JP7212678B2 - 診断用デバイスおよびシステム - Google Patents

診断用デバイスおよびシステム Download PDF

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JP7212678B2
JP7212678B2 JP2020515881A JP2020515881A JP7212678B2 JP 7212678 B2 JP7212678 B2 JP 7212678B2 JP 2020515881 A JP2020515881 A JP 2020515881A JP 2020515881 A JP2020515881 A JP 2020515881A JP 7212678 B2 JP7212678 B2 JP 7212678B2
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beads
diagnostic device
portable diagnostic
assay
sample
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JP2020533993A5 (enExample
JP2020533993A (ja
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オファレル，ブライアン
オサリバン，キアン・デスモンド
オドリスコル，ジョン
カミンズ，ティモシー
フリー，ポール
マッカーシー，モイラ
ウォルシュ，ジョン
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アルトラテック・リミテッド
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Priority claimed from EP17192156.2A external-priority patent/EP3460077B1/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2547/00—Reactions characterised by the features used to prevent contamination
    • C12Q2547/10—Reactions characterised by the features used to prevent contamination the purpose being preventing contamination
    • C12Q2547/107—Use of permeable barriers, e.g. waxes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/143—Magnetism, e.g. magnetic label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/149—Particles, e.g. beads

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Fluid Mechanics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
JP2020515881A 2017-09-20 2018-09-06 診断用デバイスおよびシステム Active JP7212678B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP17192153 2017-09-20
EP17192156.2A EP3460077B1 (en) 2017-09-20 2017-09-20 Diagnostic device and system
EP17192153.9 2017-09-20
EP17192156.2 2017-09-20
EP17202859 2017-11-21
EP17202859.9 2017-11-21
PCT/EP2018/074058 WO2019057515A1 (en) 2017-09-20 2018-09-06 DIAGNOSTIC SYSTEM AND DEVICE

Publications (3)

Publication Number Publication Date
JP2020533993A JP2020533993A (ja) 2020-11-26
JP2020533993A5 JP2020533993A5 (enExample) 2021-07-26
JP7212678B2 true JP7212678B2 (ja) 2023-01-25

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JP2020515881A Active JP7212678B2 (ja) 2017-09-20 2018-09-06 診断用デバイスおよびシステム

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US (3) US11459601B2 (enExample)
EP (2) EP4219751A1 (enExample)
JP (1) JP7212678B2 (enExample)
CN (1) CN111108216B (enExample)
WO (1) WO2019057515A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3080294B1 (en) 2013-12-12 2018-06-13 Altratech Limited A capacitive sensor and method of use
WO2015086652A1 (en) 2013-12-12 2015-06-18 Altra Tech Limited A sample preparation method and apparatus
WO2019057515A1 (en) 2017-09-20 2019-03-28 Altratech Limited DIAGNOSTIC SYSTEM AND DEVICE
CN120082430A (zh) * 2020-06-19 2025-06-03 中国疾病预防控制中心病毒病预防控制所 一种样品处理及检测装置
KR102682605B1 (ko) * 2021-11-03 2024-07-09 주식회사 위즈바이오솔루션 일체형 분자 진단 장치 및 이를 이용한 분자 진단 방법
JP2025504676A (ja) * 2022-01-28 2025-02-14 アルトラテック・リミテッド 微生物学的用途のための単一ビーズ静電容量検出器
CN115646562B (zh) * 2022-09-27 2023-08-11 郑州大学 基于微磁作用的操控芯片、检测组件和检测系统、方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011516034A (ja) 2008-02-29 2011-05-26 ノースウエスタン ユニバーシティ 生物反応促進用バリア
JP2015084657A (ja) 2013-10-28 2015-05-07 セイコーエプソン株式会社 核酸抽出用デバイス

