JP7109092B2 - リドカインおよびジクロフェナクを含む神経障害性疼痛の治療用の医薬用貼付剤 - Google Patents

リドカインおよびジクロフェナクを含む神経障害性疼痛の治療用の医薬用貼付剤 Download PDF

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JP7109092B2
JP7109092B2 JP2019541220A JP2019541220A JP7109092B2 JP 7109092 B2 JP7109092 B2 JP 7109092B2 JP 2019541220 A JP2019541220 A JP 2019541220A JP 2019541220 A JP2019541220 A JP 2019541220A JP 7109092 B2 JP7109092 B2 JP 7109092B2
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pain
lidocaine
diclofenac
skin
component
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JP2020505416A5 (enExample
JP2020505416A (ja
Inventor
アントニオ・ナルディ
クラウス・シーネ
トーマス・クリストフ
ゼバスティアン・ヴァハテン
イルムガルト・ベスル
アンドレアス・ショルツ
インゴ・フリードリヒ
ゼバスティアン・ウルリヒ
ジモーネ・ケーニヒ
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Teikoku Seiyaku Co Ltd
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Teikoku Seiyaku Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2019541220A 2017-01-31 2018-01-29 リドカインおよびジクロフェナクを含む神経障害性疼痛の治療用の医薬用貼付剤 Active JP7109092B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17154009 2017-01-31
EP17154009.9 2017-01-31
PCT/EP2018/052031 WO2018141661A1 (en) 2017-01-31 2018-01-29 Pharmaceutical patch comprising lidocaine and diclofenac for treating neuropathic pain

Publications (3)

Publication Number Publication Date
JP2020505416A JP2020505416A (ja) 2020-02-20
JP2020505416A5 JP2020505416A5 (enExample) 2021-03-11
JP7109092B2 true JP7109092B2 (ja) 2022-07-29

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JP2019541220A Active JP7109092B2 (ja) 2017-01-31 2018-01-29 リドカインおよびジクロフェナクを含む神経障害性疼痛の治療用の医薬用貼付剤

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Country Link
US (1) US20190388360A1 (enExample)
JP (1) JP7109092B2 (enExample)
WO (1) WO2018141661A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2893527T3 (es) 2016-12-28 2022-02-09 Hisamitsu Pharmaceutical Co Parche
MX2022005168A (es) * 2019-11-06 2022-06-08 Smartech Topical Inc Formulaciones topicas de inhibidores de la ciclooxigenasa y su uso.
JP6744511B1 (ja) * 2020-02-12 2020-08-19 久光製薬株式会社 ジクロフェナクナトリウム含有貼付剤
JP2023551417A (ja) * 2020-11-20 2023-12-08 セーリング ファーマシューティカル テクノロジー グループ カンパニー リミテッド ブルシンゲルプラスター、その製造方法および使用
US11872320B2 (en) 2021-02-25 2024-01-16 Hisamitsu Pharmaceutical Co., Inc. Method for treating osteoarthritis

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001047559A1 (fr) 1999-12-27 2001-07-05 Teikoku Seiyaku Co., Ltd Pastilles a usage externe
JP2004323502A (ja) 2002-08-02 2004-11-18 Medorekkusu:Kk 浸透拡散性に優れた消炎鎮痛外用剤
JP2005068035A (ja) 2003-08-20 2005-03-17 Medorekkusu:Kk 慢性疼痛治療用外用剤
JP2005145930A (ja) 2003-11-19 2005-06-09 Medorekkusu:Kk 非ステロイド系消炎鎮痛剤を含む消炎鎮痛外用剤および組成物の製造方法
JP2005145931A (ja) 2003-11-19 2005-06-09 Medorekkusu:Kk 非ステロイド系消炎鎮痛剤を含有するテープ剤
CN101530401A (zh) 2008-03-12 2009-09-16 中山市中健药物研究所有限公司 一种用于治疗急慢性炎性疼痛的复方透皮贴片
JP2013501051A (ja) 2009-08-06 2013-01-10 株式会社エービーサイズ ナノ粒子の溶液およびナノ粒子の懸濁物の両者を有する局所用薬学的調製物ならびに該調製物をもって急性疼痛および慢性疼痛を処置する方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7166641B2 (en) 2002-10-02 2007-01-23 Yung Shin Pharmaceutical Industrial Co., Ltd. Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same
DE102004001093A1 (de) 2004-01-05 2005-07-28 Liedtke, Rainer K., Dr. Zusammensetzung und Methode einer synergistischen topischen Therapie neuromuskulärer Schmerzen
WO2011005853A2 (en) 2009-07-08 2011-01-13 Msk Pharma, Llc Compositions and methods of topical drug delivery for the treatment of carpal tunnel syndrome

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001047559A1 (fr) 1999-12-27 2001-07-05 Teikoku Seiyaku Co., Ltd Pastilles a usage externe
JP2004323502A (ja) 2002-08-02 2004-11-18 Medorekkusu:Kk 浸透拡散性に優れた消炎鎮痛外用剤
JP2005068035A (ja) 2003-08-20 2005-03-17 Medorekkusu:Kk 慢性疼痛治療用外用剤
JP2005145930A (ja) 2003-11-19 2005-06-09 Medorekkusu:Kk 非ステロイド系消炎鎮痛剤を含む消炎鎮痛外用剤および組成物の製造方法
JP2005145931A (ja) 2003-11-19 2005-06-09 Medorekkusu:Kk 非ステロイド系消炎鎮痛剤を含有するテープ剤
CN101530401A (zh) 2008-03-12 2009-09-16 中山市中健药物研究所有限公司 一种用于治疗急慢性炎性疼痛的复方透皮贴片
JP2013501051A (ja) 2009-08-06 2013-01-10 株式会社エービーサイズ ナノ粒子の溶液およびナノ粒子の懸濁物の両者を有する局所用薬学的調製物ならびに該調製物をもって急性疼痛および慢性疼痛を処置する方法

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WO2018141661A1 (en) 2018-08-09
US20190388360A1 (en) 2019-12-26
JP2020505416A (ja) 2020-02-20

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