JP7146286B2 - 多発性硬化症の進行を検出する、サブタイプ分類する、および/または評価するための、診断用バイオマーカー - Google Patents
多発性硬化症の進行を検出する、サブタイプ分類する、および/または評価するための、診断用バイオマーカー Download PDFInfo
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- JP7146286B2 JP7146286B2 JP2019562415A JP2019562415A JP7146286B2 JP 7146286 B2 JP7146286 B2 JP 7146286B2 JP 2019562415 A JP2019562415 A JP 2019562415A JP 2019562415 A JP2019562415 A JP 2019562415A JP 7146286 B2 JP7146286 B2 JP 7146286B2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/552—Glass or silica
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/285—Demyelinating diseases; Multipel sclerosis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762504130P | 2017-05-10 | 2017-05-10 | |
| US62/504,130 | 2017-05-10 | ||
| PCT/US2018/032130 WO2018209126A1 (en) | 2017-05-10 | 2018-05-10 | Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020519895A JP2020519895A (ja) | 2020-07-02 |
| JP2020519895A5 JP2020519895A5 (enExample) | 2021-07-26 |
| JP7146286B2 true JP7146286B2 (ja) | 2022-10-04 |
Family
ID=64104996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019562415A Active JP7146286B2 (ja) | 2017-05-10 | 2018-05-10 | 多発性硬化症の進行を検出する、サブタイプ分類する、および/または評価するための、診断用バイオマーカー |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20210003570A1 (enExample) |
| EP (1) | EP3622291A4 (enExample) |
| JP (1) | JP7146286B2 (enExample) |
| CA (1) | CA3062763A1 (enExample) |
| WO (1) | WO2018209126A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110186962B (zh) * | 2019-05-10 | 2021-06-25 | 天津大学 | 一种用于电容层析成像的不完整测量数据成像方法 |
| BR112023001788A2 (pt) * | 2020-08-03 | 2023-02-23 | Prevail Therapeutics Inc | Vetores aav que codificam parkina e usos da mesma |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013528799A (ja) | 2010-05-13 | 2013-07-11 | ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 神経変性疾患の検知および診断のための診断用自己抗体プロファイル |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US5856092A (en) | 1989-02-13 | 1999-01-05 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
| US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| ES2097925T3 (es) | 1991-09-18 | 1997-04-16 | Affymax Tech Nv | Metodo para sintetizar diversas colecciones de oligomeros. |
| US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
| WO1993009668A1 (en) | 1991-11-22 | 1993-05-27 | Affymax Technology N.V. | Combinatorial strategies for polymer synthesis |
| US5837832A (en) | 1993-06-25 | 1998-11-17 | Affymetrix, Inc. | Arrays of nucleic acid probes on biological chips |
| US6027880A (en) | 1995-08-02 | 2000-02-22 | Affymetrix, Inc. | Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis |
| US5861242A (en) | 1993-06-25 | 1999-01-19 | Affymetrix, Inc. | Array of nucleic acid probes on biological chips for diagnosis of HIV and methods of using the same |
| US5631734A (en) | 1994-02-10 | 1997-05-20 | Affymetrix, Inc. | Method and apparatus for detection of fluorescently labeled materials |
| US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| US6090555A (en) | 1997-12-11 | 2000-07-18 | Affymetrix, Inc. | Scanned image alignment systems and methods |
| US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
| EP0902885A4 (en) | 1996-05-16 | 2006-09-27 | Affymetrix Inc | SYSTEMS AND METHODS FOR DETECTION OF BRANDED PRODUCTS |
| WO1998041657A1 (en) | 1997-03-20 | 1998-09-24 | Affymetrix, Inc. | Iterative resequencing |
| US6201639B1 (en) | 1998-03-20 | 2001-03-13 | James W. Overbeck | Wide field of view and high speed scanning microscopy |
| US6185030B1 (en) | 1998-03-20 | 2001-02-06 | James W. Overbeck | Wide field of view and high speed scanning microscopy |
| US5936324A (en) | 1998-03-30 | 1999-08-10 | Genetic Microsystems Inc. | Moving magnet scanner |
| US6218803B1 (en) | 1999-06-04 | 2001-04-17 | Genetic Microsystems, Inc. | Position sensing with variable capacitance transducers |
| ATE467115T1 (de) | 2002-03-15 | 2010-05-15 | Affymetrix Inc | System und verfahren zur abtastung von biologischen materialien |
| US20050032074A1 (en) | 2002-09-09 | 2005-02-10 | Affymetrix, Inc. | Custom design method for resequencing arrays |
| US7300788B2 (en) | 2002-10-08 | 2007-11-27 | Affymetrix, Inc. | Method for genotyping polymorphisms in humans |
| DE60320828D1 (de) | 2002-11-07 | 2008-06-19 | Univ Erasmus | Fret proben und verfahren zur erkennung aufeinander einwirkeneden moleküle |
| US7317415B2 (en) | 2003-08-08 | 2008-01-08 | Affymetrix, Inc. | System, method, and product for scanning of biological materials employing dual analog integrators |
| WO2013010003A1 (en) | 2011-07-12 | 2013-01-17 | University Of Medicine And Dentistry Of New Jersey | Diagnostic biomarker profiles for the detection and diagnosis of alzheimer's disease |
| US9746482B2 (en) | 2011-08-11 | 2017-08-29 | Rowan University | Diagnostic biomarker profiles for the detection and diagnosis of parkinsons disease |
-
2018
- 2018-05-10 US US16/611,951 patent/US20210003570A1/en not_active Abandoned
- 2018-05-10 EP EP18798139.4A patent/EP3622291A4/en not_active Withdrawn
- 2018-05-10 WO PCT/US2018/032130 patent/WO2018209126A1/en not_active Ceased
- 2018-05-10 CA CA3062763A patent/CA3062763A1/en active Pending
- 2018-05-10 JP JP2019562415A patent/JP7146286B2/ja active Active
-
2022
- 2022-08-18 US US17/820,815 patent/US20220390448A1/en active Pending
- 2022-08-18 US US17/820,803 patent/US12174187B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013528799A (ja) | 2010-05-13 | 2013-07-11 | ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 神経変性疾患の検知および診断のための診断用自己抗体プロファイル |
Non-Patent Citations (1)
| Title |
|---|
| Antigen Microarrays Identify Unique Serum Autoantibody Signatures in Clinical and Pathologic Subtypes of Multiple Sclerosis,Proceedings of the National Academy of Sciences of the United States of America,2008年,Vol.105, No.48,pp.18889-18894,DOI: 10.1073/pnas.0806310105 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20220390447A1 (en) | 2022-12-08 |
| CA3062763A1 (en) | 2018-11-15 |
| US12174187B2 (en) | 2024-12-24 |
| US20210003570A1 (en) | 2021-01-07 |
| US20220390448A1 (en) | 2022-12-08 |
| EP3622291A1 (en) | 2020-03-18 |
| JP2020519895A (ja) | 2020-07-02 |
| WO2018209126A1 (en) | 2018-11-15 |
| EP3622291A4 (en) | 2021-04-21 |
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