DK3463436T3 - Vaccine i kombination med en immuncheckpoint-hæmmer til anvendelse i cancerbehandling - Google Patents
Vaccine i kombination med en immuncheckpoint-hæmmer til anvendelse i cancerbehandling Download PDFInfo
- Publication number
- DK3463436T3 DK3463436T3 DK17729078.0T DK17729078T DK3463436T3 DK 3463436 T3 DK3463436 T3 DK 3463436T3 DK 17729078 T DK17729078 T DK 17729078T DK 3463436 T3 DK3463436 T3 DK 3463436T3
- Authority
- DK
- Denmark
- Prior art keywords
- vaccine
- cancer
- treatment
- combination
- immune checkpoint
- Prior art date
Links
- 229940076838 Immune checkpoint inhibitor Drugs 0.000 title 1
- 102000037984 Inhibitory immune checkpoint proteins Human genes 0.000 title 1
- 108091008026 Inhibitory immune checkpoint proteins Proteins 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 239000012274 immune-checkpoint protein inhibitor Substances 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
- A61K39/001157—Telomerase or TERT [telomerase reverse transcriptase]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001148—Regulators of development
- A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001154—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16172760 | 2016-06-02 | ||
PCT/EP2017/063589 WO2017207814A1 (en) | 2016-06-02 | 2017-06-02 | A vaccine in combination with an immune checkpoint inhibitor for use in treating cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3463436T3 true DK3463436T3 (da) | 2023-12-18 |
Family
ID=56132759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK17729078.0T DK3463436T3 (da) | 2016-06-02 | 2017-06-02 | Vaccine i kombination med en immuncheckpoint-hæmmer til anvendelse i cancerbehandling |
Country Status (15)
Country | Link |
---|---|
US (2) | US11419927B2 (da) |
EP (2) | EP3463436B1 (da) |
JP (2) | JP7321709B2 (da) |
AU (1) | AU2017275782A1 (da) |
CA (1) | CA3026172A1 (da) |
DK (1) | DK3463436T3 (da) |
ES (1) | ES2965957T3 (da) |
FI (1) | FI3463436T3 (da) |
HR (1) | HRP20231650T1 (da) |
LT (1) | LT3463436T (da) |
PL (1) | PL3463436T3 (da) |
PT (1) | PT3463436T (da) |
RS (1) | RS65007B1 (da) |
SI (1) | SI3463436T1 (da) |
WO (1) | WO2017207814A1 (da) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2536830B1 (en) | 2010-02-16 | 2019-07-17 | Ultimovacs AS | Polypeptides |
GB201803178D0 (en) * | 2018-02-27 | 2018-04-11 | Univ Oslo Hf | Specific binding molecules for htert |
US20210236613A1 (en) * | 2018-06-29 | 2021-08-05 | Taiho Pharmaceutical Co., Ltd. | Antitumor agent and evaluation method thereof |
EP4351634A2 (en) | 2021-06-09 | 2024-04-17 | Ultimovacs AB | A conjugate |
WO2024083867A1 (en) | 2022-10-17 | 2024-04-25 | Ultimovacs Asa | Biomarker |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6936704B1 (en) | 1999-08-23 | 2005-08-30 | Dana-Farber Cancer Institute, Inc. | Nucleic acids encoding costimulatory molecule B7-4 |
DK1234031T3 (da) | 1999-11-30 | 2017-07-03 | Mayo Foundation | B7-h1, et hidtil ukendt immunregulerende molekyle |
JP2005529873A (ja) | 2002-04-12 | 2005-10-06 | メダレックス インコーポレイテッド | Ctla−4抗体を使用した治療の方法 |
AU2003288675B2 (en) | 2002-12-23 | 2010-07-22 | Medimmune Limited | Antibodies against PD-1 and uses therefor |
CN109485727A (zh) | 2005-05-09 | 2019-03-19 | 小野药品工业株式会社 | 程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法 |
MX2007015942A (es) | 2005-07-01 | 2008-03-07 | Medarex Inc | Anticuerpos monoclonales humanos para ligandos 1 (pd-l1) de muerte programada. |
CA2647282A1 (en) | 2006-04-05 | 2007-10-11 | Pfizer Products Inc. | Ctla4 antibody combination therapy |
US8168757B2 (en) | 2008-03-12 | 2012-05-01 | Merck Sharp & Dohme Corp. | PD-1 binding proteins |
TWI686405B (zh) | 2008-12-09 | 2020-03-01 | 建南德克公司 | 抗pd-l1抗體及其於增進t細胞功能之用途 |
EP2536830B1 (en) | 2010-02-16 | 2019-07-17 | Ultimovacs AS | Polypeptides |
