JP7267675B2 - ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 - Google Patents

６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 Download PDF

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JP7267675B2
JP7267675B2 JP2017551949A JP2017551949A JP7267675B2 JP 7267675 B2 JP7267675 B2 JP 7267675B2 JP 2017551949 A JP2017551949 A JP 2017551949A JP 2017551949 A JP2017551949 A JP 2017551949A JP 7267675 B2 JP7267675 B2 JP 7267675B2
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sodium salt
crystals
hydrate
aqueous solution
crystal
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JPWO2017086443A1 (ja
Inventor
将大 阿部
友哉 横井
崇太郎 三平
一成 福本
宏 長野
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Kyowa Hakko Bio Co Ltd
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Kyowa Hakko Bio Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2017551949A 2015-11-18 2016-11-18 ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法 Active JP7267675B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015225652 2015-11-18
JP2015225652 2015-11-18
PCT/JP2016/084282 WO2017086443A1 (ja) 2015-11-18 2016-11-18 ６'－シアリルラクトースナトリウム塩の結晶およびその製造方法

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JP2020201994A Division JP2021036002A (ja) 2015-11-18 2020-12-04 ６’−シアリルラクトースナトリウム塩の結晶およびその製造方法

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JPWO2017086443A1 JPWO2017086443A1 (ja) 2018-08-30
JP7267675B2 true JP7267675B2 (ja) 2023-05-02

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JP2017551949A Active JP7267675B2 (ja) 2015-11-18 2016-11-18 ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法
JP2020201994A Withdrawn JP2021036002A (ja) 2015-11-18 2020-12-04 ６’−シアリルラクトースナトリウム塩の結晶およびその製造方法
JP2022038512A Withdrawn JP2022069548A (ja) 2015-11-18 2022-03-11 ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法

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JP2020201994A Withdrawn JP2021036002A (ja) 2015-11-18 2020-12-04 ６’−シアリルラクトースナトリウム塩の結晶およびその製造方法
JP2022038512A Withdrawn JP2022069548A (ja) 2015-11-18 2022-03-11 ６’－シアリルラクトースナトリウム塩の結晶およびその製造方法

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US (1) US10745432B2 (https=)
EP (1) EP3378868A4 (https=)
JP (3) JP7267675B2 (https=)
WO (1) WO2017086443A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017195743A1 (ja) * 2016-05-09 2017-11-16 協和発酵バイオ株式会社 ３'－シアリルラクトースナトリウム塩・ｎ水和物の結晶及びその製造方法
WO2018225790A1 (ja) * 2017-06-08 2018-12-13 協和発酵バイオ株式会社 酸化型グルタチオン・二カチオン塩の結晶及びその製造方法
US11214588B2 (en) 2017-06-30 2022-01-04 Glycom A/S Synthesis of oligosaccharides
WO2019169188A1 (en) * 2018-02-28 2019-09-06 The Regents Of The University Of California Methods and therapies for treating atherosclerosis and/or hyperlipidemia using oligosaccharides
EP4025072B1 (en) 2019-09-04 2025-08-20 Inbiose N.V. Process for removing an antifoam agent from a solution comprising a human milk oligosaccharide and related compositions
CN115703772B (zh) * 2021-08-09 2024-07-30 天地恒一制药股份有限公司 艾拉莫德共晶，及其制备方法与应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012522761A (ja) 2009-04-06 2012-09-27 イナルコ ソシエタ ペル アチオニ ６’−シアリルラクトース塩並びに６’−シアリルラクトース塩及び他のａ−シアリルオリゴ糖の合成方法
JP2013519694A (ja) 2010-02-19 2013-05-30 グリコム・アクティーゼルスカブ ６’−ｏ−シアリルラクトースおよび中間体の製造

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5575916A (en) 1994-11-07 1996-11-19 Neose Pharmaceuticals, Inc. Method of processing a cheese processing waste stream
JP4082746B2 (ja) 1995-03-20 2008-04-30 雪印乳業株式会社 シアリルラクトースの分離方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012522761A (ja) 2009-04-06 2012-09-27 イナルコ ソシエタ ペル アチオニ ６’−シアリルラクトース塩並びに６’−シアリルラクトース塩及び他のａ−シアリルオリゴ糖の合成方法
JP2013519694A (ja) 2010-02-19 2013-05-30 グリコム・アクティーゼルスカブ ６’−ｏ−シアリルラクトースおよび中間体の製造

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Ｃａｒｂｏｈｙｄｒａｔｅ Ｒｅｓｅａｒｃｈ、（２００２）、３３７、ｐｐ．４７３－４８３
社団法人日本化学会編、第４版 実験化学講座１ 基本操作Ｉ、丸善株式会社、１９９６年４月５日第２刷発行、ｐｐ．１８４－１８９

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JP2022069548A (ja) 2022-05-11
US10745432B2 (en) 2020-08-18
JP2021036002A (ja) 2021-03-04
EP3378868A1 (en) 2018-09-26
US20180305388A1 (en) 2018-10-25
JPWO2017086443A1 (ja) 2018-08-30
EP3378868A4 (en) 2019-04-17
WO2017086443A1 (ja) 2017-05-26

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