JP7041618B6 - 蛍光較正スライド - Google Patents
蛍光較正スライド Download PDFInfo
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- JP7041618B6 JP7041618B6 JP2018524323A JP2018524323A JP7041618B6 JP 7041618 B6 JP7041618 B6 JP 7041618B6 JP 2018524323 A JP2018524323 A JP 2018524323A JP 2018524323 A JP2018524323 A JP 2018524323A JP 7041618 B6 JP7041618 B6 JP 7041618B6
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- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 13
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- 229910052782 aluminium Inorganic materials 0.000 description 7
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 7
- 238000003384 imaging method Methods 0.000 description 6
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- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 4
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- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
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- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
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- FWBHETKCLVMNFS-UHFFFAOYSA-N 4',6-Diamino-2-phenylindol Chemical compound C1=CC(C(=N)N)=CC=C1C1=CC2=CC=C(C(N)=N)C=C2N1 FWBHETKCLVMNFS-UHFFFAOYSA-N 0.000 description 1
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 229910020286 SiOxNy Inorganic materials 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 238000000339 bright-field microscopy Methods 0.000 description 1
- 229910019990 cerium-doped yttrium aluminum garnet Inorganic materials 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
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- 229910052801 chlorine Inorganic materials 0.000 description 1
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- 229910052802 copper Inorganic materials 0.000 description 1
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- 230000008021 deposition Effects 0.000 description 1
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- 239000003814 drug Substances 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
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- 229920005989 resin Polymers 0.000 description 1
- 229910052594 sapphire Inorganic materials 0.000 description 1
- 239000010980 sapphire Substances 0.000 description 1
- 229910019655 synthetic inorganic crystalline material Inorganic materials 0.000 description 1
- WGTODYJZXSJIAG-UHFFFAOYSA-N tetramethylrhodamine chloride Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=CC=C1C(O)=O WGTODYJZXSJIAG-UHFFFAOYSA-N 0.000 description 1
- JGVWCANSWKRBCS-UHFFFAOYSA-N tetramethylrhodamine thiocyanate Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=C(SC#N)C=C1C(O)=O JGVWCANSWKRBCS-UHFFFAOYSA-N 0.000 description 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Images
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
- G01N21/278—Constitution of standards
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6482—Sample cells, cuvettes
Landscapes
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022017825A JP2022066214A (ja) | 2015-12-23 | 2022-02-08 | 蛍光較正スライド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15202526 | 2015-12-23 | ||
| EP15202526.8 | 2015-12-23 | ||
| PCT/EP2016/082352 WO2017109057A1 (en) | 2015-12-23 | 2016-12-22 | Fluorescence calibration slide |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022017825A Division JP2022066214A (ja) | 2015-12-23 | 2022-02-08 | 蛍光較正スライド |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2019505824A JP2019505824A (ja) | 2019-02-28 |
| JP2019505824A5 JP2019505824A5 (enExample) | 2020-01-30 |
| JP7041618B2 JP7041618B2 (ja) | 2022-03-24 |
