JP7316222B2 - 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法 - Google Patents

長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法 Download PDF

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JP7316222B2
JP7316222B2 JP2019563255A JP2019563255A JP7316222B2 JP 7316222 B2 JP7316222 B2 JP 7316222B2 JP 2019563255 A JP2019563255 A JP 2019563255A JP 2019563255 A JP2019563255 A JP 2019563255A JP 7316222 B2 JP7316222 B2 JP 7316222B2
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JP2020519676A (ja
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ピーター ベネディクト カーク，
ピン ジャン，
ペイウェン クオ ブリュワー，
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ネクター セラピューティクス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2086—IL-13 to IL-16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5443—IL-15
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7156—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interferons [IFN]

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  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2019563255A 2017-05-15 2018-05-15 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法 Active JP7316222B2 (ja)

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JP2023063333A JP7772733B2 (ja) 2017-05-15 2023-04-10 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法
JP2025076268A JP2025111770A (ja) 2017-05-15 2025-05-01 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法

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Application Number Priority Date Filing Date Title
US201762506494P 2017-05-15 2017-05-15
US62/506,494 2017-05-15
US201762536966P 2017-07-25 2017-07-25
US62/536,966 2017-07-25
US201762582186P 2017-11-06 2017-11-06
US62/582,186 2017-11-06
US201862648240P 2018-03-26 2018-03-26
US62/648,240 2018-03-26
PCT/US2018/032817 WO2018213341A1 (en) 2017-05-15 2018-05-15 Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods

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JP7316222B2 true JP7316222B2 (ja) 2023-07-27

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JP2023063333A Active JP7772733B2 (ja) 2017-05-15 2023-04-10 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法
JP2025076268A Pending JP2025111770A (ja) 2017-05-15 2025-05-01 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法

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JP2025076268A Pending JP2025111770A (ja) 2017-05-15 2025-05-01 長時間作用型インターロイキン－１５受容体作動薬並びに関連する免疫治療組成物及び方法

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US (2) US12036283B2 (enExample)
EP (1) EP3624827A4 (enExample)
JP (3) JP7316222B2 (enExample)
KR (2) KR20250057110A (enExample)
CN (2) CN111093688B (enExample)
AU (2) AU2018270926C1 (enExample)
CA (1) CA3060410A1 (enExample)
IL (2) IL318018A (enExample)
MX (2) MX2019013621A (enExample)
WO (1) WO2018213341A1 (enExample)

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Also Published As

Publication number Publication date
MX2024009988A (es) 2024-08-27
CN111093688B (zh) 2025-09-16
IL270634B1 (en) 2025-02-01
AU2018270926B2 (en) 2022-04-07
US20200078467A1 (en) 2020-03-12
KR20200003922A (ko) 2020-01-10
AU2018270926C1 (en) 2022-10-27
KR20250057110A (ko) 2025-04-28
JP7772733B2 (ja) 2025-11-18
CN119700941A (zh) 2025-03-28
EP3624827A1 (en) 2020-03-25
JP2020519676A (ja) 2020-07-02
US20240424115A1 (en) 2024-12-26
WO2018213341A1 (en) 2018-11-22
AU2018270926A1 (en) 2019-11-07
IL318018A (en) 2025-02-01
CA3060410A1 (en) 2018-11-22
JP2023082218A (ja) 2023-06-13
JP2025111770A (ja) 2025-07-30
EP3624827A4 (en) 2021-03-03
CN111093688A (zh) 2020-05-01
MX2019013621A (es) 2020-01-13
IL270634B2 (en) 2025-06-01
US12036283B2 (en) 2024-07-16
IL270634A (en) 2019-12-31
AU2022203691B2 (en) 2023-10-12
AU2022203691A1 (en) 2022-06-16
KR102798243B1 (ko) 2025-04-18

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