WO2012037551A2 (en) | 2010-09-17 | 2012-03-22 | Irx Therapeutics, Inc. | Primary cell-derived biologic and wt1 synthetic long peptide vaccine |
CA2883569A1 (en) | 2012-08-31 | 2014-03-06 | University Of Virginia Patent Foundation | Target peptides for immunotherapy and diagnostics |
GB201223386D0 (en) | 2012-12-24 | 2013-02-06 | Immune Targeting Systems Its Ltd | Vaccine |
SG11201506052PA (en) * | 2013-02-22 | 2015-09-29 | Curevac Gmbh | Combination of vaccination and inhibition of the pd-1 pathway |
KR20230062674A (ko) | 2013-03-15 | 2023-05-09 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 암 백신 및 이를 이용한 치료 방법 |
GB201315946D0 (en) | 2013-09-06 | 2013-10-23 | Immune Targeting Systems Its Ltd | Oncology vaccine |
WO2015037000A1 (en) | 2013-09-11 | 2015-03-19 | Compugen Ltd | Vstm5 polypeptides and uses thereof as a drug for treatment of cancer, infectious diseases and immune related diseases |
US20170035864A1 (en) | 2013-12-09 | 2017-02-09 | Bullet Biotechnology, Inc. | SPECIFIC VIRUS-LIKE PARTICLE-CpG OLIGONUCLEOTIDE VACCINES AND USES THEREOF |
CN106456724A (zh) | 2013-12-20 | 2017-02-22 | 博德研究所 | 使用新抗原疫苗的联合疗法 |
EP3088614B1 (en) | 2013-12-27 | 2021-08-25 | Xiamen Solex High-Tech Industries Co., Ltd. | Flush-mounted pre-embedded assembly |
CA2939093A1 (en) | 2014-02-14 | 2015-08-20 | Immune Design Corp. | Immunotherapy of cancer through combination of local and systemic immune stimulation |
US10933106B2 (en) | 2014-02-25 | 2021-03-02 | Deutsches Krebsforschungszentrum | RNA viruses for immunovirotherapy |
JP2017515841A (ja) | 2014-05-13 | 2017-06-15 | バヴァリアン・ノルディック・アクティーゼルスカブ | 腫瘍抗原を発現するポックスウイルス及びtim−3に対するモノクローナル抗体を用いた癌治療のための併用療法 |
KR102499737B1 (ko) | 2014-05-13 | 2023-02-13 | 버베리안 노딕 에이/에스 | 종양 항원을 발현하는 재조합 폭스바이러스 및 면역 체크포인트 분자 길항제 또는 효현제로 암을 치료하기 위한 복합 요법 |
WO2016004213A2 (en) | 2014-07-01 | 2016-01-07 | Vicus Therapeutics, Llc | Hydrogels for treating and ameliorating cancers and potentiating the immune system and methods of making and using them |
EP3166646A4 (en) | 2014-07-07 | 2018-03-07 | Duke University | Vaccines against an oncogenic isoform of her2 (erbb2) and methods of using the same |
EP3166630A4 (en) | 2014-07-07 | 2018-03-28 | Duke University | Vaccines against an oncogenic isoform of esr1 and methods of using the same |
CN106715458A (zh) | 2014-07-18 | 2017-05-24 | 华盛顿大学 | 癌症疫苗组合物及其使用方法 |
AU2015289449A1 (en) | 2014-07-18 | 2017-02-09 | Advaxis, Inc. | Listeria-based immunogenic compositions for eliciting anti-tumor responses |
WO2016025645A1 (en) | 2014-08-12 | 2016-02-18 | Massachusetts Institute Of Technology | Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker |
AU2015334468B2 (en) | 2014-10-23 | 2021-06-17 | Institut Gustave Roussy | Methods and products for modulating microbiota composition for improving the efficacy of a cancer treatment with an immune checkpoint blocker |
US11236139B2 (en) | 2014-11-05 | 2022-02-01 | The Regents Of The University Of California | Combination immunotherapy |
NL2017270B1 (en) | 2016-08-02 | 2018-02-09 | Aduro Biotech Holdings Europe B V | New anti-hCTLA-4 antibodies |
-
2017
- 2017-06-02 PT PT177290780T patent/PT3463436T/pt unknown
- 2017-06-02 EP EP17729078.0A patent/EP3463436B1/en active Active
- 2017-06-02 PL PL17729078.0T patent/PL3463436T3/pl unknown
- 2017-06-02 AU AU2017275782A patent/AU2017275782A1/en active Pending
- 2017-06-02 CA CA3026172A patent/CA3026172A1/en active Pending
- 2017-06-02 JP JP2018563076A patent/JP7321709B2/ja active Active
- 2017-06-02 RS RS20231231A patent/RS65007B1/sr unknown
- 2017-06-02 SI SI201731461T patent/SI3463436T1/sl unknown
- 2017-06-02 DK DK17729078.0T patent/DK3463436T3/da active
- 2017-06-02 ES ES17729078T patent/ES2965957T3/es active Active
