JP7404235B2 - 4-ピリミジンスルファミド誘導体のsglt-2阻害剤との、エンドセリン関連疾患治療用の合剤 - Google Patents

4-ピリミジンスルファミド誘導体のsglt-2阻害剤との、エンドセリン関連疾患治療用の合剤 Download PDF

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JP7404235B2
JP7404235B2 JP2020529550A JP2020529550A JP7404235B2 JP 7404235 B2 JP7404235 B2 JP 7404235B2 JP 2020529550 A JP2020529550 A JP 2020529550A JP 2020529550 A JP2020529550 A JP 2020529550A JP 7404235 B2 JP7404235 B2 JP 7404235B2
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aprocitentan
pharmaceutically acceptable
acceptable salt
sglt
treatment
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JP2021504423A (ja
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ベレ マルク
イグラルツ マルク
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Idorsia Pharmaceuticals Ltd
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    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61K9/2013Organic compounds, e.g. phospholipids, fats
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020529550A 2017-11-30 2018-11-29 4-ピリミジンスルファミド誘導体のsglt-2阻害剤との、エンドセリン関連疾患治療用の合剤 Active JP7404235B2 (ja)

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JP2023209979A JP7635355B2 (ja) 2017-11-30 2023-12-13 4-ピリミジンスルファミド誘導体のsglt-2阻害剤との、エンドセリン関連疾患治療用の合剤

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EP2017081050 2017-11-30
EPPCT/EP2017/081050 2017-11-30
PCT/EP2018/082947 WO2019106066A1 (en) 2017-11-30 2018-11-29 Combination of a 4-pyrimidinesulfamide derivative with an sglt-2 inhibitor for the treatment of endothelin related diseases

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JP2023209979A Active JP7635355B2 (ja) 2017-11-30 2023-12-13 4-ピリミジンスルファミド誘導体のsglt-2阻害剤との、エンドセリン関連疾患治療用の合剤

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WO2025089933A1 (ko) * 2023-10-24 2025-05-01 주식회사 레드엔비아 Sglt-2 저해제 및 dpp-4 저해제를 포함하는 혈관 또는 판막 협착증의 예방 또는 치료용 병용제제
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