JP7353623B2 - 粒子分別装置及び粒子分別方法 - Google Patents

粒子分別装置及び粒子分別方法 Download PDF

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JP7353623B2
JP7353623B2 JP2019143443A JP2019143443A JP7353623B2 JP 7353623 B2 JP7353623 B2 JP 7353623B2 JP 2019143443 A JP2019143443 A JP 2019143443A JP 2019143443 A JP2019143443 A JP 2019143443A JP 7353623 B2 JP7353623 B2 JP 7353623B2
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droplet
jet flow
final
feature amount
satellite
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JP2021025866A5 (enExample
JP2021025866A (ja
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昌彦 神田
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ALLIED FLOW INC.
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ALLIED FLOW INC.
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Priority to US16/717,431 priority patent/US11492586B2/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C3/00—Separating dispersed particles from gases or vapour, e.g. air, by electrostatic effect
    • B03C3/34—Constructional details or accessories or operation thereof
    • B03C3/38—Particle charging or ionising stations, e.g. using electric discharge, radioactive radiation or flames
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/144—Imaging characterised by its optical setup
    • G01N2015/1443—Auxiliary imaging

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Particle Formation And Scattering Control In Inkjet Printers (AREA)
JP2019143443A 2019-08-05 2019-08-05 粒子分別装置及び粒子分別方法 Active JP7353623B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2019143443A JP7353623B2 (ja) 2019-08-05 2019-08-05 粒子分別装置及び粒子分別方法
US16/717,431 US11492586B2 (en) 2019-08-05 2019-12-17 Particle sorting apparatus and particle sorting method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2019143443A JP7353623B2 (ja) 2019-08-05 2019-08-05 粒子分別装置及び粒子分別方法

Publications (3)

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JP2021025866A JP2021025866A (ja) 2021-02-22
JP2021025866A5 JP2021025866A5 (enExample) 2022-07-05
JP7353623B2 true JP7353623B2 (ja) 2023-10-02

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Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230273108A1 (en) * 2020-07-28 2023-08-31 Sony Group Corporation Microparticle analysis device, microparticle sorting system, and microparticle analysis method
WO2022209859A1 (ja) * 2021-03-30 2022-10-06 ソニーグループ株式会社 粒子分析装置及び粒子分析方法
WO2023218986A1 (ja) * 2022-05-13 2023-11-16 ソニーグループ株式会社 液滴分取システム、液滴分取方法、及び液滴分取プログラム

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006292769A (ja) 2006-06-13 2006-10-26 Bay Bioscience Kk 生物学的粒子をソーティングする装置及び方法
JP2012137507A (ja) 1998-02-27 2012-07-19 Beckman Coulter Inc フローサイトメトリーのための方法および装置
WO2014115409A1 (ja) 2013-01-28 2014-07-31 ソニー株式会社 微小粒子分取装置、微小粒子分取方法及びプログラム
JP2017122734A (ja) 2017-03-02 2017-07-13 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
JP2019063798A (ja) 2018-12-04 2019-04-25 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム

Family Cites Families (13)

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US5700692A (en) 1994-09-27 1997-12-23 Becton Dickinson And Company Flow sorter with video-regulated droplet spacing
US6372506B1 (en) 1999-07-02 2002-04-16 Becton, Dickinson And Company Apparatus and method for verifying drop delay in a flow cytometer
US6941005B2 (en) 2002-11-01 2005-09-06 Coulter International Corp. Monitoring and control of droplet sorting
JP4304120B2 (ja) * 2004-04-30 2009-07-29 ベイバイオサイエンス株式会社 生物学的粒子をソーティングする装置及び方法
ES2644279T3 (es) 2011-04-29 2017-11-28 Becton Dickinson And Company Método y sistema clasificador de células
JP5924077B2 (ja) * 2012-03-30 2016-05-25 ソニー株式会社 微小粒子分取装置及び微小粒子分取装置における軌道方向判定方法
US9087371B2 (en) 2012-03-30 2015-07-21 Sony Corporation Microparticle sorting device and method of optimizing fluid stream therein
CN104487820B (zh) 2012-06-07 2018-03-09 生物辐射实验室股份有限公司 流式细胞计数的自动化且准确液滴延迟
EP3017288B1 (en) 2013-08-16 2020-10-07 Bio-rad Laboratories, Inc. Timing and/or phase adjustment of the charging of drops from a fluid stream in a flow cytometer
JP6102783B2 (ja) 2014-02-14 2017-03-29 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
JP6657625B2 (ja) * 2014-09-05 2020-03-04 ソニー株式会社 液滴分取装置、液滴分取方法及びプログラム
JP6707257B2 (ja) 2016-05-06 2020-06-10 アライドフロー株式会社 処理装置
US10466158B2 (en) * 2017-04-11 2019-11-05 Sony Corporation Microparticle sorting apparatus and delay time determination method

Patent Citations (6)

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Publication number Priority date Publication date Assignee Title
JP2012137507A (ja) 1998-02-27 2012-07-19 Beckman Coulter Inc フローサイトメトリーのための方法および装置
JP2006292769A (ja) 2006-06-13 2006-10-26 Bay Bioscience Kk 生物学的粒子をソーティングする装置及び方法
WO2014115409A1 (ja) 2013-01-28 2014-07-31 ソニー株式会社 微小粒子分取装置、微小粒子分取方法及びプログラム
US20150068957A1 (en) 2013-01-28 2015-03-12 Sony Corporation Microparticle sorting device, and method and program for sorting microparticles
JP2017122734A (ja) 2017-03-02 2017-07-13 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム
JP2019063798A (ja) 2018-12-04 2019-04-25 ソニー株式会社 粒子分取装置、粒子分取方法及びプログラム

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US20210039111A1 (en) 2021-02-11
JP2021025866A (ja) 2021-02-22

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