JP7075136B2 - 整形外科疾患の治療のための組成物および方法 - Google Patents

整形外科疾患の治療のための組成物および方法 Download PDF

Info

Publication number
JP7075136B2
JP7075136B2 JP2019538564A JP2019538564A JP7075136B2 JP 7075136 B2 JP7075136 B2 JP 7075136B2 JP 2019538564 A JP2019538564 A JP 2019538564A JP 2019538564 A JP2019538564 A JP 2019538564A JP 7075136 B2 JP7075136 B2 JP 7075136B2
Authority
JP
Japan
Prior art keywords
ginger
composition
fracture
citrulline
dietary supplement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019538564A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019529569A (ja
JP2019529569A5 (OSRAM
Inventor
ラジファー,ヤコブ
ラジファー,レベッカ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
K L R M LLC
Original Assignee
K L R M LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by K L R M LLC filed Critical K L R M LLC
Publication of JP2019529569A publication Critical patent/JP2019529569A/ja
Publication of JP2019529569A5 publication Critical patent/JP2019529569A5/ja
Application granted granted Critical
Publication of JP7075136B2 publication Critical patent/JP7075136B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2019538564A 2016-09-29 2017-09-29 整形外科疾患の治療のための組成物および方法 Active JP7075136B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662401629P 2016-09-29 2016-09-29
US62/401,629 2016-09-29
US201762511601P 2017-05-26 2017-05-26
US62/511,601 2017-05-26
PCT/US2017/054284 WO2018064469A1 (en) 2016-09-29 2017-09-29 Compositions and methods for the treatment of orthopedic ailments

Publications (3)

Publication Number Publication Date
JP2019529569A JP2019529569A (ja) 2019-10-17
JP2019529569A5 JP2019529569A5 (OSRAM) 2020-07-27
JP7075136B2 true JP7075136B2 (ja) 2022-05-25

Family

ID=61760145

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019538564A Active JP7075136B2 (ja) 2016-09-29 2017-09-29 整形外科疾患の治療のための組成物および方法

Country Status (9)

Country Link
US (3) US10426812B2 (OSRAM)
EP (1) EP3518951B1 (OSRAM)
JP (1) JP7075136B2 (OSRAM)
KR (1) KR102491748B1 (OSRAM)
CN (1) CN110087664B (OSRAM)
AU (1) AU2017336916A1 (OSRAM)
ES (1) ES2971281T3 (OSRAM)
IL (1) IL265571B (OSRAM)
WO (1) WO2018064469A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102491748B1 (ko) * 2016-09-29 2023-01-25 케이.엘.알.엠., 엘엘씨 정형외과적 질병의 치료를 위한 조성물 및 방법
CN113543649A (zh) * 2019-02-06 2021-10-22 K.L.R.M.有限公司 治疗便秘和其他胃肠系统疾病的组合物和方法
CN112791171A (zh) * 2019-11-13 2021-05-14 内蒙古伊利实业集团股份有限公司 姜或其提取物用于防治骨质疏松的用途
CN119818501A (zh) * 2025-01-14 2025-04-15 北京大学口腔医学院 西地那非的新用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016141331A1 (en) 2015-03-04 2016-09-09 K.L.R.M., Llc Methods and compositions for extending the efficacy of phosphodiesterase inhibitors for treating erectile dysfunction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000191542A (ja) * 1998-12-25 2000-07-11 Lion Corp 骨粗鬆症予防、治療剤
US6210701B1 (en) 1999-04-30 2001-04-03 Healthcomm International, Inc. Medical food for treating inflammation-related diseases
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
US20040097467A1 (en) * 2002-08-22 2004-05-20 Vijaya Juturu Arginine silicate inositol complex and use thereof
US20070243132A1 (en) * 2005-12-22 2007-10-18 Apollo Life Sciences Limited Transdermal delivery of pharmaceutical agents
US20120121740A1 (en) * 2010-10-19 2012-05-17 K.L.R.M., Llc Compositions and methods for treating, inhibiting the onset, and slowing the progression of erectile dysfunction including naturally occurring age related erectile dysfunction
US20120093950A1 (en) * 2010-10-19 2012-04-19 Klrm, Llc Compositions and methods for treating, inhibiting the onset, and slowing the progression of erectile dysfunction including naturally occuring age related erectile dysfunction
KR102491748B1 (ko) * 2016-09-29 2023-01-25 케이.엘.알.엠., 엘엘씨 정형외과적 질병의 치료를 위한 조성물 및 방법

