JP7176736B2 - 合成のクモドラグラインシルクを含む複合材料 - Google Patents

合成のクモドラグラインシルクを含む複合材料 Download PDF

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JP7176736B2
JP7176736B2 JP2018541640A JP2018541640A JP7176736B2 JP 7176736 B2 JP7176736 B2 JP 7176736B2 JP 2018541640 A JP2018541640 A JP 2018541640A JP 2018541640 A JP2018541640 A JP 2018541640A JP 7176736 B2 JP7176736 B2 JP 7176736B2
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fibers
proteins
polymer
protein
cell
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JP2019510541A (ja
JP2019510541A5 (OSRAM
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イッタ,シュムリク
シメル,メニ
スクラン,エラ
ステルン,ドガニット
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シービックス マテリアル サイエンシーズ リミテッド
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    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00Formation of filaments, threads, or the like
    • D01D5/0007Electro-spinning
    • D01D5/0015Electro-spinning characterised by the initial state of the material
    • D01D5/003Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion
    • D01D5/0038Electro-spinning characterised by the initial state of the material the material being a polymer solution or dispersion the fibre formed by solvent evaporation, i.e. dry electro-spinning
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00General methods for the manufacture of artificial filaments or the like
    • D01F1/02Addition of substances to the spinning solution or to the melt
    • D01F1/10Other agents for modifying properties
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • D01F4/02Monocomponent artificial filaments or the like of proteins; Manufacture thereof from fibroin
    • DTEXTILES; PAPER
    • D01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01FCHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/88Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2211/00Protein-based fibres, e.g. animal fibres
    • D10B2211/01Natural animal fibres, e.g. keratin fibres
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2211/00Protein-based fibres, e.g. animal fibres
    • D10B2211/01Natural animal fibres, e.g. keratin fibres
    • D10B2211/04Silk
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/02Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyamides
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/04Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyesters, e.g. polyethylene terephthalate [PET]
    • D10B2331/041Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyesters, e.g. polyethylene terephthalate [PET] derived from hydroxy-carboxylic acids, e.g. lactones
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2331/00Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products
    • D10B2331/10Fibres made from polymers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polycondensation products polyurethanes
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00Physical properties
    • D10B2401/06Load-responsive characteristics
    • D10B2401/061Load-responsive characteristics elastic
    • DTEXTILES; PAPER
    • D10INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10BINDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00Physical properties
    • D10B2401/06Load-responsive characteristics
    • D10B2401/063Load-responsive characteristics high strength

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Textile Engineering (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Insects & Arthropods (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Manufacturing & Machinery (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Artificial Filaments (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
JP2018541640A 2016-02-11 2017-02-12 合成のクモドラグラインシルクを含む複合材料 Active JP7176736B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022176185A JP7529300B2 (ja) 2016-02-11 2022-11-02 合成のクモドラグラインシルクを含む複合材料

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662293880P 2016-02-11 2016-02-11
US62/293,880 2016-02-11
US201662317572P 2016-04-03 2016-04-03
US62/317,572 2016-04-03
ILPCT/IL2016/050874 2016-08-10
PCT/IL2016/050874 WO2017025964A1 (en) 2015-08-10 2016-08-10 Compositions and methods for fabricating synthetic dragline spider silk
PCT/IL2017/050175 WO2017138002A1 (en) 2016-02-11 2017-02-12 Composite materials comprising synthetic dragline spider silk

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JP2019510541A JP2019510541A (ja) 2019-04-18
JP2019510541A5 JP2019510541A5 (OSRAM) 2020-03-26
JP7176736B2 true JP7176736B2 (ja) 2022-11-22

