bio Inc Verfahren zur amplifizierung einer nukleinsäuresequenz unter verwendung eines chimären primers
JP3883476B2 (ja) 1999-03-19 2007-02-21 タカラバイオ株式会社 核酸配列の増幅方法
US10077316B2 (en) 2013-12-27 2018-09-18 National University Corporation, Kochi University Esophageal cancer marker and use thereof
DE102015208087A1 (de) 2015-04-30 2016-11-03 Carl Zeiss Microscopy Gmbh Verfahren zum Generieren eines reflektionsreduzierten Kontrastbildes und diesbezügliche Vorrichtungen
CN106834470A (zh) * 2017-02-17 2017-06-13 张灏 miRNA在制备癌症诊断试剂盒中的用途

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015194615A1 (ja) 2014-06-18 2015-12-23 東レ株式会社 肝臓がんの検出キット又はデバイス及び検出方法
WO2015194627A1 (ja) 2014-06-18 2015-12-23 東レ株式会社 食道がんの検出キット又はデバイス及び検出方法
JP2016144439A (ja) 2015-01-30 2016-08-12 ロート製薬株式会社 細胞の品質を評価する方法、及び細胞の品質判定キット
JP2018074938A (ja) 2016-11-08 2018-05-17 東レ株式会社 悪性骨軟部腫瘍の検出用キット又はデバイス及び検出方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MATSUI, D. et al，Unique miRNA Profiles for Disease Progression of Human Esophageal Adenocarcinoma，Gastroenterology，2016年，Vol.150, Issue 4, Supplement 1，S358

Also Published As

Publication number Publication date
EP4006151A4 (en) 2023-10-25
JPWO2021019944A1 (https=) 2021-02-04
US20220325354A1 (en) 2022-10-13
WO2021019944A1 (ja) 2021-02-04
EP4006151A1 (en) 2022-06-01

Similar Documents

Publication Publication Date Title
JP7676321B2 (ja) 胃がんを診断するためのｍｉＲＮＡマーカーの組み合わせ物、およびキット
KR102354660B1 (ko) 정량 pcr, 프라이머 및 키트에 의한 인간 대변 시료로부터의 대장암의 진단 방법
US20100255481A1 (en) Method for detection of adenoma or cancer by genetic analysis
JP7531916B2 (ja) 食道癌バイオマーカー及びその用途
CN102947468B (zh) 大肠肿瘤的检测方法
CN110484624B (zh) 一种基于外周血的胃癌生物标志物及其检测方法和应用
CN104975075B (zh) 一种用于IgA肾病检测的系统、方法及方法的建立
El Hadi et al. Development and evaluation of a novel RT-qPCR based test for the quantification of HER2 gene expression in breast cancer
JP7345860B2 (ja) 胃癌バイオマーカー及びその用途
JP6608424B2 (ja) 前癌性結腸直腸ポリープおよび結腸直腸癌を特定するための方法およびキット
TWI571514B (zh) 評估罹患大腸直腸癌風險的方法
JP7239973B2 (ja) 前癌病変又は癌の有無の予測を補助する方法
JP7299765B2 (ja) マイクロｒｎａ測定方法およびキット
JP7610265B2 (ja) 大腸癌診断用マーカー、大腸癌の診断を補助する方法、大腸癌の診断のためにデータを収集する方法、大腸癌の診断用キット、大腸癌治療薬、大腸癌の治療方法、大腸癌の診断方法
CN103911436A (zh) 一种非贲门胃癌早期诊断的血清/血浆miRNA标志物及其应用
US20150087549A1 (en) Methods of using tissue biomarkers for indication of progression from barretts esophagus to esophageal adenocarcinoma
JP5586164B2 (ja) 潰瘍性大腸炎患者の癌化リスクを決定する方法
CN111763736A (zh) 用于诊断甲状腺乳头状癌淋巴结转移的液体活检试剂盒
JP2025001351A (ja) 分析方法、キット及び検出用デバイス
RU2678227C1 (ru) Малоинвазивный способ диагностики рака легкого на основании изменения копийности локуса мтДНК HV2
WO2024204603A1 (ja) 膀胱癌のバイオマーカー
WO2026090778A1 (zh) 用于检测胃癌的标志物、试剂盒及其应用
EP4028559A1 (en) Methods for diagnosis and in vitro risk stratification for head and neck cancer based on exosomal mrnas

Legal Events

Date Code Title Description
A529 Written submission of copy of amendment under article 34 pct

Free format text: JAPANESE INTERMEDIATE CODE: A5211

Effective date: 20211221

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20230531

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240423

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240516

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240611

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240619

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20240709

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20240724

R150 Certificate of patent or registration of utility model

Ref document number: 7531916

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S631 Written request for registration of reclamation of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313631

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350