JP7328465B2 - 演算装置、制御装置、培養システム、及び培養システムの設計方法 - Google Patents

演算装置、制御装置、培養システム、及び培養システムの設計方法 Download PDF

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JP7328465B2
JP7328465B2 JP2022575344A JP2022575344A JP7328465B2 JP 7328465 B2 JP7328465 B2 JP 7328465B2 JP 2022575344 A JP2022575344 A JP 2022575344A JP 2022575344 A JP2022575344 A JP 2022575344A JP 7328465 B2 JP7328465 B2 JP 7328465B2
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culture
value
control
oxygen supply
culture tank
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JPWO2023021571A5 (https=
JPWO2023021571A1 (https=
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亘 早坂
奈津美 山田
直樹 田原
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JGC Corp
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JGC Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Computer Hardware Design (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
JP2022575344A 2021-08-17 2021-08-17 演算装置、制御装置、培養システム、及び培養システムの設計方法 Active JP7328465B2 (ja)

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PCT/JP2021/029994 WO2023021571A1 (ja) 2021-08-17 2021-08-17 演算装置、制御装置、培養システム、及び培養システムの設計方法

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JPWO2023021571A1 JPWO2023021571A1 (https=) 2023-02-23
JPWO2023021571A5 JPWO2023021571A5 (https=) 2023-07-26
JP7328465B2 true JP7328465B2 (ja) 2023-08-16

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US (1) US11859166B2 (https=)
EP (1) EP4389868A1 (https=)
JP (1) JP7328465B2 (https=)
TW (1) TWI822173B (https=)
WO (1) WO2023021571A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025042031A1 (ko) * 2023-08-23 2025-02-27 임성혁 미생물의 균일생장을 제어할 수 있는 스마트 팜 시스템

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006296423A (ja) 2005-03-24 2006-11-02 Hitachi Ltd 培養槽の制御装置及び培養装置
JP2019129726A (ja) 2018-01-29 2019-08-08 長瀬産業株式会社 Ｏｔｒシミュレータ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07203945A (ja) * 1994-01-12 1995-08-08 Hitachi Ltd 生体の細胞の培養装置
US7771988B2 (en) * 2005-03-24 2010-08-10 Hitachi, Ltd. Control device for fermenter
JP5001659B2 (ja) 2007-01-04 2012-08-15 住重関西施設管理株式会社 溶存酸素量制御装置
CA2946312A1 (en) * 2014-04-23 2015-10-29 Juno Therapeutics, Inc. Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy
CN111699240A (zh) * 2018-01-17 2020-09-22 生命技术公司 用于细胞培养缩放的系统和方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006296423A (ja) 2005-03-24 2006-11-02 Hitachi Ltd 培養槽の制御装置及び培養装置
JP2019129726A (ja) 2018-01-29 2019-08-08 長瀬産業株式会社 Ｏｔｒシミュレータ

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHATZIDOUKAS, C. et al.，Development of a structured dynamic model for the production of polyhydroxybutyrate (PHB) in Azohydromonas lata cultures，Biochemical Engineering Journal，2013年，Vol.71，p.72-80
HEWITT, C. J. et al.，The Scale-up of microbial batch and fed-batch fermentation processes，Advances in Applied Microbiology，2007年，Vol.62，p.105-135
SKRJANC, I.，Adaptive Supervisory Predictive Control of a Hybrid Fed-Batch Reactor with Slow Actuator，Industrial & Engineering Chemistry Research，2007年，Vol.46，p.8050-8057
田原直樹，抗体医薬製造の核となるバイオ医薬品製造プロセス技術／バイオエンジニアリング技術，PHARM TECH JAPAN，2012年，Vol.28, No.9，p.49-58
田原直樹、他，動物細胞培養用バイオリアクター「バーサスリアクター（登録商標）」の開発と実用化，PHARM TECH JAPAN，2015年，Vol.31, No.14，p.25-33

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Publication number Publication date
US20230348837A1 (en) 2023-11-02
TWI822173B (zh) 2023-11-11
WO2023021571A1 (ja) 2023-02-23
TW202308949A (zh) 2023-03-01
US11859166B2 (en) 2024-01-02
JPWO2023021571A1 (https=) 2023-02-23
EP4389868A1 (en) 2024-06-26

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