JP7315564B2 - グリカン分析のためのブロックされた２－ａａを使用するための方法およびキット - Google Patents

グリカン分析のためのブロックされた２－ａａを使用するための方法およびキット Download PDF

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JP7315564B2
JP7315564B2 JP2020541778A JP2020541778A JP7315564B2 JP 7315564 B2 JP7315564 B2 JP 7315564B2 JP 2020541778 A JP2020541778 A JP 2020541778A JP 2020541778 A JP2020541778 A JP 2020541778A JP 7315564 B2 JP7315564 B2 JP 7315564B2
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acid
boc
kit
glycans
organic solvent
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JP2021513059A (ja
JP2021513059A5 (https=
Inventor
ブラセンコ，セルゲイ
アクソー，フランシス・ティー
ナヴァロ，アンドレス ゲレーロ
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Agilent Technologies Inc
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Agilent Technologies Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/04—Monocyclic monocarboxylic acids
    • C07C63/06—Benzoic acid
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2020541778A 2018-02-02 2019-01-31 グリカン分析のためのブロックされた２－ａａを使用するための方法およびキット Active JP7315564B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862625846P 2018-02-02 2018-02-02
US62/625,846 2018-02-02
PCT/US2019/016169 WO2019152724A1 (en) 2018-02-02 2019-01-31 Methods and kits for using blocked 2-aa for glycan analysis

Publications (3)

Publication Number Publication Date
JP2021513059A JP2021513059A (ja) 2021-05-20
JP2021513059A5 JP2021513059A5 (https=) 2022-02-08
JP7315564B2 true JP7315564B2 (ja) 2023-07-26

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JP2020541778A Active JP7315564B2 (ja) 2018-02-02 2019-01-31 グリカン分析のためのブロックされた２－ａａを使用するための方法およびキット

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Country Link
US (1) US11376200B2 (https=)
JP (1) JP7315564B2 (https=)
CN (1) CN111867549B (https=)
WO (1) WO2019152724A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12180581B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US12181452B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
US12352734B2 (en) 2020-09-24 2025-07-08 Waters Technologies Corporation Chromatographic hardware improvements for separation of reactive molecules

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040248890A1 (en) 2003-03-03 2004-12-09 Gonzalez Jesus E. Quinazolines useful as modulators of ion channels
US20080207487A1 (en) 2006-11-02 2008-08-28 Neose Technologies, Inc. Manufacturing process for the production of polypeptides expressed in insect cell-lines
US20090088454A1 (en) 1999-06-25 2009-04-02 The Regents Of The University Of Colorado Anti-cancer compounds
JP2012162516A (ja) 2010-11-19 2012-08-30 Mitsubishi Chemicals Corp ４−アルキニル−１，３−ジオキソラン−２−オン誘導体の製造法
JP2013506115A (ja) 2009-09-29 2013-02-21 レイデン ユニバーシティ メディカル センター 還元剤として２−ピコリンボランを使用する炭水化物の還元的アミノ化及び分析
JP2013525437A (ja) 2010-04-30 2013-06-20 プロステッタ アンチバイラル インコーポレイテッド 抗ウイルス化合物
JP2017524128A (ja) 2014-07-18 2017-08-24 ヘキサル・アクチェンゲゼルシャフト 血清試料中の糖タンパク質のグリカンをマッピングするための改善された方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1130399B1 (en) * 1992-05-29 2009-04-01 The Rockefeller University Method for the sequence determination of peptides using a mass spectrometer
GB9310467D0 (en) * 1993-05-20 1993-07-07 Oxford Glycosystems Ltd Glycoconjugates
US5977074A (en) * 1993-10-01 1999-11-02 Merrell Pharmaceuticals, Inc. Inhibitors of β-amyloid protein production
NZ274074A (en) * 1993-10-01 1997-11-24 Merrell Pharma Inc Various dipeptide derivatives having a reduced carboxy group, the aldehyde being optionally substituted; pharmaceutical compositions
US8524784B2 (en) * 2009-04-30 2013-09-03 Intezyne Technologies, Incorporated Polymer micelles containing anthracylines for the treatment of cancer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088454A1 (en) 1999-06-25 2009-04-02 The Regents Of The University Of Colorado Anti-cancer compounds
US20040248890A1 (en) 2003-03-03 2004-12-09 Gonzalez Jesus E. Quinazolines useful as modulators of ion channels
US20080207487A1 (en) 2006-11-02 2008-08-28 Neose Technologies, Inc. Manufacturing process for the production of polypeptides expressed in insect cell-lines
JP2013506115A (ja) 2009-09-29 2013-02-21 レイデン ユニバーシティ メディカル センター 還元剤として２−ピコリンボランを使用する炭水化物の還元的アミノ化及び分析
JP2013525437A (ja) 2010-04-30 2013-06-20 プロステッタ アンチバイラル インコーポレイテッド 抗ウイルス化合物
JP2012162516A (ja) 2010-11-19 2012-08-30 Mitsubishi Chemicals Corp ４−アルキニル−１，３−ジオキソラン−２−オン誘導体の製造法
JP2017524128A (ja) 2014-07-18 2017-08-24 ヘキサル・アクチェンゲゼルシャフト 血清試料中の糖タンパク質のグリカンをマッピングするための改善された方法

Also Published As

Publication number Publication date
JP2021513059A (ja) 2021-05-20
CN111867549A (zh) 2020-10-30
US11376200B2 (en) 2022-07-05
CN111867549B (zh) 2024-01-05
US20210045981A1 (en) 2021-02-18
WO2019152724A1 (en) 2019-08-08

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