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US (2) US11345727B2 (OSRAM)
EP (2) EP4375403A3 (OSRAM)
JP (2) JP7176736B2 (OSRAM)
KR (1) KR102790669B1 (OSRAM)
CN (1) CN109477252A (OSRAM)
AU (1) AU2017218794B2 (OSRAM)
BR (1) BR112018016472A2 (OSRAM)
CA (1) CA3014537A1 (OSRAM)
WO (1) WO2017138002A1 (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7176736B2 (ja) 2016-02-11 2022-11-22 シービックス マテリアル サイエンシーズ リミテッド 合成のクモドラグラインシルクを含む複合材料
WO2019054481A1 (ja) * 2017-09-14 2019-03-21 バンドー化学株式会社 ゴム組成物及びそれを用いた伝動ベルト
ES3028254T3 (en) * 2018-04-03 2025-06-18 Hasetora Spinning Co Ltd Blended yarn, knitted/woven body of same, and method for manufacturing said knitted/woven body
US12202864B2 (en) 2018-10-31 2025-01-21 University Of Massachusetts Silk nucleotides and proteins and methods of use
WO2020183465A1 (en) * 2019-03-11 2020-09-17 Seevix Material Sciences Ltd. Compositions comprising dragline spider silk
KR20220029660A (ko) * 2019-07-04 2022-03-08 시비스 머테리얼 사이언스 리미티드 원핵생물 발현 시스템 및 이의 사용 방법
TW202144386A (zh) * 2020-02-12 2021-12-01 美商保爾特紡織品公司 重組絲固體及膜
US20230310712A1 (en) * 2020-03-18 2023-10-05 Takeda Pharmaceutical Company Limited Implantable cell chamber device and uses thereof
AU2021259692A1 (en) 2020-04-23 2022-10-27 Seevix Material Sciences Ltd. Cosmetic compositions comprising dragline spider silk
US11732238B2 (en) 2020-05-04 2023-08-22 University Of Connecticut Main-chain liquid crystalline hydrogels for cell culture
EP4161094A4 (en) 2020-06-02 2024-07-03 Foster Electric Company, Limited ELECTRO-ACOUSTIC TRANSDUCER MEMBRANE
AU2021304486A1 (en) * 2020-07-05 2023-02-02 Seevix Material Sciences Ltd. Highly porous spider silk fibers
US12024540B2 (en) * 2021-05-20 2024-07-02 Samsung Electronics Co., Ltd. Polypetide, photoresist composition including the same, and method of forming pattern using the same
CN113668142B (zh) * 2021-09-29 2022-11-04 广州市醒目医药科技有限公司 医疗卫生用抗菌无纺布及生产方法
KR20230083100A (ko) 2021-12-02 2023-06-09 삼성전자주식회사 폴리펩티드, 이를 포함하는 포토레지스트 조성물 및 이를 이용한 패턴 형성 방법
EP4486762A1 (en) * 2022-03-04 2025-01-08 Anna Rising Recombinant spider silk proteins
CN116376070A (zh) * 2023-01-10 2023-07-04 无锡祺杰科技有限公司 一种强度高弹性拉力大的pe缠绕膜生产方法
KR102640338B1 (ko) * 2023-04-19 2024-02-23 김홍수 균열 저항성이 우수한 마이크로 콘크리트 보수 모르타르 조성물 및 이를 이용한 콘크리트 구조물의 보수 시공방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004090205A2 (en) 2003-04-03 2004-10-21 Nexia Biotechnologies, Inc. Method and apparatus for spinning spider silk protein
JP2008507260A (ja) 2004-06-25 2008-03-13 テヒニシェ ウニヴェルズィテート ミュンヘン 天然起源のタンパク質およびそれから作られる材料
WO2011113592A1 (en) 2010-03-17 2011-09-22 Amsilk Gmbh Method for production of polymer containing fibres
US20120022005A1 (en) 2010-05-24 2012-01-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Synthetic Dragline Spider Silk-Like Proteins
JP2015532690A (ja) 2012-09-06 2015-11-12 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755560A (en) 1971-06-30 1973-08-28 Dow Chemical Co Nongreasy cosmetic lotions
US4421769A (en) 1981-09-29 1983-12-20 The Procter & Gamble Company Skin conditioning composition
US5011681A (en) 1989-10-11 1991-04-30 Richardson-Vicks, Inc. Facial cleansing compositions
