JP7248588B2 - 疾患の治療のためのｋｌｋ５アンタゴニストの使用 - Google Patents

疾患の治療のためのｋｌｋ５アンタゴニストの使用 Download PDF

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JP7248588B2
JP7248588B2 JP2019556809A JP2019556809A JP7248588B2 JP 7248588 B2 JP7248588 B2 JP 7248588B2 JP 2019556809 A JP2019556809 A JP 2019556809A JP 2019556809 A JP2019556809 A JP 2019556809A JP 7248588 B2 JP7248588 B2 JP 7248588B2
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klk5
antibody
asthma
binding
human
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JP2020517628A (ja
JP2020517628A5 (https=
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エイミー ドレッセン，
デーヴィッド ビー． イーアエア，
ムーレイ ヒシャム アラウイ イスマーイール，
ジャネット ケー． ジャックマン，
ロバート エー． ラザラス，
ケリー ロイット，
ヘンリー アール． マウン，
ブライアン エル． ヤスパン，
タンション イー，
ジョーセフ アール． アーロン，
ヒルダ ワイ． ヘルナンデス－バリー，
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Genentech Inc
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Genentech Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P11/06—Antiasthmatics
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8135—Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid
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    • C12N9/14—Hydrolases (3)
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JP2019556809A 2017-04-21 2018-04-20 疾患の治療のためのｋｌｋ５アンタゴニストの使用 Active JP7248588B2 (ja)

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US201762488515P 2017-04-21 2017-04-21
US62/488,515 2017-04-21
PCT/US2018/028637 WO2018195472A1 (en) 2017-04-21 2018-04-20 Use of klk5 antagonists for treatment of a disease

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US (2) US20190078160A1 (https=)
EP (1) EP3624820A1 (https=)
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KR (1) KR20190141686A (https=)
CN (1) CN110536691A (https=)
AU (1) AU2018254586A1 (https=)
CA (1) CA3059615A1 (https=)
CR (1) CR20190480A (https=)
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AU2019346549B2 (en) 2018-09-24 2024-09-12 Krystal Biotech, Inc. Compositions and methods for the treatment of Netherton Syndrome
JP6888175B2 (ja) 2018-11-07 2021-06-16 第一三共株式会社 Ｋｌｋ５阻害ペプチド
US20210000949A1 (en) * 2019-05-01 2021-01-07 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-33 antagonist
BR112022000740A2 (pt) 2019-07-16 2022-07-05 Sanofi Biotechnology Métodos para tratamento ou prevenção de asma por administração de um antagonista de il-4r
PH12022550646A1 (en) 2019-09-18 2023-04-03 Genentech Inc Anti-klk7 antibodies, anti-klk5 antibodies, multispecific anti-klk5/klk7 antibodies, and methods of use
WO2021092043A1 (en) * 2019-11-04 2021-05-14 Azitra Inc Compositions and methods for treatment of cancer with lekti
GB202001447D0 (en) * 2020-02-03 2020-03-18 Ucb Biopharma Sprl Antibodies
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