JP7046050B2 - フェニルマロン酸ジニトリルの調製方法 - Google Patents
フェニルマロン酸ジニトリルの調製方法 Download PDFInfo
- Publication number
- JP7046050B2 JP7046050B2 JP2019502626A JP2019502626A JP7046050B2 JP 7046050 B2 JP7046050 B2 JP 7046050B2 JP 2019502626 A JP2019502626 A JP 2019502626A JP 2019502626 A JP2019502626 A JP 2019502626A JP 7046050 B2 JP7046050 B2 JP 7046050B2
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- preparing
- malononitrile
- palladium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/33—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring with cyano groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/35—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/132—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
- C07C53/134—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings monocyclic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/44—Allylic alkylation, amination, alkoxylation or analogues
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/82—Metals of the platinum group
- B01J2531/824—Palladium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16180827.4 | 2016-07-22 | ||
| EP16180827 | 2016-07-22 | ||
| PCT/EP2017/068345 WO2018015489A1 (en) | 2016-07-22 | 2017-07-20 | Process for the preparation of phenylmalonic acid dinitriles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019521165A JP2019521165A (ja) | 2019-07-25 |
| JP2019521165A5 JP2019521165A5 (enExample) | 2020-08-27 |
| JP7046050B2 true JP7046050B2 (ja) | 2022-04-01 |
Family
ID=56507536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019502626A Active JP7046050B2 (ja) | 2016-07-22 | 2017-07-20 | フェニルマロン酸ジニトリルの調製方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10759742B2 (enExample) |
| EP (1) | EP3487837B1 (enExample) |
| JP (1) | JP7046050B2 (enExample) |
| CN (1) | CN109476588A (enExample) |
| BR (1) | BR112019000963B1 (enExample) |
| DK (1) | DK3487837T3 (enExample) |
| ES (1) | ES2928635T3 (enExample) |
| HU (1) | HUE060023T2 (enExample) |
| IL (1) | IL263688B (enExample) |
| MX (1) | MX2019000753A (enExample) |
| WO (1) | WO2018015489A1 (enExample) |
| ZA (1) | ZA201900032B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10759742B2 (en) * | 2016-07-22 | 2020-09-01 | Syngenta Participations Ag | Process for the preparation of phenylmalonic acid dinitriles |
| WO2018210616A1 (de) | 2017-05-15 | 2018-11-22 | Bayer Cropscience Aktiengesellschaft | Verfahren zur herstellung von (4-halogen-2,6-dialkylphenyl)malononitrilen |
| ES3042162T3 (en) | 2018-04-10 | 2025-11-18 | Bayer Ag | Method for the preparation of 2.6-dialkylphenyl acetic acids |
| CN109096146B (zh) * | 2018-09-03 | 2020-11-10 | 杭州中美华东制药有限公司 | 阿那曲唑关键中间体的合成方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003502403A (ja) | 1999-06-16 | 2003-01-21 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | 新規中間体 |
| JP2006509006A (ja) | 2002-12-05 | 2006-03-16 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | フェニルマロン酸ジニトリルの調製方法 |
| US20080318776A1 (en) | 2004-11-04 | 2008-12-25 | Reiner Fischer | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives |
| JP2012511541A (ja) | 2008-12-12 | 2012-05-24 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | 農薬としてのスピロ複素環式ｎ−オキシピペリジン |
| WO2015007640A1 (en) | 2013-07-19 | 2015-01-22 | Syngenta Participations Ag | Novel process for the preparation of spiroheterocyclic pyrrolidine diones |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP9802279A3 (en) | 1995-06-30 | 2001-05-28 | Bayer Ag | Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides |
