JP7402167B2 - アルギナーゼ阻害剤 - Google Patents

アルギナーゼ阻害剤 Download PDF

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JP7402167B2
JP7402167B2 JP2020546139A JP2020546139A JP7402167B2 JP 7402167 B2 JP7402167 B2 JP 7402167B2 JP 2020546139 A JP2020546139 A JP 2020546139A JP 2020546139 A JP2020546139 A JP 2020546139A JP 7402167 B2 JP7402167 B2 JP 7402167B2
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cancer
group
pharmaceutical composition
arginase
acid
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JP2021516237A (ja
JP2021516237A5 (https=
JPWO2019173188A5 (https=
Inventor
ニコル フォーリー コリン
ルイーズ グレンジ レベッカ
ギュネイ テズキャン
カリシーク ヤロスワフ
トーマス ニューカム エリック
ツ トラン アン
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アーカス バイオサイエンシズ インコーポレイティド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2020546139A 2018-03-05 2019-03-04 アルギナーゼ阻害剤 Active JP7402167B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862638412P 2018-03-05 2018-03-05
US62/638,412 2018-03-05
PCT/US2019/020507 WO2019173188A1 (en) 2018-03-05 2019-03-04 Arginase inhibitors

Publications (4)

Publication Number Publication Date
JP2021516237A JP2021516237A (ja) 2021-07-01
JP2021516237A5 JP2021516237A5 (https=) 2022-03-14
JPWO2019173188A5 JPWO2019173188A5 (https=) 2022-03-14
JP7402167B2 true JP7402167B2 (ja) 2023-12-20

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JP2020546139A Active JP7402167B2 (ja) 2018-03-05 2019-03-04 アルギナーゼ阻害剤

Country Status (21)

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US (1) US12054500B2 (https=)
EP (1) EP3761992A4 (https=)
JP (1) JP7402167B2 (https=)
KR (1) KR102656571B1 (https=)
CN (1) CN111818928A (https=)
AU (1) AU2019229978B2 (https=)
BR (1) BR112020017604A2 (https=)
CA (1) CA3091805A1 (https=)
CL (1) CL2020002271A1 (https=)
CO (1) CO2020012060A2 (https=)
CR (1) CR20200445A (https=)
EA (1) EA202092086A1 (https=)
IL (1) IL276813B2 (https=)
MX (1) MX2020009290A (https=)
MY (1) MY205512A (https=)
PE (1) PE20210452A1 (https=)
PH (1) PH12020551352A1 (https=)
SG (1) SG11202008113RA (https=)
UA (1) UA127897C2 (https=)
WO (1) WO2019173188A1 (https=)
ZA (1) ZA202006006B (https=)

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US12240867B2 (en) 2018-12-18 2025-03-04 Merck Sharp & Dohme Llc Arginase inhibitors and methods of use
AU2021292195A1 (en) 2020-06-17 2023-01-05 Arcus Biosciences, Inc. Crystalline forms of a CD73 inhibitor and uses thereof
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WO2023077046A1 (en) 2021-10-29 2023-05-04 Arcus Biosciences, Inc. Inhibitors of hif-2alpha and methods of use thereof
CA3256561A1 (en) 2022-05-02 2023-11-09 Arcus Biosciences, Inc. Anti-tigit antibodies and their uses
EP4554680A1 (en) 2022-07-15 2025-05-21 Arcus Biosciences, Inc. Inhibitors of hpk1 and methods of use thereof
US20260028336A1 (en) 2022-07-20 2026-01-29 Arcus Biosciences, Inc. Cbl-b inhibitors and methods of use thereof
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WO2024081385A1 (en) 2022-10-14 2024-04-18 Arcus Biosciences, Inc. Hpk1 inhibitors and methods of use thereof
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EP4705292A1 (en) 2023-05-05 2026-03-11 Arcus Biosciences, Inc. Cbl-b inhibitors and methods of use thereof
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Also Published As

Publication number Publication date
PH12020551352A1 (en) 2021-06-21
ZA202006006B (en) 2025-02-26
PE20210452A1 (es) 2021-03-08
JP2021516237A (ja) 2021-07-01
CR20200445A (es) 2021-04-27
MY205512A (en) 2024-10-24
IL276813A (en) 2020-10-29
EP3761992A4 (en) 2021-11-24
CA3091805A1 (en) 2019-09-12
KR102656571B1 (ko) 2024-04-11
IL276813B1 (en) 2024-05-01
CO2020012060A2 (es) 2021-01-18
EP3761992A1 (en) 2021-01-13
AU2019229978A1 (en) 2020-10-15
US20210002306A1 (en) 2021-01-07
US12054500B2 (en) 2024-08-06
MX2020009290A (es) 2020-09-28
SG11202008113RA (en) 2020-09-29
BR112020017604A2 (pt) 2020-12-22
AU2019229978B2 (en) 2024-05-30
KR20200128117A (ko) 2020-11-11
CN111818928A (zh) 2020-10-23
IL276813B2 (en) 2024-09-01
EA202092086A1 (ru) 2021-02-09
CL2020002271A1 (es) 2021-04-09
WO2019173188A1 (en) 2019-09-12
UA127897C2 (uk) 2024-02-07

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