JP7270254B2 - 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク - Google Patents

改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク Download PDF

Info

Publication number
JP7270254B2
JP7270254B2 JP2019568598A JP2019568598A JP7270254B2 JP 7270254 B2 JP7270254 B2 JP 7270254B2 JP 2019568598 A JP2019568598 A JP 2019568598A JP 2019568598 A JP2019568598 A JP 2019568598A JP 7270254 B2 JP7270254 B2 JP 7270254B2
Authority
JP
Japan
Prior art keywords
resonator
resonators
input
output
label
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019568598A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020523587A5 (enExample
JP2020523587A (ja
Inventor
アルビン アール． レベック，
クリス ドワイヤー，
クレイグ ラボダ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of JP2020523587A publication Critical patent/JP2020523587A/ja
Publication of JP2020523587A5 publication Critical patent/JP2020523587A5/ja
Priority to JP2023026034A priority Critical patent/JP7601432B2/ja
Application granted granted Critical
Publication of JP7270254B2 publication Critical patent/JP7270254B2/ja
Priority to JP2024186553A priority patent/JP2025010178A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432—Quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2019568598A 2017-06-16 2018-06-12 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク Active JP7270254B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023026034A JP7601432B2 (ja) 2017-06-16 2023-02-22 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2024186553A JP2025010178A (ja) 2017-06-16 2024-10-23 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762521192P 2017-06-16 2017-06-16
US62/521,192 2017-06-16
US201762527451P 2017-06-30 2017-06-30
US62/527,451 2017-06-30
US201762551616P 2017-08-29 2017-08-29
US62/551,616 2017-08-29
PCT/US2018/037076 WO2018231805A2 (en) 2017-06-16 2018-06-12 Resonator networks for improved label detection, computation, analyte sensing, and tunable random number generation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023026034A Division JP7601432B2 (ja) 2017-06-16 2023-02-22 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク

Publications (3)

Publication Number Publication Date
JP2020523587A JP2020523587A (ja) 2020-08-06
JP2020523587A5 JP2020523587A5 (enExample) 2021-07-26
JP7270254B2 true JP7270254B2 (ja) 2023-05-10

Family

ID=64659322

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019568598A Active JP7270254B2 (ja) 2017-06-16 2018-06-12 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2023026034A Active JP7601432B2 (ja) 2017-06-16 2023-02-22 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2024186553A Pending JP2025010178A (ja) 2017-06-16 2024-10-23 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023026034A Active JP7601432B2 (ja) 2017-06-16 2023-02-22 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
JP2024186553A Pending JP2025010178A (ja) 2017-06-16 2024-10-23 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク

Country Status (10)

Country Link
US (3) US11674901B2 (enExample)
EP (2) EP4075133A3 (enExample)
JP (3) JP7270254B2 (enExample)
KR (2) KR102795781B1 (enExample)
CN (2) CN111148987B (enExample)
AU (1) AU2018282868B2 (enExample)
CA (1) CA3067362C (enExample)
IL (1) IL271386B2 (enExample)
SG (1) SG11201912217WA (enExample)
WO (1) WO2018231805A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019191482A1 (en) 2018-03-30 2019-10-03 Becton, Dickinson And Company Water-soluble polymeric dyes having pendant chromophores
JP7505698B2 (ja) * 2019-03-20 2024-06-25 国立大学法人大阪大学 信号処理装置及び信号処理方法
CN114555125A (zh) * 2019-10-25 2022-05-27 菲托尼尔斯股份有限公司 多核苷酸连接的生物缀合物及其制备和使用方法
CN114441752B (zh) * 2020-11-03 2024-11-26 中国科学院苏州纳米技术与纳米仿生研究所 一种筛选方法
US20240175072A1 (en) 2020-12-10 2024-05-30 Thermo Fisher Scientific Inc. Method And Composition For Multiplexed And Multimodal Single Cell Analysis
WO2022125744A2 (en) 2020-12-10 2022-06-16 Phitonex, Inc. Methods of signal amplification -
US12180401B2 (en) 2021-04-07 2024-12-31 Becton, Dickinson And Company Water-soluble fluorescent polymeric dyes
WO2024157278A1 (en) 2023-01-27 2024-08-02 Invitrogen Bioservices India Private Limited Rapid expression and screening of cell penetrating peptides
WO2025090132A2 (en) 2023-05-12 2025-05-01 Life Technolohgies Corporation Methods and kits for detecting endotoxin

