CA3010723A1 - Deoxycytidine kinase binding compounds - Google Patents

Deoxycytidine kinase binding compounds Download PDF

Info

Publication number
CA3010723A1
CA3010723A1 CA3010723A CA3010723A CA3010723A1 CA 3010723 A1 CA3010723 A1 CA 3010723A1 CA 3010723 A CA3010723 A CA 3010723A CA 3010723 A CA3010723 A CA 3010723A CA 3010723 A1 CA3010723 A1 CA 3010723A1
Authority
CA
Canada
Prior art keywords
compound
optionally substituted
substituted
formula
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3010723A
Other languages
English (en)
French (fr)
Inventor
Caius G. Radu
Raymond M. GIPSON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of CA3010723A1 publication Critical patent/CA3010723A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA3010723A 2016-01-08 2017-01-09 Deoxycytidine kinase binding compounds Abandoned CA3010723A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662276546P 2016-01-08 2016-01-08
US62/276,546 2016-01-08
PCT/US2017/012718 WO2017120585A1 (en) 2016-01-08 2017-01-09 Deoxycytidine kinase binding compounds

Publications (1)

Publication Number Publication Date
CA3010723A1 true CA3010723A1 (en) 2017-07-13

Family

ID=59274442

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3010723A Abandoned CA3010723A1 (en) 2016-01-08 2017-01-09 Deoxycytidine kinase binding compounds

Country Status (7)

Country Link
US (1) US10570124B2 (enExample)
EP (1) EP3400224A4 (enExample)
JP (1) JP7091244B2 (enExample)
CN (1) CN108779111B (enExample)
AU (1) AU2017205336A1 (enExample)
CA (1) CA3010723A1 (enExample)
WO (1) WO2017120585A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3230259B1 (en) 2014-12-08 2024-04-03 The Research Foundation for The State University of New York Anti-fungals targeting the synthesis of fungal shingolipids
US11414378B2 (en) 2017-06-16 2022-08-16 The Research Foundation For The State University Of New York Anti-fungals compounds targeting the synthesis of fungal sphingolipids
CN116723845A (zh) * 2020-11-02 2023-09-08 特雷西拉公司 脱氧胞苷激酶抑制剂的结晶形式及其用途
JP2023548605A (ja) * 2020-11-02 2023-11-17 トレセラ コーポレーション デオキシシチジンキナーゼ阻害剤の結晶形態およびその使用
US20250092032A1 (en) * 2022-01-17 2025-03-20 Centre National De La Recherche Scientifique Deoxycytidine kinase inhibitors
WO2024186827A2 (en) * 2023-03-06 2024-09-12 The Regents Of The University Of California Novel host-directed therapeutic agent for the treatment of infectious diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2529293T3 (es) 2007-09-19 2015-02-18 The Regents Of The University Of California Sondas para tomografía de emisión de positrones para generación de imágenes de activación inmune y cánceres seleccionados
WO2012122368A1 (en) 2011-03-08 2012-09-13 The Regents Of The University Of California Deoxycytidine kinase binding compounds
WO2015023776A2 (en) * 2013-08-13 2015-02-19 The Regents Of The University Of California Deoxycytidine kinase inhibitors
JP2018510134A (ja) * 2015-02-09 2018-04-12 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 組合せがん治療法

Also Published As

Publication number Publication date
EP3400224A4 (en) 2019-08-07
JP2019504833A (ja) 2019-02-21
EP3400224A1 (en) 2018-11-14
US10570124B2 (en) 2020-02-25
CN108779111A (zh) 2018-11-09
US20190016714A1 (en) 2019-01-17
AU2017205336A1 (en) 2018-07-26
JP7091244B2 (ja) 2022-06-27
CN108779111B (zh) 2021-11-12
WO2017120585A1 (en) 2017-07-13

Similar Documents

Publication Publication Date Title
US11964941B2 (en) 5-Bromo-indirubins
US10570124B2 (en) Deoxycytidine kinase binding compounds
US11306072B2 (en) 5-bromo-indirubins
EP3941905A1 (en) Sumo inhibitor compounds and uses thereof
US11840523B2 (en) IRE1α inhibitors and uses thereof
US20250049808A1 (en) Crystalline forms of a deoxycytidine kinase inhibitor and uses thereof
US20230127630A1 (en) Igf2bp2 inhibitors and uses thereof
US20230114304A1 (en) Depalmitoylating compositions and the use thereof
CN116723845A (zh) 脱氧胞苷激酶抑制剂的结晶形式及其用途
WO2022055940A1 (en) Vista inhibitors
EP4153575A1 (en) Notch inhibitors and uses thereof
HK1220197B (en) 5-bromo-indirubins

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20230331

FZDE Discontinued

Effective date: 20230331