JP7518819B2 - 歯周病予防、改善又は治療剤 - Google Patents

歯周病予防、改善又は治療剤 Download PDF

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Publication number
JP7518819B2
JP7518819B2 JP2021519456A JP2021519456A JP7518819B2 JP 7518819 B2 JP7518819 B2 JP 7518819B2 JP 2021519456 A JP2021519456 A JP 2021519456A JP 2021519456 A JP2021519456 A JP 2021519456A JP 7518819 B2 JP7518819 B2 JP 7518819B2
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Prior art keywords
periodontal disease
expression
preventing
cells
s1pc
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Japanese (ja)
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JPWO2020230813A1 (https=
Inventor
政博 大谷
翼 西村
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Wakunaga Pharmaceutical Co Ltd
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Wakunaga Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021519456A 2019-05-14 2020-05-13 歯周病予防、改善又は治療剤 Active JP7518819B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019091444 2019-05-14
JP2019091444 2019-05-14
PCT/JP2020/019096 WO2020230813A1 (ja) 2019-05-14 2020-05-13 歯周病予防、改善又は治療剤

Publications (2)

Publication Number Publication Date
JPWO2020230813A1 JPWO2020230813A1 (https=) 2020-11-19
JP7518819B2 true JP7518819B2 (ja) 2024-07-18

Family

ID=73289457

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JP2021519456A Active JP7518819B2 (ja) 2019-05-14 2020-05-13 歯周病予防、改善又は治療剤

Country Status (4)

Country Link
US (1) US12403112B2 (https=)
EP (1) EP3970793A4 (https=)
JP (1) JP7518819B2 (https=)
WO (1) WO2020230813A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112521322B (zh) * 2020-12-14 2022-08-26 上海市第十人民医院 氨基酸类化合物及组合物及其用于治疗牙周疾病的用途
CA3216695A1 (en) 2021-04-13 2022-10-20 Wakunaga Pharmaceutical Co., Ltd. Sirtuin or klotho activator or expression enhancer, nad+ increasing agent, and senolytic agent
KR20250002480A (ko) 2022-04-13 2025-01-07 와쿠나가 세이야쿠 가부시키 가이샤 eNAMPT 증가제, 시르투인 활성화 또는 발현 증강제, NAD+ 증가제, 및 노화 세포 억제제

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004123630A (ja) 2002-10-03 2004-04-22 Chisso Corp 抗う蝕、抗歯周病性組成物
US20120189710A1 (en) 2009-07-28 2012-07-26 Steggles Raymond S Antibacterial compositions
WO2016088892A1 (ja) 2014-12-05 2016-06-09 湧永製薬株式会社 免疫機能調整剤
WO2016199885A1 (ja) 2015-06-12 2016-12-15 湧永製薬株式会社 血圧降下剤
WO2019031442A1 (ja) 2017-08-07 2019-02-14 湧永製薬株式会社 血流改善剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62423A (ja) 1985-06-25 1987-01-06 Wakunaga Pharmaceut Co Ltd 肝疾患治療剤
US20140050677A1 (en) * 2006-05-24 2014-02-20 David Michael Ott Personal care and medicinal products incorporating bound organosulfur groups
KR101188746B1 (ko) * 2009-09-23 2012-10-11 주식회사파마킹 에스-알릴-엘-시스테인을 유효성분으로 포함하는 위장질환 예방 또는 치료용 조성물
US20170071839A1 (en) * 2015-09-11 2017-03-16 David Michael Ott Personal care and medicinal products incorporating organosulfur groups
RU2019128445A (ru) * 2017-03-30 2021-04-30 Моотрал Са Противомикробные композиции, содержащие чеснок
CN109692143A (zh) * 2019-01-24 2019-04-30 孔来根 具有黑蒜提取物的牙膏

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004123630A (ja) 2002-10-03 2004-04-22 Chisso Corp 抗う蝕、抗歯周病性組成物
US20120189710A1 (en) 2009-07-28 2012-07-26 Steggles Raymond S Antibacterial compositions
WO2016088892A1 (ja) 2014-12-05 2016-06-09 湧永製薬株式会社 免疫機能調整剤
WO2016199885A1 (ja) 2015-06-12 2016-12-15 湧永製薬株式会社 血圧降下剤
WO2019031442A1 (ja) 2017-08-07 2019-02-14 湧永製薬株式会社 血流改善剤

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
許栄海，ニンニクの癌予防効果，医学のあゆみ，2003年，Vol.204, No.1，pp.74-79

Also Published As

Publication number Publication date
EP3970793A1 (en) 2022-03-23
JPWO2020230813A1 (https=) 2020-11-19
EP3970793A4 (en) 2023-01-18
WO2020230813A1 (ja) 2020-11-19
US20220273597A1 (en) 2022-09-01
US12403112B2 (en) 2025-09-02

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