JP7254835B2 - 配合剤送達装置 - Google Patents
配合剤送達装置 Download PDFInfo
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- JP7254835B2 JP7254835B2 JP2020563421A JP2020563421A JP7254835B2 JP 7254835 B2 JP7254835 B2 JP 7254835B2 JP 2020563421 A JP2020563421 A JP 2020563421A JP 2020563421 A JP2020563421 A JP 2020563421A JP 7254835 B2 JP7254835 B2 JP 7254835B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/065—Rigid ampoules, e.g. glass ampoules
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
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- A—HUMAN NECESSITIES
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
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- A61J1/16—Holders for containers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2058—Connecting means having multiple connecting ports
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/002—Compounding apparatus specially for enteral or parenteral nutritive solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
- A61M5/1409—Infusion of two or more substances in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1413—Modular systems comprising interconnecting elements
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/04—Tools for specific apparatus
- A61M2209/045—Tools for specific apparatus for filling, e.g. for filling reservoirs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
- A61M5/1408—Infusion of two or more substances in parallel, e.g. manifolds, sequencing valves
Description
Claims (11)
- 所定の選択された複数の薬剤成分を送達するための配合剤送達装置であって、
前記複数の薬剤成分の各々は薬剤バイアルに収容され、
前記装置は、複数のモジュールと、ベーストレイとを備え、
前記複数のモジュールの各々は、
薬剤バイアルを収容するように形成される内部空間を包括的に定義する本体及び蓋と、
移動可能に前記内部空間に配置されるスパイクプレートであって、前記スパイクプレートは自由端で終了する突出するカニューレ及び第1及び第2ポートを有し、第1及び第2開口は前記自由端に形成され、第1及び第2ルーメンはそれぞれ前記自由端から延びて前記カニューレを通って前記第1及び第2ポートで終了する、スパイクプレートと、
を有し、
前記ベーストレイは、
各々、前記複数のモジュールの一つを挿入式で受けるように形成される複数の穴を規定する骨格と、
前記複数の穴の各々において、対応する穴で受けたモジュールの前記第1及び第2ポートに通じるように形成される第1及び第2注入口と、
特定の穴の前記第2注入口を前記特定の穴に隣接する穴の前記第1注入口に接続して、流体がこれらの間で流れるようにする通路と、
を有し、
前記複数の穴のそれぞれにおいて、前記第1及び第2注入口は、対応するモジュールの前記スパイクプレートを、前記モジュールが穴に挿入された状態で、静止位置に維持するように構成される、
配合剤送達装置。 - 前記複数のモジュールから前記複数の薬剤成分を引き出すための負圧源を更に備える、
請求項1に記載の配合剤送達装置。 - 前記ベーストレイは、ハウジングを備え、
前記負圧源は、前記ハウジング内に配置される、
請求項2に記載の配合剤送達装置。 - 前記スパイクプレートは、全てが前記内部空間に配置される、
請求項1に記載の配合剤送達装置。 - 前記蓋は、開口を有する、
請求項1~4のいずれか一つに記載の配合剤送達装置。 - 前記スパイクプレートは、前記開口の近くの初期状態から前記開口から離れた前記内部空間内に前記蓋に対して移動可能である、
請求項5に記載の配合剤送達装置。 - 前記複数の穴の各々において、対応するモジュールが穴に挿入されると、前記第1及び第2注入口が前記開口を通して前記スパイクプレートの前記第1及び第2ポートに結合して、それらの間に封止された流体流路を形成する、
請求項5又は6に記載の配合剤送達装置。 - 対応するモジュールの前記スパイクプレートが前記静止位置にあり、前記モジュールが前記穴に挿入されると、対応するモジュールにおいて、前記蓋が、前記スパイクプレートに対して移動して、前記スパイクプレートを前記蓋の前記開口から離れるように移動させる、
請求項5~7のいずれか一つに記載の配合剤送達装置。 - 前記スパイクプレートは、初期状態において、解放可能に保持される、
請求項1~8のいずれか一つに記載の配合剤送達装置。 - 前記複数のモジュールの少なくとも一つは、前記内部空間に収容される薬剤バイアルを更に備え、
前記薬剤バイアルは、隔壁を有し、
対応するモジュールを穴に十分に挿入すると、前記スパイクプレートの前記カニューレが前記薬剤バイアルの前記隔壁を完全に貫通する、
請求項1~9のいずれか一つに記載の配合剤送達装置。 - 前記蓋は、ヒンジ構造で前記本体に取り付けられる、
請求項1~10のいずれか一つに記載の配合剤送達装置。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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JP2023053052A JP7434636B2 (ja) | 2018-05-11 | 2023-03-29 | 配合剤送達装置 |
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US201862670266P | 2018-05-11 | 2018-05-11 | |
US62/670,266 | 2018-05-11 | ||
PCT/US2019/031791 WO2019217864A1 (en) | 2018-05-11 | 2019-05-10 | Combinatorial drug delivery device |
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JP2023053052A Division JP7434636B2 (ja) | 2018-05-11 | 2023-03-29 | 配合剤送達装置 |
Publications (2)
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JP2021522927A JP2021522927A (ja) | 2021-09-02 |
JP7254835B2 true JP7254835B2 (ja) | 2023-04-10 |
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JP2020563437A Pending JP2021522929A (ja) | 2018-05-11 | 2019-05-10 | 配合剤送達装置用の直列接続可能な薬剤モジュール |
JP2020563421A Active JP7254835B2 (ja) | 2018-05-11 | 2019-05-10 | 配合剤送達装置 |
JP2020563440A Pending JP2021523774A (ja) | 2018-05-11 | 2019-05-10 | 併用療法の送達のための装置及びシステム |
JP2023053052A Active JP7434636B2 (ja) | 2018-05-11 | 2023-03-29 | 配合剤送達装置 |
JP2023079258A Pending JP2023099218A (ja) | 2018-05-11 | 2023-05-12 | 併用療法の送達のための装置及びシステム |
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JP2020563437A Pending JP2021522929A (ja) | 2018-05-11 | 2019-05-10 | 配合剤送達装置用の直列接続可能な薬剤モジュール |
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JP2023053052A Active JP7434636B2 (ja) | 2018-05-11 | 2023-03-29 | 配合剤送達装置 |
JP2023079258A Pending JP2023099218A (ja) | 2018-05-11 | 2023-05-12 | 併用療法の送達のための装置及びシステム |
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US (5) | US11944588B2 (ja) |
EP (6) | EP3790524B1 (ja) |
JP (5) | JP2021522929A (ja) |
KR (3) | KR20210006911A (ja) |
CN (3) | CN112118821A (ja) |
WO (3) | WO2019217864A1 (ja) |
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KR20210006911A (ko) * | 2018-05-11 | 2021-01-19 | 브리스톨-마이어스 스큅 컴퍼니 | 조합 약물 전달 장치 |
US20220370289A1 (en) * | 2019-11-08 | 2022-11-24 | Bristol-Myers Squibb Company | Alternative fluidic pathing for serially connectable drug modules |
KR20220097452A (ko) | 2019-11-08 | 2022-07-07 | 브리스톨-마이어스 스큅 컴퍼니 | 조합적 약물 전달 기기에서 직렬로 연결된 약물 모듈의 정확도를 검증하기 위한 시스템 |
KR102561236B1 (ko) * | 2021-02-09 | 2023-07-28 | 윤지영 | 바이알 홀더 및 이를 포함하는 바이알 홀더 패키지 |
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