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016141331A1 (en) 2015-03-04 2016-09-09 K.L.R.M., Llc Methods and compositions for extending the efficacy of phosphodiesterase inhibitors for treating erectile dysfunction

Also Published As

Publication number Publication date
US20180104300A1 (en) 2018-04-19
KR102491748B1 (ko) 2023-01-25
ES2971281T3 (es) 2024-06-04
EP3518951A1 (en) 2019-08-07
CN110087664B (zh) 2022-11-01
KR20190061045A (ko) 2019-06-04
CN110087664A (zh) 2019-08-02
JP2019529569A (ja) 2019-10-17
AU2017336916A1 (en) 2019-04-18
US10792324B2 (en) 2020-10-06
US10426812B2 (en) 2019-10-01
US20200215146A1 (en) 2020-07-09
EP3518951A4 (en) 2020-05-27
EP3518951C0 (en) 2024-01-10
IL265571A (en) 2019-05-30
EP3518951B1 (en) 2024-01-10
US20190381124A1 (en) 2019-12-19
IL265571B (en) 2022-03-01
WO2018064469A1 (en) 2018-04-05

Similar Documents

Publication Publication Date Title
US10792324B2 (en) Compositions and methods for the treatment of orthopedic ailments
JP2022037132A (ja) 筋萎縮性側索硬化症患者の下位集団の治療のためのマシチニブの使用
JP2016507553A (ja) 骨成長を促進する非晶質炭酸カルシウム
Aydoğan et al. The effect of vitamin D and bisphosphonate on fracture healing: An experimental study
US9827273B2 (en) Preparation and method for the prophylaxis and treatment of atypical osteoporosis
Rajfer et al. Enhancement of fracture healing in the rat, modulated by compounds that stimulate inducible nitric oxide synthase: acceleration of fracture healing via inducible nitric oxide synthase
WO2011091247A1 (en) Mixed aminal pharmaceutical compositions and uses thereof
US9056105B2 (en) Method for treatment of bone diseases and fractures
O'Loughlin et al. IRON NOF trial: IV iron for anaemic patients with femoral fracture
BR112017007364B1 (pt) Composições farmacêuticas e usos das mesmas para o tratamento ou prevenção de deficiências de vitaminas e minerais em pacientes submetidos à cirurgia de bypass gástrico
US20250213644A1 (en) Compositions and methods for treatment of bone-related disease or disorder
HK40010195B (en) Compositions and methods for the treatment of orthopedic ailments
HK40010195A (en) Compositions and methods for the treatment of orthopedic ailments
Gupta et al. Retrograde titanium elastic nailing in management of length unstable pediatric femoral shaft fracture
Tatara et al. 7. Novel and current approaches to dietary and non-dietary bone metabolism regulation
Yousefi-Manesh et al. The therapeutic effect of Astaxanthin on drill-induced closed femoral fracture model in male Wistar rats
RU2778611C1 (ru) Способ комплексного лечения дегенеративно-дистрофических заболеваний опорно-двигательного аппарата
Krohn Systemic Agents in Fracture Healing
Lalić et al. Definite management of bilateral lower leg nonunion fractures by Ilizarov apparatus in polytraumatized patient: Case report
Aburawi et al. Effect of black tea preparation on vitamin C absorption in albino rat ileum using everted gut sac technique
Kilinc et al. Hemiarthroplasty with cementless intramedullary stem versus proximal femoral nail in the treatment of unstable intertrochanteric fractures in elderly patients
CN105101980B (zh) 用于加快骨折愈合的方法和组合物
CN114366807A (zh) 一种用于预防和/或治疗骨关节炎的组合物
KR20220064039A (ko) 척수 손상 예방 또는 치료용 조성물
Ballas Alendronic acid

Legal Events

Date Code Title Description
RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7426

Effective date: 20190708

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20190708

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200615

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20200615

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210615

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210914

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20211214

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220328

C60 Trial request (containing other claim documents, opposition documents)

Free format text: JAPANESE INTERMEDIATE CODE: C60

Effective date: 20220328

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20220405

C21 Notice of transfer of a case for reconsideration by examiners before appeal proceedings

Free format text: JAPANESE INTERMEDIATE CODE: C21

Effective date: 20220412

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20220426

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20220506

R150 Certificate of patent or registration of utility model

Ref document number: 7075136

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150