AU2002306944A1 (en) 2001-08-29 2003-03-18 University Of Wyoming Spider silk protein encoding nucleic acids, polypeptides, antibodies and method of use thereof
AU2003202949A1 (en) 2002-01-11 2003-07-30 Ali Alwattari Methods and apparatus for spinning spider silk protein
AU2003249366A1 (en) 2002-06-24 2004-01-06 Tufts University Silk biomaterials and methods of use thereof
US8030024B2 (en) 2004-06-25 2011-10-04 Amsilk Gmbh Synthesis of spider dragline and/or flagelliform proteins
CN103320738A (zh) 2004-06-29 2013-09-25 塔塔钢铁艾默伊登有限责任公司 具有热浸镀锌合金镀层的钢片及其制备方法
PL1773875T3 (pl) 2004-07-22 2015-03-31 Amsilk Gmbh Rekombinowane białka jedwabiu pająków
AU2006286753B2 (en) 2005-08-29 2011-08-18 Amsilk Gmbh Modified spider silk proteins
EP2899204B1 (en) 2005-12-30 2017-06-28 Spiber Technologies AB Support for cell culture comprising spider silk proteins and methods for producing the same
KR100894265B1 (ko) 2007-06-05 2009-04-21 재단법인서울대학교산학협력재단 골형성 촉진 펩타이드를 함유하는 주입형 골재생재
AU2008345047A1 (en) 2007-12-26 2009-07-09 Gel-Del Technologies, Inc. Biocompatible protein particles, particle devices and methods thereof
US20110189292A1 (en) 2009-04-20 2011-08-04 Allergan, Inc. Dermal fillers comprising silk fibroin hydrogels and uses thereof
US20110008437A1 (en) 2009-04-20 2011-01-13 Altman Gregory H Silk Fibroin Hydrogels and Uses Thereof
EP2506837B1 (en) 2009-11-30 2020-07-01 Amsilk GmbH Spider silk particles for controlled and sustained delivery of compounds
EP3495381A1 (en) 2009-12-08 2019-06-12 AMSilk GmbH Silk protein coatings
JP5691052B2 (ja) 2010-09-10 2015-04-01 岡本株式会社 組換え生物及び組換え生物により作られるタンパク質
CN102475909A (zh) 2010-11-22 2012-05-30 大连创达技术交易市场有限公司 一种组织工程用多孔支架材料
RU2451023C1 (ru) 2010-11-25 2012-05-20 Владимир Григорьевич Богуш Способ получения рекомбинантного белка паутины, слитый белок, рекомбинантная днк, вектор экспрессии, клетка-хозяин и штаммы-продуценты
EP2681280B1 (en) 2011-02-28 2019-04-10 The Royal Institution for the Advancement of Learning / McGill University Biomaterial, method for making the biomaterial and uses of the same
DE102011105372A1 (de) 2011-06-20 2012-12-20 Carl Freudenberg Kg Stabile, wässrige Protein-Lösung oder Protein-Dispersion, Verfahren zur Herstellung der stabilen, wässrigen Lösung oder Dispersion und Verfahren zur Herstellung von Form-oder Flächengebilden, Imprägnierungen oder Beschichtungen aus der stabilen, wässrigen Protein-Lösung oder Protein-Dispersion sowie deren Verwendung
JP6362540B2 (ja) 2011-11-09 2018-07-25 トラスティーズ・オブ・タフツ・カレッジTrustees Of Tufts College 注射可能なシルクフィブロイン粒子およびその使用
NL1039495C2 (nl) 2012-03-27 2013-09-30 Jalila Essaidi Werkwijze ter vervaardiging van een huidsubstituut op basis van spinnenzijde alsmede draagstructuur vervaardigd onder toepassing van deze werkwijze en draagstructuur met doorgroeiende levende huid.
US9925301B2 (en) 2012-04-06 2018-03-27 Trustees Of Tufts College Methods of producing and using silk microfibers
WO2013164405A1 (en) 2012-05-02 2013-11-07 Spiber Technologies Ab Spider silk fusion protein structures without repetitive fragment for binding to an organic target
US20150183841A1 (en) 2012-07-09 2015-07-02 Trustees Of Tufts College High molecular weight silk fibroin and uses thereof
EP3412682B1 (en) 2013-03-15 2022-08-31 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
