JP7284877B2 - ロピニロール含有貼付剤及びロピニロールの皮膚透過性向上方法 - Google Patents

ロピニロール含有貼付剤及びロピニロールの皮膚透過性向上方法 Download PDF

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Publication number
JP7284877B2
JP7284877B2 JP2022559066A JP2022559066A JP7284877B2 JP 7284877 B2 JP7284877 B2 JP 7284877B2 JP 2022559066 A JP2022559066 A JP 2022559066A JP 2022559066 A JP2022559066 A JP 2022559066A JP 7284877 B2 JP7284877 B2 JP 7284877B2
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Prior art keywords
ropinirole
adhesive layer
group
sodium
pharmaceutically acceptable
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Japanese (ja)
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JPWO2022091925A1 (https=
Inventor
尚志 内田
智史 天野
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Hisamitsu Pharmaceutical Co Inc
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Hisamitsu Pharmaceutical Co Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022559066A 2020-10-29 2021-10-21 ロピニロール含有貼付剤及びロピニロールの皮膚透過性向上方法 Active JP7284877B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020181280 2020-10-29
JP2020181280 2020-10-29
PCT/JP2021/038892 WO2022091925A1 (ja) 2020-10-29 2021-10-21 ロピニロール含有貼付剤及びロピニロールの皮膚透過性向上方法

Publications (2)

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JPWO2022091925A1 JPWO2022091925A1 (https=) 2022-05-05
JP7284877B2 true JP7284877B2 (ja) 2023-05-31

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JP2022559066A Active JP7284877B2 (ja) 2020-10-29 2021-10-21 ロピニロール含有貼付剤及びロピニロールの皮膚透過性向上方法

Country Status (8)

Country Link
US (1) US12440452B2 (https=)
EP (1) EP4238563B1 (https=)
JP (1) JP7284877B2 (https=)
KR (1) KR102577838B1 (https=)
CN (1) CN116322658B (https=)
ES (1) ES3049508T3 (https=)
TW (1) TWI821765B (https=)
WO (1) WO2022091925A1 (https=)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009107478A1 (ja) 2008-02-27 2009-09-03 久光製薬株式会社 貼付剤及び包装体
JP2012140407A (ja) 2010-12-13 2012-07-26 Hisamitsu Pharmaceut Co Inc 経皮吸収促進剤、ならびにそれを含有する医薬組成物および貼付剤
JP2015526480A (ja) 2012-08-24 2015-09-10 インテグアールエックス セラピューティクス， エルエルシーＩｎｔｅｇｕｒｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｌｌｃ 治療剤の経皮送達を増強するための化学組成物および方法
JP2016535781A (ja) 2013-11-03 2016-11-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 経皮薬物送達のためのイオン性液体
JP2017178967A (ja) 2015-08-29 2017-10-05 株式会社 メドレックス 酸捕捉剤を含有する貼付製剤

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5872111A (en) * 1997-05-19 1999-02-16 Lever Brothers Company, Division Of Conopco, Inc. Compositions comprising glycosylamide surfactants
DE10137162A1 (de) * 2001-07-30 2003-02-20 Hexal Ag Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol
EP2258369B1 (en) 2008-02-27 2015-04-08 Hisamitsu Pharmaceutical Co., Inc. Medicated patch
ES2513691T3 (es) 2009-05-21 2014-10-27 Hisamitsu Pharmaceutical Co., Inc. Preparación transdérmica
WO2012165253A1 (ja) 2011-05-31 2012-12-06 久光製薬株式会社 ロピニロール含有貼付剤及びその包装体
KR101848961B1 (ko) 2011-05-31 2018-04-13 히사미쓰 세이야꾸 가부시키가이샤 로피니롤 함유 첩부제 및 그 포장체
EP2786752B1 (en) * 2011-12-01 2019-06-12 Teikoku Seiyaku Co., Ltd. Ropinirole-containing adhesive patch
CA2924233C (en) * 2013-10-07 2018-10-23 Teikoku Pharma Usa, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
JP6373061B2 (ja) * 2014-05-23 2018-08-15 帝國製薬株式会社 経皮投与製剤
MX389514B (es) * 2015-10-01 2025-03-20 Firmenich Incorporated Compuestos útiles como moduladores de canal receptor 8 de potencial transitorio de melastatina (trpm8).
EP3586841B1 (en) * 2017-02-24 2023-12-27 Hisamitsu Pharmaceutical Co., Inc. Adhesive skin patch and packaged product thereof
TWI825013B (zh) * 2017-04-19 2023-12-11 日商帝國製藥股份有限公司 含有盧帕他定（ｒｕｐａｔａｄｉｎｅ）之貼附劑
CN107375249A (zh) * 2017-07-26 2017-11-24 徐静 一种含罗匹尼罗的缓释透皮贴剂及其应用
US20200297654A1 (en) * 2017-10-17 2020-09-24 Lubrizol Advanced Materials, Inc. Composition and device for delivery of active agents to skin surfaces

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009107478A1 (ja) 2008-02-27 2009-09-03 久光製薬株式会社 貼付剤及び包装体
JP2012140407A (ja) 2010-12-13 2012-07-26 Hisamitsu Pharmaceut Co Inc 経皮吸収促進剤、ならびにそれを含有する医薬組成物および貼付剤
JP2015526480A (ja) 2012-08-24 2015-09-10 インテグアールエックス セラピューティクス， エルエルシーＩｎｔｅｇｕｒｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｌｌｃ 治療剤の経皮送達を増強するための化学組成物および方法
JP2016535781A (ja) 2013-11-03 2016-11-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 経皮薬物送達のためのイオン性液体
JP2017178967A (ja) 2015-08-29 2017-10-05 株式会社 メドレックス 酸捕捉剤を含有する貼付製剤

Also Published As

Publication number Publication date
EP4238563A4 (en) 2024-10-02
TW202227052A (zh) 2022-07-16
JPWO2022091925A1 (https=) 2022-05-05
ES3049508T3 (en) 2025-12-17
CN116322658A (zh) 2023-06-23
CN116322658B (zh) 2025-09-26
WO2022091925A1 (ja) 2022-05-05
EP4238563A1 (en) 2023-09-06
EP4238563B1 (en) 2025-09-24
KR102577838B1 (ko) 2023-09-12
US20240016758A1 (en) 2024-01-18
TWI821765B (zh) 2023-11-11
KR20230088789A (ko) 2023-06-20
US12440452B2 (en) 2025-10-14

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