JP7369113B2 - 癌胎児性抗原結合タンパク質、関連する化合物および方法 - Google Patents

癌胎児性抗原結合タンパク質、関連する化合物および方法 Download PDF

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JP7369113B2
JP7369113B2 JP2020503056A JP2020503056A JP7369113B2 JP 7369113 B2 JP7369113 B2 JP 7369113B2 JP 2020503056 A JP2020503056 A JP 2020503056A JP 2020503056 A JP2020503056 A JP 2020503056A JP 7369113 B2 JP7369113 B2 JP 7369113B2
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amino acid
seq
acid sequence
binding domain
polypeptide
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JP2020530770A (ja
JP2020530770A5 (OSRAM
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ビアンヴニュ，デビッド
ヘルナンデス－ホヨス，ガブリエラ
ミッシャー，リンダ
ミッシェル，ダニエル
フリッツェル，サラ
ヴァラス，ローラ
エルマーク，ピーター
サール，アンナ
フュルブリング，クリスティーナ
シャンツ，ローラ フォン
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アプティーボ リサーチ アンド デベロップメント エルエルシー
アリゲーター・バイオサイエンス・アーベー
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2020503056A 2017-07-20 2018-07-20 癌胎児性抗原結合タンパク質、関連する化合物および方法 Active JP7369113B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762535107P 2017-07-20 2017-07-20
US62/535,107 2017-07-20
US201762575820P 2017-10-23 2017-10-23
US62/575,820 2017-10-23
US201862648072P 2018-03-26 2018-03-26
US62/648,072 2018-03-26
PCT/EP2018/069850 WO2019016402A1 (en) 2017-07-20 2018-07-20 BINDING PROTEINS BINDING AT 5T4 AND 4-1BB, COMPOSITIONS AND METHODS RELATED THERETO

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JP2020530770A JP2020530770A (ja) 2020-10-29
JP2020530770A5 JP2020530770A5 (OSRAM) 2021-08-26
JP7369113B2 true JP7369113B2 (ja) 2023-10-25

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US (3) US11725060B2 (OSRAM)
EP (1) EP3655439A1 (OSRAM)
JP (1) JP7369113B2 (OSRAM)
KR (1) KR102649757B1 (OSRAM)
CN (1) CN111148763B (OSRAM)
AU (1) AU2018304585B2 (OSRAM)
BR (1) BR112020001180A2 (OSRAM)
CA (1) CA3070272A1 (OSRAM)
CO (1) CO2020001654A2 (OSRAM)
IL (1) IL272103B2 (OSRAM)
MX (1) MX2020000583A (OSRAM)
NZ (1) NZ761636A (OSRAM)
PH (1) PH12020500137A1 (OSRAM)
SG (1) SG11202000503QA (OSRAM)
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US11725060B2 (en) * 2017-07-20 2023-08-15 Aptevo Reserch and Development LLC Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods
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CA3147423A1 (en) * 2019-07-26 2021-02-04 Abl Bio Inc. Anti-her2/anti-4-1bb bispecific antibody and use thereof
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EP4013506A1 (en) * 2019-08-12 2022-06-22 Aptevo Research and Development LLC 4-1bb and ox40 binding proteins and related compositions and methods, antibodies against 4-1bb, antibodies against ox40
TWI792371B (zh) * 2020-06-30 2023-02-11 大陸商諾納生物（蘇州）有限公司 一種4-1bb結合蛋白及其應用
EP4297786A4 (en) * 2021-02-23 2025-01-22 Pandion Operations, Inc. PD-1 ANTIBODIES, POLYPEPTIDES AND USES THEREOF
CN117769432A (zh) * 2021-05-28 2024-03-26 希融医疗公司 针对muc1-c/胞外结构域（muc1-c/ecd）的多特异性抗体构建体

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