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213825A3 (en) 1985-08-22 1989-04-26 Molecular Devices Corporation Multiple chemically modulated capacitance
US4822566A (en) 1985-11-19 1989-04-18 The Johns Hopkins University Optimized capacitive sensor for chemical analysis and measurement
WO1988010272A1 (en) 1987-06-26 1988-12-29 Garth Alexander Nicholson Method of preserving a body fluid sample, prior to assay for hiv (aids) infection
US5139685A (en) 1991-03-26 1992-08-18 Gds Technology, Inc. Blood separation filter assembly and method
US5413924A (en) 1992-02-13 1995-05-09 Kosak; Kenneth M. Preparation of wax beads containing a reagent for release by heating
US5378879A (en) 1993-04-20 1995-01-03 Raychem Corporation Induction heating of loaded materials
US5679519A (en) 1995-05-09 1997-10-21 Oprandy; John J. Multi-label complex for enhanced sensitivity in electrochemiluminescence assay
US6391265B1 (en) 1996-08-26 2002-05-21 Biosite Diagnostics, Inc. Devices incorporating filters for filtering fluid samples
SE9703314D0 (sv) 1997-09-15 1997-09-15 Sangtec Medical Ab Capacity affinity sensor
DE19822123C2 (de) 1997-11-21 2003-02-06 Meinhard Knoll Verfahren und Vorrichtung zum Nachweis von Analyten
US6022324A (en) 1998-01-02 2000-02-08 Skinner; Bruce A. J. Biopsy instrument
AU1241000A (en) 1998-10-27 2000-05-15 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
WO2000039335A1 (en) 1998-12-24 2000-07-06 Aclara Biosciences, Inc. Individually addressable solid surfaces for multiplexed operations
EP1212458A4 (en) 1999-07-30 2005-01-05 Surromed Inc INSTRUMENTS, METHODS AND REAGENTS FOR PLASMON SURFACE RESONANCE
US20060091006A1 (en) 1999-11-04 2006-05-04 Yi Wang Analyte sensor with insertion monitor, and methods
US6962906B2 (en) 2000-03-14 2005-11-08 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
US20040005582A1 (en) 2000-08-10 2004-01-08 Nanobiodynamics, Incorporated Biospecific desorption microflow systems and methods for studying biospecific interactions and their modulators
AUPR142500A0 (en) 2000-11-13 2000-12-07 Human Genetic Signatures Pty Ltd A peptide nucleic acid-based assay for the detection of specific nucleic acid sequences
KR20020063359A (ko) 2001-01-27 2002-08-03 일렉트론 바이오 (주) 핵산 및 올리거뉴클레오티드의 상보적 이중결합의 특정서열에 특이적으로 반응하는 절단기법을 이용한 핵산 혼성분석 방법 및 장치
US6428962B1 (en) 2001-02-12 2002-08-06 Dna Analysis, Inc. Nucleic acid collection barrier method and apparatus
US20020168663A1 (en) 2001-02-27 2002-11-14 Phan Brigitte Chau Methods for DNA conjugation onto solid phase including related optical biodiscs and disc drive systems
US20060040286A1 (en) 2001-03-28 2006-02-23 Nanosphere, Inc. Bio-barcode based detection of target analytes
US20040023253A1 (en) 2001-06-11 2004-02-05 Sandeep Kunwar Device structure for closely spaced electrodes
AU2002329186A1 (en) 2001-06-21 2003-01-08 Virginia Tech Intellectual Properties, Inc. Electro-optical detection device
US20050101841A9 (en) 2001-12-04 2005-05-12 Kimberly-Clark Worldwide, Inc. Healthcare networks with biosensors
US7691326B2 (en) 2002-01-04 2010-04-06 Sorenson Genomics, L.L.C. System for non-invasive extraction, secure handling and storage and facile processing and facile processing of a specimen
US8154093B2 (en) 2002-01-16 2012-04-10 Nanomix, Inc. Nano-electronic sensors for chemical and biological analytes, including capacitance and bio-membrane devices
JP3810713B2 (ja) 2002-07-25 2006-08-16 独立行政法人科学技術振興機構 抗原抗体反応検出方法及び装置
US7176036B2 (en) 2002-09-20 2007-02-13 Arrowhead Center, Inc. Electroactive microspheres and methods
FI120863B (fi) 2002-10-18 2010-04-15 Biocontrol Systems Inc Magneettinen siirtomenetelmä ja mikropartikkelien siirtolaite
EP1603674B1 (en) 2003-02-05 2016-01-06 Iquum, Inc. Sample processing
DE10319155B4 (de) 2003-04-29 2008-02-14 Bruker Daltonik Gmbh Elektrisch auslesbare Bindungen von Analytmolekülen an immobilisierten Sondenmolekülen
KR20060052889A (ko) 2003-07-30 2006-05-19 코닌클리케 필립스 일렉트로닉스 엔.브이. 생체 활성 분자 사이의 결합을 결정하기 위한 자기 입자의사용
GB0319671D0 (en) 2003-08-21 2003-09-24 Secr Defence Apparatus for processing a fluid sample
US20050069905A1 (en) 2003-09-30 2005-03-31 Carl Myerholtz Detection of molecular binding events
