JP7321709B2 - がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン - Google Patents

がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン Download PDF

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JP7321709B2
JP7321709B2 JP2018563076A JP2018563076A JP7321709B2 JP 7321709 B2 JP7321709 B2 JP 7321709B2 JP 2018563076 A JP2018563076 A JP 2018563076A JP 2018563076 A JP2018563076 A JP 2018563076A JP 7321709 B2 JP7321709 B2 JP 7321709B2
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ガウダーナック，グスタフ
トルネス，アウドゥン
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ウルティモバックス エーエス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001148—Regulators of development
    • A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A61K39/001157—Telomerase or TERT [telomerase reverse transcriptase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Organic Chemistry (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2018563076A 2016-06-02 2017-06-02 がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン Active JP7321709B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022132995A JP2022171684A (ja) 2016-06-02 2022-08-24 がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16172760 2016-06-02
EP16172760.7 2016-06-02
PCT/EP2017/063589 WO2017207814A1 (en) 2016-06-02 2017-06-02 A vaccine in combination with an immune checkpoint inhibitor for use in treating cancer

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JP2022132995A Division JP2022171684A (ja) 2016-06-02 2022-08-24 がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン

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JP2019517508A JP2019517508A (ja) 2019-06-24
JP2019517508A5 JP2019517508A5 (enExample) 2020-07-16
JP7321709B2 true JP7321709B2 (ja) 2023-08-07

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JP2022132995A Pending JP2022171684A (ja) 2016-06-02 2022-08-24 がんの治療における使用のための免疫チェックポイント阻害剤と組み合わされたワクチン

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US (2) US11419927B2 (enExample)
EP (2) EP3463436B1 (enExample)
JP (2) JP7321709B2 (enExample)
AU (1) AU2017275782B2 (enExample)
CA (1) CA3026172A1 (enExample)
CY (1) CY1126489T1 (enExample)
DK (1) DK3463436T3 (enExample)
ES (1) ES2965957T3 (enExample)
FI (1) FI3463436T3 (enExample)
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LT (1) LT3463436T (enExample)
PL (1) PL3463436T3 (enExample)
PT (1) PT3463436T (enExample)
RS (1) RS65007B1 (enExample)
SI (1) SI3463436T1 (enExample)
WO (1) WO2017207814A1 (enExample)

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RU2581800C2 (ru) 2010-02-16 2016-04-20 Ультимовакс Ас Полипептиды
PT3463436T (pt) 2016-06-02 2023-12-28 Ultimovacs As Uma vacina em combinação com um inibidor de ponto de verificação imune para utilização no tratamento do cancro
GB201803178D0 (en) * 2018-02-27 2018-04-11 Univ Oslo Hf Specific binding molecules for htert
TWI805792B (zh) * 2018-06-29 2023-06-21 日商大鵬藥品工業股份有限公司 抗腫瘤劑及其評估方法
WO2022258794A2 (en) 2021-06-09 2022-12-15 Ultimovacs Ab A conjugate
WO2024083867A1 (en) 2022-10-17 2024-04-25 Ultimovacs Asa Biomarker
WO2024126737A1 (en) 2022-12-14 2024-06-20 Ultimovacs Ab A core and a conjugate
WO2024126758A2 (en) 2022-12-14 2024-06-20 Ultimovacs Ab A nucleic acid molecule and a chimeric polypeptide

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RS65007B1 (sr) 2024-01-31
EP4253419A2 (en) 2023-10-04
HRP20231650T1 (hr) 2024-05-10
SI3463436T1 (sl) 2024-02-29
EP4253419A3 (en) 2024-05-22
ES2965957T3 (es) 2024-04-17
JP2019517508A (ja) 2019-06-24
US20190247482A1 (en) 2019-08-15
JP2022171684A (ja) 2022-11-11
US20230049012A1 (en) 2023-02-16
EP3463436B1 (en) 2023-09-20
US12168045B2 (en) 2024-12-17
AU2017275782B2 (en) 2024-08-15
US11419927B2 (en) 2022-08-23
DK3463436T3 (da) 2023-12-18
CA3026172A1 (en) 2017-12-07
HUE065176T2 (hu) 2024-05-28
CY1126489T1 (el) 2026-02-25
PL3463436T3 (pl) 2024-03-04
WO2017207814A1 (en) 2017-12-07
LT3463436T (lt) 2024-01-25
FI3463436T3 (fi) 2023-12-04
EP3463436A1 (en) 2019-04-10
AU2017275782A1 (en) 2019-01-24
PT3463436T (pt) 2023-12-28

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