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160411A1 (en) 1999-12-14 2002-10-31 Research Corporation Technologies, Inc. Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same
JP2012515905A (ja) 2009-01-22 2012-07-12 ウニベルジテート ポツダム 多重化ｆｒｅｔ解析により試料中の検体を検出する方法及びキット
US20130309671A1 (en) 2012-05-18 2013-11-21 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Spectro-Temporal Optical Encoding of Information Using a Time-Gated Fluorescence Resonance Energy Transfer (FRET)
US20150293022A1 (en) 2014-04-15 2015-10-15 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Use of Modular Nucleic Acid Scaffolds to Create Nanoscale Energy Harvesting and Focusing Arrays
JP2016014033A (ja) 2009-02-18 2016-01-28 カーネギー メロン ユニバーシティ 明検出のためのクエンチャー付加デンドリマー色素

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565322A (en) * 1991-11-07 1996-10-15 Nanogen, Inc. Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to donor energy transfer system
US7348181B2 (en) * 1997-10-06 2008-03-25 Trustees Of Tufts College Self-encoding sensor with microspheres
US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
WO2002040701A2 (en) 2000-11-08 2002-05-23 The Scripps Research Institute Energy transfer labels with mechanically linked fluorophores
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
ATE476521T1 (de) 2002-06-20 2010-08-15 Univ California Verfahren und zusammensetzungen zum nachweis und zur analyse von polynukleotiden unter verwendung von licht einfangenden multichromophoren
WO2004092324A2 (en) * 2002-08-26 2004-10-28 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
EP2351856A1 (en) 2003-02-13 2011-08-03 The Regents Of the University of California Methods and compositions for detection and analysis of polynucleotide-binding protein interactions using light harvesting multichromophores
US7754832B2 (en) 2003-02-28 2010-07-13 The Regents Of The University Of California Block copolyolefins possessing a tapered structure
US7825200B2 (en) 2003-02-28 2010-11-02 The Regents Of The University Of California Controlled free radical grafting from polyolefins
JP2007502992A (ja) 2003-08-20 2007-02-15 ビージー メディシン， インコーポレイテッド 生物システムのプロファイリングのための方法およびシステム
DE112004001737B4 (de) 2003-09-17 2016-08-11 The Regents Of The University Of California Verfahren umfassend lösliche, konjugierte Polymere zur Ausbildung benachbarter Schichten auf einem Substrat oder zum Hinzufügen einer Polymerschicht zu einem Substrat, mehrschichtige elektronische Vorrichtung und Verwendung in elektronischen Bauteilen
US7830085B2 (en) 2003-10-06 2010-11-09 The Regents Of The University Of California White electrophosphorescence from semiconducting polymer blends
KR20070018083A (ko) * 2004-05-27 2007-02-13 쓰리엠 이노베이티브 프로퍼티즈 컴파니 광대역 광원으로 여기된 유전체 미세공동 형광 센서
US7271379B2 (en) * 2004-05-27 2007-09-18 3M Innovative Properties Company Dielectric microcavity fluorosensors excited with a broadband light source
US20060021673A1 (en) 2004-07-27 2006-02-02 Stephan Rodewald Self-sealing apparatus for chemical reaction vessel
DE112005002132T5 (de) 2004-09-03 2008-03-06 The Regents Of The University Of California, Oakland Lösliche konjugierte Polymere
US8795781B2 (en) 2004-09-03 2014-08-05 The Regents Of The University Of California Methods and devices utilizing soluble conjugated polymers
EP2502946B1 (en) 2005-01-10 2017-10-04 The Regents of The University of California Cationic conjugated polymers suitable for strand-specific polynucleiotide detection in homogeneous and solid state assays
US8076842B2 (en) 2005-03-01 2011-12-13 The Regents Of The University Of California Multilayer polymer light-emitting diodes for solid state lighting applications
EP1929300B1 (en) 2005-08-30 2017-12-13 Agency for Science, Technology and Research Water-soluble fluorescent particle comprising entangled fluorescent polymer and amphiphilic molecule
US20070275388A1 (en) 2006-05-25 2007-11-29 Daniel Ryan Dendrimers that possess a single target annealing site and uses thereof
JP5088034B2 (ja) 2006-08-14 2012-12-05 ソニー株式会社 物質の検出等に有用な核酸鎖とその方法
CN101553579B (zh) 2006-10-06 2016-01-20 赛里根有限公司 用于定向生物标志物信号放大的荧光方法和材料
US7796262B1 (en) * 2007-05-31 2010-09-14 Nomadics, Inc. Integrated optical resonator device for measuring chemical and biological analyte concentrations
US20090325211A1 (en) * 2007-10-06 2009-12-31 Ye Fang System and method for dual-detection of a cellular response
US8309306B2 (en) 2008-11-12 2012-11-13 Nodality, Inc. Detection composition
US8218151B2 (en) 2009-03-12 2012-07-10 Tel Aviv University Future Technology Development Ltd Light-emitting intra-cavity interferometric sensors