US7554134B2 (en) 2004-04-02 2009-06-30 ChipSensors Limited Integrated CMOS porous sensor
CA2506961C (en) 2004-05-11 2013-05-07 Inrad, Inc. Core biopsy device
US7785785B2 (en) 2004-11-12 2010-08-31 The Board Of Trustees Of The Leland Stanford Junior University Charge perturbation detection system for DNA and other molecules
US20060205061A1 (en) 2004-11-24 2006-09-14 California Institute Of Technology Biosensors based upon actuated desorption
CA2592204C (en) 2004-12-23 2013-03-12 I-Stat Corporation Nucleic acid diagnostics system and methods
DE102005029809B4 (de) 2005-06-27 2007-04-26 Siemens Ag Vorrichtung und Verfahren zur Aufbereitung einer Probe für eine Analyse und Vorrichtung und Verfahren zur Analyse einer Probe
ES2301296B1 (es) 2005-09-16 2009-05-29 Consejo Superior Investig. Cientificas Manoparticula biosensora, procedimiento de elaboracion y sus aplicaciones.
US8841069B2 (en) 2005-12-29 2014-09-23 Korea Materials & Analysis Corporation Dendron-mediated DNA virus detection
WO2007106580A2 (en) 2006-03-15 2007-09-20 Micronics, Inc. Rapid magnetic flow assays
AU2007334393A1 (en) 2006-12-14 2008-06-26 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale FET arrays
US7993525B2 (en) 2006-12-29 2011-08-09 Intel Corporation Device and method for particle complex handling
JP2008167722A (ja) 2007-01-15 2008-07-24 Konica Minolta Medical & Graphic Inc 磁性支持体上での加熱による核酸単離方法
JP5026873B2 (ja) 2007-07-04 2012-09-19 株式会社船井電機新応用技術研究所 酵素電極、酵素電極の製造方法及び酵素センサ
EP2172564A1 (en) 2008-10-06 2010-04-07 Sony Corporation A method of derivatising an analyte for subsequent detection through a nucleic acid based sensor
US8106428B2 (en) 2009-03-03 2012-01-31 Board Of Regents, The University Of Texas System Nano-scale bridge biosensors
EP2233920B1 (en) 2009-03-27 2017-08-16 ams international AG A sensor device and a method of manufacturing the same
GB2469071A (en) 2009-03-31 2010-10-06 Diamatrix Ltd Electrochemical test device
US9005987B2 (en) 2009-04-16 2015-04-14 University Of Southern California Methods for quantitative target detection and related devices and systems
EP2429704A2 (en) 2009-05-14 2012-03-21 Streck Inc. Sample processing cassette, system, and method
EP2462051A4 (en) 2009-08-07 2013-06-26 Nanomix Inc MAGNETIC CARBON NANOTUBES BASED BIO RECOGNITION
US8202693B2 (en) 2009-11-24 2012-06-19 Omega Bio-Tek, Inc. Method of isolation of nucleic acids
US20130045267A1 (en) 2010-02-05 2013-02-21 University Of Rochester Methods of using agents that modulate claudin expression
US20130240376A1 (en) 2010-09-02 2013-09-19 Heed Diagnostics Aps Electrochemical detection of analyte
EP2670311A1 (en) 2011-01-31 2013-12-11 Boston Scientific Scimed, Inc. Distal tip configurations for biopsy with eus fna
CN103299179A (zh) 2011-06-06 2013-09-11 松下电器产业株式会社 焦磷酸的测定方法以及snp分型方法
KR101542549B1 (ko) 2011-09-02 2015-08-06 산디아 코포레이션 바이오센싱 및 약물 전달을 위한 마이크로니들 어레이
WO2015086652A1 (en) * 2013-12-12 2015-06-18 Altra Tech Limited A sample preparation method and apparatus
EP2883961B8 (en) 2013-12-12 2017-09-27 Altratech Limited A nucleic acid analysis method and apparatus
EP3080294B1 (en) 2013-12-12 2018-06-13 Altratech Limited A capacitive sensor and method of use
EP3230710B1 (en) 2014-12-10 2023-06-07 Altratech Limited A sampling apparatus
CN108463719B (zh) 2015-12-28 2021-12-21 生命扫描苏格兰有限公司 具有电极电压感测连接件的基于电化学的分析测试条以及与其一起使用的手持式测试仪
WO2019057513A1 (en) 2017-09-20 2019-03-28 University College Cork - National University Of Ireland, Cork DIAGNOSTIC SENSOR
WO2019057515A1 (en) 2017-09-20 2019-03-28 Altratech Limited DIAGNOSTIC SYSTEM AND DEVICE

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011516034A (ja) 2008-02-29 2011-05-26 ノースウエスタン ユニバーシティ 生物反応促進用バリア
JP2015084657A (ja) 2013-10-28 2015-05-07 セイコーエプソン株式会社 核酸抽出用デバイス

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US20200216884A1 (en) 2020-07-09
US20240218429A1 (en) 2024-07-04
CN111108216A (zh) 2020-05-05
EP4219751A1 (en) 2023-08-02
EP3684950B1 (en) 2023-04-26
US20230094539A1 (en) 2023-03-30
JP2020533993A (ja) 2020-11-26
US11459601B2 (en) 2022-10-04
WO2019057515A1 (en) 2019-03-28
EP3684950A1 (en) 2020-07-29
CN111108216B (zh) 2024-02-23

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