- 2017-06-02 WO PCT/EP2017/063589 patent/WO2017207814A1/en active Application Filing
- 2017-06-02 US US16/306,352 patent/US11419927B2/en active Active
- 2017-06-02 EP EP23178501.5A patent/EP4253419A3/en active Pending
- 2017-06-02 FI FIEP17729078.0T patent/FI3463436T3/fi active
- 2017-06-02 LT LTEPPCT/EP2017/063589T patent/LT3463436T/lt unknown
- 2017-06-02 HR HRP20231650TT patent/HRP20231650T1/hr unknown
-
2022
- 2022-08-09 US US17/818,584 patent/US20230049012A1/en active Pending
- 2022-08-24 JP JP2022132995A patent/JP2022171684A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FI3463436T3 (fi) | 2023-12-04 |
US11419927B2 (en) | 2022-08-23 |
CA3026172A1 (en) | 2017-12-07 |
SI3463436T1 (sl) | 2024-02-29 |
JP2019517508A (ja) | 2019-06-24 |
PL3463436T3 (pl) | 2024-03-04 |
JP2022171684A (ja) | 2022-11-11 |
PT3463436T (pt) | 2023-12-28 |
WO2017207814A1 (en) | 2017-12-07 |
JP7321709B2 (ja) | 2023-08-07 |
US20230049012A1 (en) | 2023-02-16 |
US20190247482A1 (en) | 2019-08-15 |
LT3463436T (lt) | 2024-01-25 |
ES2965957T3 (es) | 2024-04-17 |
EP3463436A1 (en) | 2019-04-10 |
EP4253419A3 (en) | 2024-05-22 |
HRP20231650T1 (hr) | 2024-05-10 |
AU2017275782A1 (en) | 2019-01-24 |
EP3463436B1 (en) | 2023-09-20 |
RS65007B1 (sr) | 2024-01-31 |
EP4253419A2 (en) | 2023-10-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL286282A (en) | Use of palinabolin in combination with immune checkpoint inhibitors | |
DK3331915T3 (da) | Immun-checkpoint-inhibitorer til anvendelse til behandling af blodbårne cancere | |
DK3500299T3 (da) | Kombination af zanubrutinib med et anti-CD20- eller et anti-PD-1-antistof til anvendelse i behandling af cancer | |
DK3535392T3 (da) | Immunologisk synlige celleoverfladevarianter til anvendelse i celleterapi | |
IL247841B (en) | Heterocyclic compounds in combination with immune barrier therapy for use in the treatment of disorders mediated by pi3k gamma | |
GB2548873B (en) | Use of Cannabidiol in the Treatment of SturgeWeber Syndrome | |
DK3277842T3 (da) | Fremgangsmåder til at behandle kræftpatienter med farnesyl-transferase-inhibitorer | |
IL265274A (en) | Combined treatment of antibody and checkpoint inhibitor | |
BR112017002511A2 (pt) | sistemas e métodos de almofada terapêutica | |
DK3481846T3 (da) | 11-substituerede 24-hydroxysteroler til anvendelse til behandling af nmda-relaterede tilstande | |
DK3197472T3 (da) | Rekombinante phe-frie proteiner til anvendelse i behandlingen af phenylketonuri | |
DK3463436T3 (da) | Vaccine i kombination med en immuncheckpoint-hæmmer til anvendelse i cancerbehandling | |
DK3182996T3 (da) | Fremgangsmåder til behandling af myelomatose med immunmodulatoriske forbindelser i kombination med antistoffer | |
HK1254954A1 (zh) | Lpt-723和免疫檢查點抑制劑組合物及其治療方法 | |
DK3532067T3 (da) | Liposomal formulering til anvendelse til behandling af cancer | |
DK3374497T3 (da) | Modificerede makrofager til anvendelse i behandlingen af kræft | |
DK3230318T3 (da) | Immune checkpoint-inhibitor-kombinationer | |
DK3253208T3 (da) | Kombinationsterapier til anvendelse i behandlingen af brystcancer | |
EA201891679A1 (ru) | Лечение рака онколитическим вирусом в комбинации с ингибитором контрольных точек | |
DK3149049T3 (da) | Il-22 til anvendelse til behandling af stofskiftesygdomme | |
DK3408265T3 (da) | Terapeutiske forbindelser | |
DK3293201T3 (da) | Kombinering af adenovirus og checkpoint-inhibitorer til behandling af cancer | |
DK2984184T3 (da) | Anvendelse af dnq eller dnq-87 i kombination med en parp1-inhibitor til behandlingen af cancer | |
IL266116A (en) | Anti-bag3 antibodies in combination with inhibitors of immune check-point for therapeutic use | |
DK3153511T3 (da) | 2-acylaminothiazolderivat til anvendelse i forebyggelsen eller behandlingen af blære- og urinvejssygdomme |