US8969509B2 (en) 2009-06-26 2015-03-03 Sirigen, Inc. Signal amplified biological detection with conjugated polymers
JP2013506418A (ja) 2009-09-30 2013-02-28 クアンタポール， インコーポレイテッド 標識されたナノポアを使用する生物学的なポリマーの超高速配列決定
ES2974909T3 (es) 2010-01-19 2024-07-02 Sirigen Ii Ltd Nuevos reactivos para la amplificación dirigida de la señal de un biomarcador
EP3266881B1 (en) * 2010-11-05 2019-12-25 Genalyte, Inc. Optical analyte detection systems and methods of use
ES2829973T3 (es) 2010-11-22 2021-06-02 Univ California Cromóforos semiconductores de moléculas pequeñas orgánicas para su uso en dispositivos electrónicos orgánicos
CN102590160A (zh) 2011-01-13 2012-07-18 索尼公司 荧光量子点/纳米金属颗粒偶联物及其制备和应用
EP2721087B1 (en) 2011-06-17 2018-03-07 The Regents of The University of California Regioregular pyridal[2,1,3]thiadiazole pi-conjugated copolymers for organic semiconductors
US20130032791A1 (en) 2011-06-24 2013-02-07 Bazan Guillermo C Conjugated polymers having an imine group at the intrachain electron donor bridgehead position useful in electronic devices
US20160150963A1 (en) * 2011-09-26 2016-06-02 Michael Lee Roukes One-photon integrated neurophotonic systems
US20130247989A1 (en) 2012-03-23 2013-09-26 The Regents Of The University Of California Inert solution-processable molecular chromophores for organic electronic devices
US8729221B2 (en) 2012-04-25 2014-05-20 The Regents Of The University Of California Conjugated copolymers chiral side chain for organic thin film transistors
EP3019559A4 (en) 2013-08-22 2017-04-05 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
MX392471B (es) * 2013-11-17 2025-03-24 Quantum Si Inc Sistema optico y chip de ensayo para sondear, detectar y analizar moleculas
KR101829159B1 (ko) 2014-01-16 2018-02-13 소니 주식회사 수용성 형광 또는 유색 염료
EP2940150A1 (en) * 2014-04-29 2015-11-04 Baseclick GmbH Self-assembly of DNA Origami: a new diganostic tool
EP3143165A4 (en) 2014-05-15 2018-05-16 Two Pore Guys, Inc. Scaffold data storage and target detection in a sample using a nanopore
KR102472061B1 (ko) * 2014-08-08 2022-11-29 퀀텀-에스아이 인코포레이티드 분자들을 프로빙, 검출 및 분석하기 위한 광학계 및 검정 칩
EP3191840B1 (en) * 2014-09-12 2020-04-08 Purdue Research Foundation Metal-antibody tagging and plasma-based detection
KR102676814B1 (ko) 2015-02-26 2024-06-21 소니그룹주식회사 접합 그룹을 포함하는 수용성 형광 또는 착색 염료
JP6849599B2 (ja) 2015-05-11 2021-03-24 ソニー株式会社 超明色ダイマーまたはポリマー染料
US10487173B2 (en) 2015-11-11 2019-11-26 The Regents Of The University Of California Fluorine substitution influence on benzo[2,1,3]thiodiazole based polymers for field-effect transistor applications
EP3416691A4 (en) 2016-02-19 2020-02-26 Genisphere, LLC SUPPORTS OF NUCLEIC ACIDS AND THEIR THERAPEUTIC METHODS OF USE
US10465233B2 (en) * 2016-03-25 2019-11-05 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Time-resolved nucleic acid hybridization beacons
KR102530707B1 (ko) 2016-04-01 2023-05-11 소니그룹주식회사 초휘도 이량체성 또는 중합체성 염료
US11434377B2 (en) 2016-04-01 2022-09-06 Sony Corporation Ultra bright dimeric or polymeric dyes with rigid spacing groups
KR20180133890A (ko) 2016-04-06 2018-12-17 소니 주식회사 스페이싱 링커 그룹을 포함하는 초고명도 이량체성 또는 중합체성 염료
US20170309825A1 (en) 2016-04-25 2017-10-26 The Regents Of The University Of California Novel weak donor-acceptor conjugated copolymers for field- effect transistor applications
WO2017196954A1 (en) 2016-05-10 2017-11-16 Sony Corporation Ultra bright polymeric dyes with peptide backbones
WO2017197014A2 (en) 2016-05-10 2017-11-16 Sony Corporation Compositions comprising a polymeric dye and a cyclodextrin and uses thereof
EP3455300A1 (en) 2016-05-11 2019-03-20 Sony Corporation Ultra bright dimeric or polymeric dyes
JP7068191B2 (ja) 2016-06-06 2022-05-16 ソニーグループ株式会社 蛍光または有色レポーター基を含むイオン性ポリマー
US12018159B2 (en) 2016-07-29 2024-06-25 Sony Group Corporation Ultra bright dimeric or polymeric dyes and methods for preparation of the same
US11193057B2 (en) 2016-08-29 2021-12-07 Life Technologies Corporation Fluorescent particles
US20180092993A1 (en) 2016-09-01 2018-04-05 Life Technologies Corporation Compositions and methods for enhanced fluorescence
IL250207A0 (en) 2017-01-19 2017-03-30 Augmanity Nano Ltd Origami RNA from ribosomal RNA and methods for its preparation
KR102742386B1 (ko) 2018-03-19 2024-12-16 소니그룹주식회사 형광 신호 향상을 위한 2가 금속의 사용
WO2019182766A1 (en) 2018-03-21 2019-09-26 Sony Corporation Polymeric tandem dyes with linker groups
KR102854332B1 (ko) 2018-06-27 2025-09-03 소니그룹주식회사 디옥시리보오스를 포함하는 링커 군을 갖는 중합체성 염료
WO2020014634A1 (en) 2018-07-13 2020-01-16 Sony Corporation Polymeric dyes having a backbone comprising organophosphate units