| EP1062217B1 (en) * | 1998-03-13 | 2003-06-04 | Syngenta Participations AG | Herbicidally active 3-hydroxy-4-aryl-5-oxopyrazoline derivatives |
| WO2002070477A1 (en) * | 2001-03-01 | 2002-09-12 | Ono Pharmaceutical Co., Ltd. | 2-methylindole-4-acetic acid, process for producing the same, and process for producing intermediate therefor |
| CA2596590C (en) | 2005-02-09 | 2014-01-21 | Linhua Wang | Process for the preparation of intermediates |
| GB0720126D0 (en) | 2007-10-15 | 2007-11-28 | Syngenta Participations Ag | Chemical compounds |
| DK2406205T3 (en) | 2009-03-12 | 2017-02-27 | Bayer Ip Gmbh | PROCEDURE FOR MANUFACTURING CHLOR AND BROMAROMATS |
| US10759742B2 (en) * | 2016-07-22 | 2020-09-01 | Syngenta Participations Ag | Process for the preparation of phenylmalonic acid dinitriles |
-
2017
- 2017-07-20 US US16/319,304 patent/US10759742B2/en active Active
- 2017-07-20 ES ES17745158T patent/ES2928635T3/es active Active
- 2017-07-20 CN CN201780044592.9A patent/CN109476588A/zh active Pending
- 2017-07-20 WO PCT/EP2017/068345 patent/WO2018015489A1/en not_active Ceased
- 2017-07-20 EP EP17745158.0A patent/EP3487837B1/en active Active
- 2017-07-20 HU HUE17745158A patent/HUE060023T2/hu unknown
- 2017-07-20 BR BR112019000963-9A patent/BR112019000963B1/pt active IP Right Grant
- 2017-07-20 MX MX2019000753A patent/MX2019000753A/es unknown
- 2017-07-20 DK DK17745158.0T patent/DK3487837T3/da active
- 2017-07-20 JP JP2019502626A patent/JP7046050B2/ja active Active
-
2018
- 2018-12-13 IL IL263688A patent/IL263688B/en unknown
-
2019
- 2019-01-03 ZA ZA2019/00032A patent/ZA201900032B/en unknown
-
2020
- 2020-05-27 US US16/884,231 patent/US11136289B2/en active Active
-
2021
- 2021-06-03 US US17/337,615 patent/US20210284602A1/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003502403A (ja) | 1999-06-16 | 2003-01-21 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | 新規中間体 |
| JP2006509006A (ja) | 2002-12-05 | 2006-03-16 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | フェニルマロン酸ジニトリルの調製方法 |
| US20080318776A1 (en) | 2004-11-04 | 2008-12-25 | Reiner Fischer | 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives |
| JP2012511541A (ja) | 2008-12-12 | 2012-05-24 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | 農薬としてのスピロ複素環式ｎ−オキシピペリジン |
| WO2015007640A1 (en) | 2013-07-19 | 2015-01-22 | Syngenta Participations Ag | Novel process for the preparation of spiroheterocyclic pyrrolidine diones |
Non-Patent Citations (1)
| Title |
|---|
| Synlett，2006年，No.18，pp.3167-3169 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2928635T3 (es) | 2022-11-21 |
| EP3487837B1 (en) | 2022-08-17 |
| US20200283374A1 (en) | 2020-09-10 |
| IL263688A (en) | 2019-03-31 |
| EP3487837A1 (en) | 2019-05-29 |
| MX2019000753A (es) | 2019-06-03 |
| IL263688B (en) | 2022-02-01 |
| US11136289B2 (en) | 2021-10-05 |
| US10759742B2 (en) | 2020-09-01 |
| ZA201900032B (en) | 2019-09-25 |
| US20190263752A1 (en) | 2019-08-29 |
| BR112019000963B1 (pt) | 2022-07-12 |
| CN109476588A (zh) | 2019-03-15 |
| US20210284602A1 (en) | 2021-09-16 |
| BR112019000963A2 (pt) | 2019-04-30 |
| HUE060023T2 (hu) | 2023-01-28 |
| WO2018015489A1 (en) | 2018-01-25 |
| JP2019521165A (ja) | 2019-07-25 |
| DK3487837T3 (da) | 2022-10-31 |
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