MX2019013621A - Agonistas del receptor de interleuquina-15 de accion prolongada y composiciones y metodos inmunoterapeuticos relacionados. - Google Patents
Agonistas del receptor de interleuquina-15 de accion prolongada y composiciones y metodos inmunoterapeuticos relacionados.Info
- Publication number
- MX2019013621A MX2019013621A MX2019013621A MX2019013621A MX2019013621A MX 2019013621 A MX2019013621 A MX 2019013621A MX 2019013621 A MX2019013621 A MX 2019013621A MX 2019013621 A MX2019013621 A MX 2019013621A MX 2019013621 A MX2019013621 A MX 2019013621A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- long
- receptor agonists
- immunotherapeutic compositions
- acting interleukin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2086—IL-13 to IL-16
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5443—IL-15
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7156—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
La presente divulgación proporciona un agonista del receptor de IL-15 de acción prolongada, composiciones relacionadas y métodos de preparación y uso, por ejemplo, en el tratamiento de afecciones que responden a la terapia efectiva para proporcionar, por ejemplo, actividad inmuno-sostenida y actividad antitumoral.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762506494P | 2017-05-15 | 2017-05-15 | |
US201762536966P | 2017-07-25 | 2017-07-25 | |
US201762582186P | 2017-11-06 | 2017-11-06 | |
US201862648240P | 2018-03-26 | 2018-03-26 | |
PCT/US2018/032817 WO2018213341A1 (en) | 2017-05-15 | 2018-05-15 | Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019013621A true MX2019013621A (es) | 2020-01-13 |
Family
ID=64274790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019013621A MX2019013621A (es) | 2017-05-15 | 2018-05-15 | Agonistas del receptor de interleuquina-15 de accion prolongada y composiciones y metodos inmunoterapeuticos relacionados. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20200078467A1 (es) |
EP (1) | EP3624827A4 (es) |
JP (2) | JP7316222B2 (es) |
KR (1) | KR20200003922A (es) |
CN (1) | CN111093688A (es) |
AU (2) | AU2018270926C1 (es) |
CA (1) | CA3060410A1 (es) |
MX (1) | MX2019013621A (es) |
WO (1) | WO2018213341A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3100007A1 (en) | 2018-05-14 | 2019-11-21 | Werewolf Therapeutics, Inc. | Activatable interleukin-2 polypeptides and methods of use thereof |
JP2021523741A (ja) | 2018-05-14 | 2021-09-09 | ウェアウルフ セラピューティクス, インコーポレイテッド | 活性化可能なインターロイキン12ポリペプチド及びその使用方法 |
CA3119049A1 (en) * | 2018-11-09 | 2020-05-14 | Nektar Therapeutics | Long-acting interleukin-15 receptor agonist in combination with another pharmacologically active agent |
WO2020206395A1 (en) * | 2019-04-05 | 2020-10-08 | Nektar Therapeutics | Method for enhancing cellular immunotherapy |
SG11202112541RA (en) | 2019-05-14 | 2021-12-30 | Werewolf Therapeutics Inc | Separation moieties and methods and use thereof |
MX2021014189A (es) | 2019-05-20 | 2022-01-06 | Cytune Pharma | Regimenes de dosificacion de agonistas de la il-2/il-15r?y para el tratamiento del cancer o enfermedades infecciosas. |
EP4232068A1 (en) | 2020-10-26 | 2023-08-30 | Cytune Pharma | IL-2/IL-15RBetaGamma AGONIST FOR TREATING NON-MELANOMA SKIN CANCER |
EP4232069A1 (en) | 2020-10-26 | 2023-08-30 | Cytune Pharma | Il-2/il-15rbetagamma agonist for treating squamous cell carcinoma |
KR20240024241A (ko) | 2021-06-23 | 2024-02-23 | 싸이튠 파마 | 인터루킨 15 변이체 |
KR20240043797A (ko) | 2021-08-13 | 2024-04-03 | 싸이튠 파마 | 암 치료용 IL-2/IL-15Rβγ 작용제와 항체-약물 접합체 조합 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010033240A2 (en) * | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
CN102145178B (zh) * | 2011-04-15 | 2012-09-26 | 北京凯因科技股份有限公司 | Peg化白介素15 |
MA39711A (fr) * | 2014-04-03 | 2015-10-08 | Nektar Therapeutics | Conjugués d'une fraction d'il-15 et d'un polymère |
EP3206713A4 (en) * | 2014-10-14 | 2018-06-27 | Armo Biosciences, Inc. | Interleukin-15 compositions and uses thereof |
JP7407511B2 (ja) * | 2015-10-08 | 2024-01-04 | ネクター セラピューティクス | IL-2Rβ選択的作動薬と長時間作用型IL-15作動薬との併用 |
-
2018
- 2018-05-15 KR KR1020197036787A patent/KR20200003922A/ko not_active Application Discontinuation
- 2018-05-15 JP JP2019563255A patent/JP7316222B2/ja active Active
- 2018-05-15 EP EP18803095.1A patent/EP3624827A4/en active Pending
- 2018-05-15 WO PCT/US2018/032817 patent/WO2018213341A1/en unknown
- 2018-05-15 AU AU2018270926A patent/AU2018270926C1/en active Active
- 2018-05-15 CN CN201880032373.3A patent/CN111093688A/zh active Pending
- 2018-05-15 US US16/613,757 patent/US20200078467A1/en active Pending
- 2018-05-15 CA CA3060410A patent/CA3060410A1/en active Pending
- 2018-05-15 MX MX2019013621A patent/MX2019013621A/es unknown
-
2022
- 2022-05-31 AU AU2022203691A patent/AU2022203691B2/en active Active
-
2023
- 2023-04-10 JP JP2023063333A patent/JP2023082218A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2018270926C1 (en) | 2022-10-27 |
KR20200003922A (ko) | 2020-01-10 |
JP2020519676A (ja) | 2020-07-02 |
AU2018270926B2 (en) | 2022-04-07 |
EP3624827A4 (en) | 2021-03-03 |
CN111093688A (zh) | 2020-05-01 |
AU2022203691A1 (en) | 2022-06-16 |
CA3060410A1 (en) | 2018-11-22 |
JP2023082218A (ja) | 2023-06-13 |
JP7316222B2 (ja) | 2023-07-27 |
WO2018213341A1 (en) | 2018-11-22 |
US20200078467A1 (en) | 2020-03-12 |
AU2018270926A1 (en) | 2019-11-07 |
EP3624827A1 (en) | 2020-03-25 |
AU2022203691B2 (en) | 2023-10-12 |
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