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020160411A1 (en) 1999-12-14 2002-10-31 Research Corporation Technologies, Inc. Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same
JP2012515905A (ja) 2009-01-22 2012-07-12 ウニベルジテート ポツダム 多重化ｆｒｅｔ解析により試料中の検体を検出する方法及びキット
JP2016014033A (ja) 2009-02-18 2016-01-28 カーネギー メロン ユニバーシティ 明検出のためのクエンチャー付加デンドリマー色素
US20130309671A1 (en) 2012-05-18 2013-11-21 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Spectro-Temporal Optical Encoding of Information Using a Time-Gated Fluorescence Resonance Energy Transfer (FRET)
US20150293022A1 (en) 2014-04-15 2015-10-15 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Use of Modular Nucleic Acid Scaffolds to Create Nanoscale Energy Harvesting and Focusing Arrays

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Buckhout-White, S. et al.，Assembling programmable FRET-based photonic networks using designer DNA scaffolds，Nat. Commun.，2014年12月11日，Vol. 5, Article No. 5615，pp. 1-16，doi:10.1038/ncomms6615
DIAZ, S. A. et al.，Extending DNA-Based Molecular Photonic Wires with Homogeneous Forster Resonance Energy Transfer，Adv. Optical Mater.，2016年01月07日，Vol. 4，pp. 399-412，doi:10.1002/adom.201500554
Dwyer, C. et al.，DNA Self-Assembled Nanostructures for Resonance Energy Transfer Circuits，Nanophotonic Information Physics，2013年12月08日，pp. 41-65，doi:10.1007/978-3-642-40224-1_2
LaBoda C. et al.，DNA-Enabled Integrated Molecular Systems for Computation and Sensing，Acc. Chem. Res.，2014年05月21日，Vol. 47，pp. 1816-1824，doi:10.1021/ar5000054u
Olejko L. and Bald I.，FRET efficiency and antenna effect in multi-color DNA origami-based light harvesting systems，RSC Advances，2017年05月03日，Vol. 7，pp. 23924-23934，doi:10.1039/c7ra02114c

