JP7459063B2 - 抗－ｃｄ１９抗体薬物複合体に関連する組成物および方法 - Google Patents

抗－ｃｄ１９抗体薬物複合体に関連する組成物および方法 Download PDF

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JP7459063B2
JP7459063B2 JP2021513015A JP2021513015A JP7459063B2 JP 7459063 B2 JP7459063 B2 JP 7459063B2 JP 2021513015 A JP2021513015 A JP 2021513015A JP 2021513015 A JP2021513015 A JP 2021513015A JP 7459063 B2 JP7459063 B2 JP 7459063B2
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amino acid
seq
acid sequence
antibody
antibody conjugate
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JP2021523232A (ja
JP2021523232A5 (https=
Inventor
ヨン ソン，ホ
ヒ パク，ユン
ミン キム，スン
レ キム，ヒョン
ヘ オ，ジ
ミン リュ，ヒュン
チェ，ジェウク
ス オ，ヨン
ズ キム，ヨン
ディーハン，マウリーン
フィッシャー，ニコラス
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Ligachem Biosciences Inc
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Legochem Biosciences Inc
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2021513015A 2018-05-09 2019-05-09 抗－ｃｄ１９抗体薬物複合体に関連する組成物および方法 Active JP7459063B2 (ja)

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US201862669183P 2018-05-09 2018-05-09
US62/669,183 2018-05-09
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JP2024054141A (ja) * 2018-05-09 2024-04-16 レゴケム バイオサイエンシズ， インク． 抗－ｃｄ１９抗体薬物複合体に関連する組成物および方法

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