JP7352901B2 - 腫瘍成長を阻害するための材料および方法 - Google Patents

腫瘍成長を阻害するための材料および方法 Download PDF

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Publication number
JP7352901B2
JP7352901B2 JP2020519131A JP2020519131A JP7352901B2 JP 7352901 B2 JP7352901 B2 JP 7352901B2 JP 2020519131 A JP2020519131 A JP 2020519131A JP 2020519131 A JP2020519131 A JP 2020519131A JP 7352901 B2 JP7352901 B2 JP 7352901B2
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cancer
composition
amino acids
cancer cells
combination
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Japanese (ja)
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JP2020536096A5 (enExample
JP2020536096A (ja
Inventor
ビドヤサガー，サダシバン
グプタ，レシュ
ガット，ステフェン
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Entrinsic LLC
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Entrinsic LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2020519131A 2017-10-02 2018-10-02 腫瘍成長を阻害するための材料および方法 Active JP7352901B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023144987A JP2023171755A (ja) 2017-10-02 2023-09-07 腫瘍成長を阻害するための材料および方法

Applications Claiming Priority (3)

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US201762566787P 2017-10-02 2017-10-02
US62/566,787 2017-10-02
PCT/US2018/054015 WO2019070750A1 (en) 2017-10-02 2018-10-02 MATERIALS AND METHODS FOR INHIBITING TUMOR GROWTH

Related Child Applications (1)

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JP2023144987A Division JP2023171755A (ja) 2017-10-02 2023-09-07 腫瘍成長を阻害するための材料および方法

Publications (3)

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JP2020536096A JP2020536096A (ja) 2020-12-10
JP2020536096A5 JP2020536096A5 (enExample) 2021-11-11
JP7352901B2 true JP7352901B2 (ja) 2023-09-29

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JP2020519131A Active JP7352901B2 (ja) 2017-10-02 2018-10-02 腫瘍成長を阻害するための材料および方法
JP2023144987A Pending JP2023171755A (ja) 2017-10-02 2023-09-07 腫瘍成長を阻害するための材料および方法

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Country Link
US (1) US12109191B2 (enExample)
EP (1) EP3691628A1 (enExample)
JP (2) JP7352901B2 (enExample)
KR (1) KR102709096B1 (enExample)
CN (2) CN111417391B (enExample)
CA (1) CA3078335A1 (enExample)
WO (1) WO2019070750A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201700087359A1 (it) 2017-07-28 2019-01-28 Professional Dietetics Spa Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale
US12310936B2 (en) * 2018-05-22 2025-05-27 Seleq Oy Pharmaceutical compositions for the treatment of cancer
IT201800006725A1 (it) 2018-06-27 2019-12-27 Composizioni comprendenti aminoacidi per l'uso nella prevenzione e nel trattamento di malattie epatiche
IT202000000454A1 (it) * 2020-01-13 2021-07-13 Professional Dietetics Spa Composizioni comprendenti amino acidi per la prevenzione e il trattamento del cancro
IT202000000442A1 (it) 2020-01-13 2021-07-13 Professional Dietetics Spa Composizioni comprendenti amino acidi per l'uso nella prevenzione e nel trattamento di effetti collaterali della chemioterapia
CN115697301A (zh) * 2020-05-29 2023-02-03 佛罗里达大学研究基金会公司 用于治疗急性呼吸窘迫综合征、哮喘或变应性鼻炎的制剂和方法
CN115192564B (zh) * 2022-05-23 2023-11-17 四川大学华西医院 一种苯丙氨酸衍生物、药物组合物及其在肿瘤治疗中的应用
US11878073B1 (en) 2022-09-20 2024-01-23 Entrinsic, LLC Generation of hydration-targeted formulations and methods of use therein

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006834A1 (en) 1991-10-07 1993-04-15 Otsuka Pharmaceutical Factory, Inc. Enteral preparation for cancer therapy
JP2005097280A (ja) 2003-08-27 2005-04-14 Aaku Giken:Kk 抗腫瘍活性剤
WO2017053328A1 (en) 2015-09-21 2017-03-30 The Board Of Trustees Of The Leland Stanford Junior University Nutritional treatment for cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
JPH01301619A (ja) * 1988-05-30 1989-12-05 Otsuka Pharmaceut Factory Inc 癌用アミノ酸製剤
JPH0368514A (ja) 1989-08-09 1991-03-25 Morishita Pharmaceut Co Ltd 癌用アミノ酸製剤
WO1993006934A1 (en) 1991-09-30 1993-04-15 Devtech Labs, Inc. Electrostatic separation of plastic materials
US5658895A (en) 1991-10-07 1997-08-19 Otsuka Pharmaceutical Factory, Inc. Anticancer enteral feeding composition
JP3429327B2 (ja) 1992-07-20 2003-07-22 味の素ファルマ株式会社 癌用アミノ酸輸液剤
JPH06256184A (ja) 1993-03-05 1994-09-13 Morishita Roussel Kk 癌患者用アミノ酸製剤
US20050176807A1 (en) * 2004-02-09 2005-08-11 Friesen Kim G. Composition and method for use in cartilage affecting conditions
EP3698780A1 (en) * 2004-08-09 2020-08-26 Enrique Melendez Hevia Glycine as a diet supplement for use in the prevention and/or treatment of an infectious disease caused by a virus in a human in the need of promoting the synthesis of collagen
KR102069790B1 (ko) 2010-09-24 2020-01-23 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 위장 기능을 증진시키기 위한 물질 및 방법
EP3016531A4 (en) * 2013-07-01 2017-05-10 The Trustees Of Princeton University Dietary supplements and composition for treating cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006834A1 (en) 1991-10-07 1993-04-15 Otsuka Pharmaceutical Factory, Inc. Enteral preparation for cancer therapy
JP2005097280A (ja) 2003-08-27 2005-04-14 Aaku Giken:Kk 抗腫瘍活性剤
WO2017053328A1 (en) 2015-09-21 2017-03-30 The Board Of Trustees Of The Leland Stanford Junior University Nutritional treatment for cancer

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Publication number Publication date
US20200323820A1 (en) 2020-10-15
EP3691628A1 (en) 2020-08-12
JP2020536096A (ja) 2020-12-10
WO2019070750A1 (en) 2019-04-11
CN111417391A (zh) 2020-07-14
CN118078810A (zh) 2024-05-28
JP2023171755A (ja) 2023-12-05
US12109191B2 (en) 2024-10-08
KR102709096B1 (ko) 2024-09-23
CN111417391B (zh) 2024-06-18
CA3078335A1 (en) 2019-04-11
KR20200060492A (ko) 2020-05-29

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