Also Published As

Publication number Publication date
IL271386B1 (en) 2024-10-01
AU2018282868A1 (en) 2020-01-02
KR20230147735A (ko) 2023-10-23
KR102584549B1 (ko) 2023-10-05
AU2018282868B2 (en) 2023-10-19
WO2018231805A3 (en) 2019-02-21
CN111148987B (zh) 2023-04-14
CN116519642A (zh) 2023-08-01
KR20200016376A (ko) 2020-02-14
CA3067362A1 (en) 2018-12-20
IL271386A (en) 2020-01-30
US20200124532A1 (en) 2020-04-23
US20210396676A1 (en) 2021-12-23
SG11201912217WA (en) 2020-01-30
US11674901B2 (en) 2023-06-13
EP4075133A3 (en) 2022-11-23
US11959855B2 (en) 2024-04-16
US20210325304A1 (en) 2021-10-21
CN111148987A (zh) 2020-05-12
EP3639013A2 (en) 2020-04-22
CA3067362C (en) 2024-10-29
JP2023057173A (ja) 2023-04-20
WO2018231805A2 (en) 2018-12-20
EP4075133A2 (en) 2022-10-19
JP7601432B2 (ja) 2024-12-17
JP2025010178A (ja) 2025-01-20
US11959854B2 (en) 2024-04-16
KR102795781B1 (ko) 2025-04-15
IL271386B2 (en) 2025-02-01
JP2020523587A (ja) 2020-08-06
EP3639013A4 (en) 2021-06-30

Similar Documents

Publication Publication Date Title
JP7270254B2 (ja) 改善された標識検出、演算、検体感知、および調整可能な乱数生成のための共鳴体ネットワーク
Petryayeva et al. Quantum dots in bioanalysis: a review of applications across various platforms for fluorescence spectroscopy and imaging
US8921277B2 (en) Multiplexed flow assay based on absorption-encoded micro beads
Ishikawa-Ankerhold et al. Advanced fluorescence microscopy techniques—Frap, Flip, Flap, Fret and flim
US7332344B2 (en) Luminescence assays
Goryacheva et al. Lanthanide-to-quantum dot Förster resonance energy transfer (FRET): Application for immunoassay
US7076092B2 (en) High-throughput, dual probe biological assays based on single molecule detection
Swift et al. A two-photon excitation fluorescence cross-correlation assay for a model ligand-receptor binding system using quantum dots
Gerber et al. Tailoring light emission properties of fluorophores by coupling to resonance-tuned metallic nanostructures
CN104115001B (zh) 利用单个粒子检测的光分析装置、光分析方法
JP2020523587A5 (enExample)
Hedley et al. Picosecond time-resolved photon antibunching measures nanoscale exciton motion and the true number of chromophores
Szalkowski et al. Advances in the photon avalanche luminescence of inorganic lanthanide-doped nanomaterials
JP2005502880A (ja) 発光に基づくセンサーアセンブリー
JP6010029B2 (ja) 蛍光粒子の検出方法
Herman et al. Measurement of fluorescence resonance energy transfer in the optical microscope
Mahe You are currently viewing the US site-Switch to UK site
US8039818B2 (en) Sub wavelength aperture
Hohlbein Single molecule fluorescence detection in nanoscale confinement
Wei et al. Forster Resonance Energy Transfer in a Hybrid System of CdTe Quantum dots-RhB
HERMAN et al. Resonance Energy Transfer in the Optical Microscope
WO2016009352A1 (es) Método de sensado molecular basado en modulación de luminiscencia por calentamiento específico de nanopartículas

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210604

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210604

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20220218

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220324

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220624

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20221025

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230222

C60 Trial request (containing other claim documents, opposition documents)

Free format text: JAPANESE INTERMEDIATE CODE: C60

Effective date: 20230222

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20230302

C21 Notice of transfer of a case for reconsideration by examiners before appeal proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C21

Effective date: 20230303

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230403

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230418

R150 Certificate of patent or registration of utility model

Ref document number: 7270254

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150