JP7361720B2 - がんの治療のためのｋｒａｓ ｇ１２ｃ阻害剤 - Google Patents

がんの治療のためのｋｒａｓ ｇ１２ｃ阻害剤 Download PDF

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JP7361720B2
JP7361720B2 JP2020560375A JP2020560375A JP7361720B2 JP 7361720 B2 JP7361720 B2 JP 7361720B2 JP 2020560375 A JP2020560375 A JP 2020560375A JP 2020560375 A JP2020560375 A JP 2020560375A JP 7361720 B2 JP7361720 B2 JP 7361720B2
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JPWO2019217691A5 (https=
JP2021522281A (ja
JP2021522281A5 (https=
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ミナッチ，アナ・エレナ
ロウ，ジョナサン・ディー
ブルツ，ライアン・ポール
ランマン，ブライアン・アラン
シー，ビクター・ジェイ
バートバーガー，マイケル・ディー
チュウ－モイアー，マーガレット
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アムジエン・インコーポレーテツド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2020560375A 2018-05-10 2019-05-09 がんの治療のためのｋｒａｓ ｇ１２ｃ阻害剤 Active JP7361720B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862669723P 2018-05-10 2018-05-10
US62/669,723 2018-05-10
PCT/US2019/031535 WO2019217691A1 (en) 2018-05-10 2019-05-09 Kras g12c inhibitors for the treatment of cancer

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JP2021522281A JP2021522281A (ja) 2021-08-30
JPWO2019217691A5 JPWO2019217691A5 (https=) 2022-05-11
JP2021522281A5 JP2021522281A5 (https=) 2022-05-11
JP7361720B2 true JP7361720B2 (ja) 2023-10-16

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US (1) US10988485B2 (https=)
EP (1) EP3790886B1 (https=)
JP (1) JP7361720B2 (https=)
AU (1) AU2019265822B2 (https=)
CA (1) CA3099045A1 (https=)
ES (1) ES2986917T3 (https=)
MA (1) MA52564A (https=)
MX (1) MX2020011907A (https=)
WO (1) WO2019217691A1 (https=)

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