IL271386B2 - Enhanced resonator networks for label detection, computation, analyte sensing, and tunable random number generation - Google Patents
Enhanced resonator networks for label detection, computation, analyte sensing, and tunable random number generationInfo
- Publication number
- IL271386B2 IL271386B2 IL271386A IL27138619A IL271386B2 IL 271386 B2 IL271386 B2 IL 271386B2 IL 271386 A IL271386 A IL 271386A IL 27138619 A IL27138619 A IL 27138619A IL 271386 B2 IL271386 B2 IL 271386B2
- Authority
- IL
- Israel
- Prior art keywords
- resonator
- resonators
- input
- label
- output
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6432—Quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762521192P | 2017-06-16 | 2017-06-16 | |
| US201762527451P | 2017-06-30 | 2017-06-30 | |
| US201762551616P | 2017-08-29 | 2017-08-29 | |
| PCT/US2018/037076 WO2018231805A2 (en) | 2017-06-16 | 2018-06-12 | Resonator networks for improved label detection, computation, analyte sensing, and tunable random number generation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL271386A IL271386A (en) | 2020-01-30 |
| IL271386B1 IL271386B1 (en) | 2024-10-01 |
| IL271386B2 true IL271386B2 (en) | 2025-02-01 |
Family
ID=64659322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL271386A IL271386B2 (en) | 2017-06-16 | 2018-06-12 | Enhanced resonator networks for label detection, computation, analyte sensing, and tunable random number generation |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11674901B2 (enExample) |
| EP (2) | EP4075133A3 (enExample) |
| JP (3) | JP7270254B2 (enExample) |
| KR (2) | KR102795781B1 (enExample) |
| CN (2) | CN111148987B (enExample) |
| AU (1) | AU2018282868B2 (enExample) |
| CA (1) | CA3067362C (enExample) |
| IL (1) | IL271386B2 (enExample) |
| SG (1) | SG11201912217WA (enExample) |
| WO (1) | WO2018231805A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019191482A1 (en) | 2018-03-30 | 2019-10-03 | Becton, Dickinson And Company | Water-soluble polymeric dyes having pendant chromophores |
| JP7505698B2 (ja) * | 2019-03-20 | 2024-06-25 | 国立大学法人大阪大学 | 信号処理装置及び信号処理方法 |
| CN114555125A (zh) * | 2019-10-25 | 2022-05-27 | 菲托尼尔斯股份有限公司 | 多核苷酸连接的生物缀合物及其制备和使用方法 |
| CN114441752B (zh) * | 2020-11-03 | 2024-11-26 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种筛选方法 |
| US20240175072A1 (en) | 2020-12-10 | 2024-05-30 | Thermo Fisher Scientific Inc. | Method And Composition For Multiplexed And Multimodal Single Cell Analysis |
| WO2022125744A2 (en) | 2020-12-10 | 2022-06-16 | Phitonex, Inc. | Methods of signal amplification - |
| US12180401B2 (en) | 2021-04-07 | 2024-12-31 | Becton, Dickinson And Company | Water-soluble fluorescent polymeric dyes |
| WO2024157278A1 (en) | 2023-01-27 | 2024-08-02 | Invitrogen Bioservices India Private Limited | Rapid expression and screening of cell penetrating peptides |
| WO2025090132A2 (en) | 2023-05-12 | 2025-05-01 | Life Technolohgies Corporation | Methods and kits for detecting endotoxin |
Citations (1)
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2018
- 2018-06-12 AU AU2018282868A patent/AU2018282868B2/en active Active
- 2018-06-12 SG SG11201912217WA patent/SG11201912217WA/en unknown
- 2018-06-12 US US16/605,555 patent/US11674901B2/en active Active
- 2018-06-12 JP JP2019568598A patent/JP7270254B2/ja active Active
- 2018-06-12 KR KR1020237032999A patent/KR102795781B1/ko active Active
- 2018-06-12 CN CN201880047719.7A patent/CN111148987B/zh active Active
- 2018-06-12 KR KR1020207000996A patent/KR102584549B1/ko active Active
- 2018-06-12 CN CN202310427962.4A patent/CN116519642A/zh active Pending
- 2018-06-12 WO PCT/US2018/037076 patent/WO2018231805A2/en not_active Ceased
- 2018-06-12 EP EP22160767.4A patent/EP4075133A3/en active Pending
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| AU2018282868A1 (en) | 2020-01-02 |
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| AU2018282868B2 (en) | 2023-10-19 |
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| CA3067362C (en) | 2024-10-29 |
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| JP7601432B2 (ja) | 2024-12-17 |
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| KR102795781B1 (ko) | 2025-04-15 |
| JP2020523587A (ja) | 2020-08-06 |
| EP3639013A4 (en) | 2021-06-30 |
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