JP7093728B2 - 化学的に修飾されたガイドｒｎａを使用する高特異性ゲノム編集 - Google Patents

化学的に修飾されたガイドｒｎａを使用する高特異性ゲノム編集 Download PDF

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JP7093728B2
JP7093728B2 JP2018564259A JP2018564259A JP7093728B2 JP 7093728 B2 JP7093728 B2 JP 7093728B2 JP 2018564259 A JP2018564259 A JP 2018564259A JP 2018564259 A JP2018564259 A JP 2018564259A JP 7093728 B2 JP7093728 B2 JP 7093728B2
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certain embodiments
sequence
guide
nucleotides
modification
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JP2019517268A (ja
JP2019517268A5 (https=
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デリンジャー，ダグラス・ジェイ
ライアン，ダニエル・イー
スバディープ，ロイ
サンプソン，ジェフリー・アール
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Agilent Technologies Inc
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JP2018564259A 2016-06-08 2017-06-08 化学的に修飾されたガイドｒｎａを使用する高特異性ゲノム編集 Active JP7093728B2 (ja)

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US201662347553P 2016-06-08 2016-06-08
US62/347,553 2016-06-08
US15/493,129 2017-04-20
US15/493,129 US10767175B2 (en) 2016-06-08 2017-04-20 High specificity genome editing using chemically modified guide RNAs
PCT/US2017/036648 WO2017214460A1 (en) 2016-06-08 2017-06-08 High specificity genome editing using chemically modified guide rnas

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JP2022098789A Active JP7431891B2 (ja) 2016-06-08 2022-06-20 化学的に修飾されたガイドｒｎａを使用する高特異性ゲノム編集

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US (2) US10767175B2 (https=)
EP (1) EP3469084A4 (https=)
JP (2) JP7093728B2 (https=)
KR (1) KR102382772B1 (https=)
CN (2) CN116676305A (https=)
AU (1) AU2017277918B2 (https=)
WO (1) WO2017214460A1 (https=)

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