JP7091244B2 - デオキシシチジンキナーゼ結合化合物 - Google Patents

デオキシシチジンキナーゼ結合化合物 Download PDF

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JP7091244B2
JP7091244B2 JP2018535341A JP2018535341A JP7091244B2 JP 7091244 B2 JP7091244 B2 JP 7091244B2 JP 2018535341 A JP2018535341 A JP 2018535341A JP 2018535341 A JP2018535341 A JP 2018535341A JP 7091244 B2 JP7091244 B2 JP 7091244B2
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JP2019504833A5 (enExample
JP2019504833A (ja
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ラドゥ，カイウス・ジー
ギプソン，レイモンド・エム
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ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2018535341A 2016-01-08 2017-01-09 デオキシシチジンキナーゼ結合化合物 Active JP7091244B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662276546P 2016-01-08 2016-01-08
US62/276,546 2016-01-08
PCT/US2017/012718 WO2017120585A1 (en) 2016-01-08 2017-01-09 Deoxycytidine kinase binding compounds

Publications (3)

Publication Number Publication Date
JP2019504833A JP2019504833A (ja) 2019-02-21
JP2019504833A5 JP2019504833A5 (enExample) 2020-02-20
JP7091244B2 true JP7091244B2 (ja) 2022-06-27

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JP2018535341A Active JP7091244B2 (ja) 2016-01-08 2017-01-09 デオキシシチジンキナーゼ結合化合物

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US (1) US10570124B2 (enExample)
EP (1) EP3400224A4 (enExample)
JP (1) JP7091244B2 (enExample)
CN (1) CN108779111B (enExample)
AU (1) AU2017205336A1 (enExample)
CA (1) CA3010723A1 (enExample)
WO (1) WO2017120585A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3230259B1 (en) 2014-12-08 2024-04-03 The Research Foundation for The State University of New York Anti-fungals targeting the synthesis of fungal shingolipids
US11414378B2 (en) 2017-06-16 2022-08-16 The Research Foundation For The State University Of New York Anti-fungals compounds targeting the synthesis of fungal sphingolipids
CN116723845A (zh) * 2020-11-02 2023-09-08 特雷西拉公司 脱氧胞苷激酶抑制剂的结晶形式及其用途
JP2023548605A (ja) * 2020-11-02 2023-11-17 トレセラ コーポレーション デオキシシチジンキナーゼ阻害剤の結晶形態およびその使用
US20250092032A1 (en) * 2022-01-17 2025-03-20 Centre National De La Recherche Scientifique Deoxycytidine kinase inhibitors
WO2024186827A2 (en) * 2023-03-06 2024-09-12 The Regents Of The University Of California Novel host-directed therapeutic agent for the treatment of infectious diseases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012122368A1 (en) 2011-03-08 2012-09-13 The Regents Of The University Of California Deoxycytidine kinase binding compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2529293T3 (es) 2007-09-19 2015-02-18 The Regents Of The University Of California Sondas para tomografía de emisión de positrones para generación de imágenes de activación inmune y cánceres seleccionados
WO2015023776A2 (en) * 2013-08-13 2015-02-19 The Regents Of The University Of California Deoxycytidine kinase inhibitors
JP2018510134A (ja) * 2015-02-09 2018-04-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 組合せがん治療法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012122368A1 (en) 2011-03-08 2012-09-13 The Regents Of The University Of California Deoxycytidine kinase binding compounds

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Publication number Publication date
EP3400224A4 (en) 2019-08-07
CA3010723A1 (en) 2017-07-13
JP2019504833A (ja) 2019-02-21
EP3400224A1 (en) 2018-11-14
US10570124B2 (en) 2020-02-25
CN108779111A (zh) 2018-11-09
US20190016714A1 (en) 2019-01-17
AU2017205336A1 (en) 2018-07-26
CN108779111B (zh) 2021-11-12
WO2017120585A1 (en) 2017-07-13

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