JP7369989B2 - 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物 - Google Patents

糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物 Download PDF

Info

Publication number
JP7369989B2
JP7369989B2 JP2019035709A JP2019035709A JP7369989B2 JP 7369989 B2 JP7369989 B2 JP 7369989B2 JP 2019035709 A JP2019035709 A JP 2019035709A JP 2019035709 A JP2019035709 A JP 2019035709A JP 7369989 B2 JP7369989 B2 JP 7369989B2
Authority
JP
Japan
Prior art keywords
group
formula
building block
integer
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019035709A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020138931A5 (enExample
JP2020138931A (ja
Inventor
敏材 野上
敏幸 伊藤
啓 酒井
智昭 濱多
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koganei Corp
Tottori University NUC
Original Assignee
Koganei Corp
Tottori University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koganei Corp, Tottori University NUC filed Critical Koganei Corp
Priority to JP2019035709A priority Critical patent/JP7369989B2/ja
Priority to US17/434,331 priority patent/US12404293B2/en
Priority to EP20763290.2A priority patent/EP3932930A4/en
Priority to PCT/JP2020/007365 priority patent/WO2020175440A1/ja
Publication of JP2020138931A publication Critical patent/JP2020138931A/ja
Publication of JP2020138931A5 publication Critical patent/JP2020138931A5/ja
Application granted granted Critical
Publication of JP7369989B2 publication Critical patent/JP7369989B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
JP2019035709A 2019-02-28 2019-02-28 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物 Active JP7369989B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2019035709A JP7369989B2 (ja) 2019-02-28 2019-02-28 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物
US17/434,331 US12404293B2 (en) 2019-02-28 2020-02-25 Method for producing glycan, building block for gylican synthesis, and compound
EP20763290.2A EP3932930A4 (en) 2019-02-28 2020-02-25 PROCESS FOR MAKING A SUGAR CHAIN, BUILDING BLOCK FOR SUGAR CHAIN SYNTHESIS AND CONNECTION
PCT/JP2020/007365 WO2020175440A1 (ja) 2019-02-28 2020-02-25 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2019035709A JP7369989B2 (ja) 2019-02-28 2019-02-28 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物

Publications (3)

Publication Number Publication Date
JP2020138931A JP2020138931A (ja) 2020-09-03
JP2020138931A5 JP2020138931A5 (enExample) 2022-03-03
JP7369989B2 true JP7369989B2 (ja) 2023-10-27

Family

ID=72240027

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019035709A Active JP7369989B2 (ja) 2019-02-28 2019-02-28 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物

Country Status (4)

Country Link
US (1) US12404293B2 (enExample)
EP (1) EP3932930A4 (enExample)
JP (1) JP7369989B2 (enExample)
WO (1) WO2020175440A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7670272B2 (ja) * 2021-09-22 2025-04-30 国立大学法人鳥取大学 環状オリゴ糖の製造方法、環状オリゴ糖および包接剤

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017165725A (ja) 2016-03-09 2017-09-21 国立大学法人鳥取大学 糖の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11072626B2 (en) * 2017-10-11 2021-07-27 Bristol-Myers Squibb Company Small molecule inhibitors of Galectin-3

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017165725A (ja) 2016-03-09 2017-09-21 国立大学法人鳥取大学 糖の製造方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
NOKAMI, T. et al.，Automated Electrochemical Assembly of the Protected Potential TMG-chitotriomycin Precursor Based on，Organic Letters，2015年，17(6)，pp. 1525-1528，DOI : 10.1021/acs.orglett.5b00406
NOKAMI, T. et al.，Automated Solution-Phase Synthesis of Oligosaccharides via Iterative Electrochemical Assembly of Thi，Organic Letters，2013年，15(17)，pp. 4520-4523，DOI : 10.1021/ol402034g
ZHANG, P. et al.，Total synthesis of LeA-LacNAc pentasaccharide as a ligand for Clostridium difficile toxin A，Organic & Biomolecular Chemistry，2010年，8(1)，pp. 128-136，DOI :10.1039/b914193f
野上敏材ら，特集：有機電解合成の最先端 ３．電解グリコシル化反応を利用したオリゴ糖自動合成システムの開発，Electrochemistry，2015年，83(6)，pp. 472-476

Also Published As

Publication number Publication date
EP3932930A1 (en) 2022-01-05
US12404293B2 (en) 2025-09-02
WO2020175440A1 (ja) 2020-09-03
JP2020138931A (ja) 2020-09-03
EP3932930A4 (en) 2022-12-14
US20230143273A1 (en) 2023-05-11

Similar Documents

Publication Publication Date Title
JP2023508985A (ja) 結晶性及び液晶性２５－ヒドロキシ－コレスタ－５－エン－３－硫酸ナトリウム、並びにその調製方法
JP7369989B2 (ja) 糖鎖の製造方法、糖鎖合成用のビルディングブロックおよび化合物
JP6981639B2 (ja) 糖の製造方法
JP4253858B2 (ja) フラーレン誘導体およびその製造方法
WO2010104192A1 (ja) オリゴアミノ糖化合物
CN110156848B (zh) 一种高抗凝活性化合物及其制备方法和应用
JPH04300879A (ja) Ｌ−タロピラノシド誘導体の製造方法
JP2629852B2 (ja) グリコシル化合物の製造方法
AU680047B2 (en) Ganglioside GM3 derivative having fluorinated ceramide moiety
CN112661802A (zh) 一种3′-甲氧基鸟苷的合成方法
CN116715704A (zh) 基于点击化学的软骨素寡糖及其制备方法
JP7417930B2 (ja) 糖鎖の製造方法
JP4518910B2 (ja) 分枝鎖型グリセロ化合物
CN120829376A (zh) 一种含有亚砜基团的对称二硫醚化合物及其在糖苷化反应中的应用
JPH04500677A (ja) モノ―またはポリヒドロキシル化された分子のヒドロキシル化されたサイトを置換することによる新規なジチオカルバミン酸エステルの特殊な合成方法と、この方法によって得られた製品と、その応用
WO2022191312A1 (ja) 新規な脱アルコキシフェニル化反応
JP4224429B2 (ja) スルホキノボシルアシルグリセロール
DK166212B (da) Fremgangsmaade til fremstilling af hydroxylgruppefrie o-alkylerede glycosylfluorider
JPH09241288A (ja) グリコシル化合物の立体選択的な製造方法
CN113372376A (zh) 一种坦西莫司中间体化合物ⅷ
JPH08246179A (ja) グリコシル化合物の製造方法
JP3998074B2 (ja) ポドフィロトキシンの脱メチル化方法
JPH10298193A (ja) 硫酸化オリゴ糖化合物及びその中間体並びに該硫酸化オリゴ糖化合物の製造方法
JPWO2014125967A1 (ja) ３，６−Ｏ−架橋ピラノース化合物及びα−Ｏ−ピラノシドの製造方法
JP2000143686A (ja) 硫酸化オリゴ糖化合物

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220222

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220222

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230228

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230421

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230628

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230919

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20231006

R150 Certificate of patent or registration of utility model

Ref document number: 7369989

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150