JP7132911B2 - リポソームアンチセンスオリゴヌクレオチドとの併用療法 - Google Patents

リポソームアンチセンスオリゴヌクレオチドとの併用療法 Download PDF

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JP7132911B2
JP7132911B2 JP2019514777A JP2019514777A JP7132911B2 JP 7132911 B2 JP7132911 B2 JP 7132911B2 JP 2019514777 A JP2019514777 A JP 2019514777A JP 2019514777 A JP2019514777 A JP 2019514777A JP 7132911 B2 JP7132911 B2 JP 7132911B2
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cancer
pharmaceutical composition
grb2
combination
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アナ タリ アシザワ，
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バイオ－パス ホールディングス， インコーポレイテッド
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
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JP2019514777A 2016-09-16 2017-09-15 リポソームアンチセンスオリゴヌクレオチドとの併用療法 Active JP7132911B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662395680P 2016-09-16 2016-09-16
US62/395,680 2016-09-16
US201762487277P 2017-04-19 2017-04-19
US62/487,277 2017-04-19
PCT/US2017/051723 WO2018053232A1 (en) 2016-09-16 2017-09-15 Combination therapy with liposomal antisense oligonucleotides

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JP2019529420A JP2019529420A (ja) 2019-10-17
JP2019529420A5 JP2019529420A5 (enExample) 2020-09-24
JP7132911B2 true JP7132911B2 (ja) 2022-09-07

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US (2) US10927379B2 (enExample)
EP (1) EP3512525B1 (enExample)
JP (1) JP7132911B2 (enExample)
KR (1) KR20190053905A (enExample)
CN (1) CN109963571A (enExample)
AU (2) AU2017325971A1 (enExample)
BR (1) BR112019005166A2 (enExample)
CA (1) CA3034637A1 (enExample)
ES (1) ES2928654T3 (enExample)
MX (1) MX2019003070A (enExample)
SG (2) SG11201901667TA (enExample)
WO (1) WO2018053232A1 (enExample)
ZA (1) ZA201902079B (enExample)

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KR102755601B1 (ko) 2015-10-14 2025-01-17 바이오-패쓰 홀딩스 인크. 리포좀 제제를 위한 p-에톡시 핵산
US10927379B2 (en) 2016-09-16 2021-02-23 Bio-Path Holdings, Inc. Combination therapy with liposomal antisense oligonucleotides
IL269608B2 (en) 2017-04-19 2024-06-01 Bio Path Holdings Inc Compositions comprising p-ethoxy nucleic acids for stat3 inhibition for use in treating cancer or autoimmune disease
US12234457B2 (en) * 2017-04-19 2025-02-25 Bio-Path Holdings, Inc. P-ethoxy nucleic acids for BCL2 inhibition
EP4213948A4 (en) * 2020-09-16 2024-12-25 Board of Regents, The University of Texas System Methods for treating cancers with inhibitors targeting the role of grb2 in dna repair
CN112891376B (zh) * 2021-03-09 2023-02-03 阜阳天祥食品科技有限公司 羊油在制备治疗肺癌药品中的应用

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