| JP7041618B6 true JP7041618B6 (ja) | 2022-05-31 |
Family
ID=55022391
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018524323A Active JP7041618B6 (ja) | 2015-12-23 | 2016-12-22 | 蛍光較正スライド |
| JP2022017825A Pending JP2022066214A (ja) | 2015-12-23 | 2022-02-08 | 蛍光較正スライド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022017825A Pending JP2022066214A (ja) | 2015-12-23 | 2022-02-08 | 蛍光較正スライド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11408821B2 (enExample) |
| EP (1) | EP3394657B1 (enExample) |
| JP (2) | JP7041618B6 (enExample) |
| CN (1) | CN108431664B (enExample) |
| RU (1) | RU2727554C2 (enExample) |
| WO (1) | WO2017109057A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7057279B6 (ja) * | 2015-12-23 | 2022-06-02 | コーニンクレッカ フィリップス エヌ ヴェ | デジタル病理学に関する較正スライド |
| TWI659227B (zh) | 2017-06-20 | 2019-05-11 | Academia Sinica | 以影像導引之顯微照射的顯微鏡系統及方法 |
| WO2020044762A1 (ja) | 2018-08-28 | 2020-03-05 | パナソニックＩｐマネジメント株式会社 | センサ基板及びその製造方法 |
| CA3112016A1 (en) * | 2018-09-10 | 2020-03-19 | Fluidigm Canada Inc. | Fused-reference particle based normalisation for imaging mass spectrometry |
| SG11202105311VA (en) * | 2018-11-29 | 2021-06-29 | Univ La Trobe | Method of identifying a structure |
| CN114651201A (zh) * | 2019-09-04 | 2022-06-21 | 耐克思乐生物科学有限责任公司 | 用于细胞计数测量的系统和方法 |
| CN110865058A (zh) * | 2019-11-21 | 2020-03-06 | 成都博奥独立医学实验室有限公司 | 激光微阵列芯片扫描仪的浓度梯度荧光校准片及校准方法 |
| DE102020201806A1 (de) | 2020-02-13 | 2021-08-19 | Carl Zeiss Microscopy Gmbh | Referenzprobe für ein Mikroskop und Verwendungen |
| CN111834244B (zh) * | 2020-07-24 | 2022-04-19 | 昆山国显光电有限公司 | 显示面板母板及制备方法 |
| WO2022047321A1 (en) * | 2020-08-31 | 2022-03-03 | Applied Materials, Inc. | Method of calibration of mfish using slides |
| TW202239968A (zh) * | 2020-12-21 | 2022-10-16 | 美商應用材料股份有限公司 | Merfish成像系統的標準化 |
| US20220283090A1 (en) * | 2021-03-04 | 2022-09-08 | Board Of Trustees Of The University Of Illinois | Optical phantom and method for characterizing optical imaging systems |
| US12204083B2 (en) * | 2021-03-30 | 2025-01-21 | Sigtuple Technologies Private Limited | Calibration slide for calibration of an automated microscope |
| US12259326B2 (en) * | 2021-10-20 | 2025-03-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Dry fluorescence calibration technique |
| WO2024054050A1 (ko) * | 2022-09-07 | 2024-03-14 | 주식회사 나노엔텍 | 세포 계수 장치의 품질관리용 슬라이드 및 이의 제조방법 |
| CN118275402B (zh) * | 2023-11-27 | 2025-10-17 | 比亚迪股份有限公司 | 荧光校准模板的确定方法及核酸检测仪的荧光校准方法 |
| EP4625042A1 (en) * | 2024-03-28 | 2025-10-01 | Université d'Aix Marseille | Direct metal nanoimprint |
| WO2025208070A1 (en) * | 2024-03-29 | 2025-10-02 | Syncell (Taiwan) Inc | Method of calibrating an image-guided microscopic illumination system |
| CN119223932B (zh) * | 2024-12-03 | 2025-02-14 | 北京林电伟业电子技术有限公司 | 一种荧光显微镜计量校准方法及系统 |
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| CN103353388A (zh) | 2013-05-15 | 2013-10-16 | 西安交通大学 | 一种具摄像功能的双目体式显微成像系统标定方法及装置 |
| JP2015102708A (ja) | 2013-11-26 | 2015-06-04 | 大日本印刷株式会社 | 顕微鏡画像校正用スライドガラス |
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| RU2018126775A (ru) | 2020-01-28 |
| RU2727554C2 (ru) | 2020-07-22 |
| JP7041618B2 (ja) | 2022-03-24 |
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| WO2017109057A1 (en) | 2017-06-29 |
| US11408821B2 (en) | 2022-08-09 |
| EP3394657A1 (en) | 2018-10-31 |
| EP3394657B1 (en) | 2022-08-24 |
| US20180292311A1 (en) | 2018-10-11 |
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| RU2018126775A3 (enExample) | 2020-03-24 |
| CN108431664B (zh) | 2021-11-02 |
| JP2019505824A (ja) | 2019-02-28 |
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