GB201416089D0 (en) 2014-09-11 2014-10-29 Univ Nottingham Modified spider silk
WO2016057851A1 (en) 2014-10-08 2016-04-14 Lewis Randolph V Expression systems and associated methods
WO2016164923A1 (en) * 2015-04-10 2016-10-13 Lewis Randolph V Spider silk and synthetic polymer fiber blends
CA2995156C (en) * 2015-08-10 2021-06-01 Seevix Material Sciences Ltd. Compositions and methods for fabricating synthetic dragline spider silk
JP7176736B2 (ja) 2016-02-11 2022-11-22 シービックス マテリアル サイエンシーズ リミテッド 合成のクモドラグラインシルクを含む複合材料
EP3549946A4 (en) 2016-11-29 2020-10-21 Spiber Inc. COMPOSITION OF PROTEIN, ITS PRODUCTION PROCESS AND PROCESS FOR IMPROVING THERMAL STABILITY
WO2019067737A1 (en) 2017-09-27 2019-04-04 Silk, Inc. MATERIALS COMPRISING RECOMBINANT SILK AND PROCESSES FOR PREPARING THE SAME
CN107595661B (zh) 2017-11-08 2020-09-15 海南蛛王生物科技有限公司 一种包含蜘蛛丝水解物的化妆品及其制备方法
WO2019094700A1 (en) 2017-11-10 2019-05-16 Cocoon Biotech Inc. Silk-based products and methods of use
MX2020004675A (es) 2017-11-10 2020-08-13 Givaudan Sa Formulaciones de alcohol de seda.
WO2020183465A1 (en) 2019-03-11 2020-09-17 Seevix Material Sciences Ltd. Compositions comprising dragline spider silk
WO2020184697A1 (ja) 2019-03-13 2020-09-17 国立研究開発法人農業・食品産業技術総合研究機構 繊維強化複合材料及びその製造方法
US20220177530A1 (en) 2019-03-27 2022-06-09 Evolved By Nature, Inc. Recombinant silk based products and methods of preparing the same
EP3978660A4 (en) 2019-05-29 2023-07-19 Spiber Inc. STRUCTURAL PROTEIN MICROBODY AND METHOD FOR PRODUCTION THEREOF, NANOFIBER PRODUCTION METHOD AND PROTEIN STRUCTURE PRODUCTION METHOD
KR20220029660A (ko) 2019-07-04 2022-03-08 시비스 머테리얼 사이언스 리미티드 원핵생물 발현 시스템 및 이의 사용 방법
AU2020315308A1 (en) 2019-07-12 2022-02-17 Bolt Threads, Inc. Recombinant spider silk extrudate formulations
JP2021054819A (ja) 2019-09-30 2021-04-08 Spiber株式会社 人工構造タンパク質繊維及びその製造方法
US20230339988A1 (en) 2019-12-18 2023-10-26 Liliana Patricia Ramirez Rios Metal Complexes Of Macrocycles And/Or Isoprenoids And/Or Linear Tetrapyrroles By Mechanochemistry (Grinding Or Milling), Preparation Method Thereof, Sunscreen/Concealer/UV Absorber Thereof, Self-Assembled Coating Material Thereof, Superamphiphilic Material Or Surfaces Thereof, Hair Dyeing Thereof And Other Uses Thereof
CN111214385B (zh) 2020-03-13 2022-05-17 珀莱雅化妆品股份有限公司 一种负载皮肤营养剂的纳米粒乳液及其制备方法
JP7508248B2 (ja) 2020-03-27 2024-07-01 株式会社コーセー 繊維含有化粧料
KR20230042091A (ko) 2020-07-23 2023-03-27 볼트 쓰레즈, 인크. 재조합 실크 조성물 및 이를 제조하는 방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004090205A2 (en) 2003-04-03 2004-10-21 Nexia Biotechnologies, Inc. Method and apparatus for spinning spider silk protein
JP2008507260A (ja) 2004-06-25 2008-03-13 テヒニシェ ウニヴェルズィテート ミュンヘン 天然起源のタンパク質およびそれから作られる材料
WO2011113592A1 (en) 2010-03-17 2011-09-22 Amsilk Gmbh Method for production of polymer containing fibres
US20120022005A1 (en) 2010-05-24 2012-01-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Synthetic Dragline Spider Silk-Like Proteins
JP2015532690A (ja) 2012-09-06 2015-11-12 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Biomaterials,2015年,Vol.48,p.137-146
J. Anat.,2015年,Vol.227, No.6,pp.746-756

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