RU2727554C2 - Флуоресцентный калибровочный слайд - Google Patents
Флуоресцентный калибровочный слайд Download PDFInfo
- Publication number
- RU2727554C2 RU2727554C2 RU2018126775A RU2018126775A RU2727554C2 RU 2727554 C2 RU2727554 C2 RU 2727554C2 RU 2018126775 A RU2018126775 A RU 2018126775A RU 2018126775 A RU2018126775 A RU 2018126775A RU 2727554 C2 RU2727554 C2 RU 2727554C2
- Authority
- RU
- Russia
- Prior art keywords
- calibration
- fluorescence
- slide
- data
- fluorescence microscope
- Prior art date
Links
- 239000002086 nanomaterial Substances 0.000 claims abstract description 63
- 239000000758 substrate Substances 0.000 claims abstract description 54
- 229910052751 metal Inorganic materials 0.000 claims abstract description 44
- 239000002184 metal Substances 0.000 claims abstract description 44
- 230000005284 excitation Effects 0.000 claims abstract description 21
- 230000005855 radiation Effects 0.000 claims abstract description 20
- 230000031700 light absorption Effects 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 43
- 239000011325 microbead Substances 0.000 claims description 27
- 239000002356 single layer Substances 0.000 claims description 21
- 238000002073 fluorescence micrograph Methods 0.000 claims description 17
- 230000003287 optical effect Effects 0.000 claims description 17
- 238000012937 correction Methods 0.000 claims description 16
- 239000010410 layer Substances 0.000 claims description 10
- 229910052782 aluminium Inorganic materials 0.000 claims description 9
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 9
- 238000012545 processing Methods 0.000 claims description 9
- 239000003086 colorant Substances 0.000 claims description 8
- 238000005424 photoluminescence Methods 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 7
- 230000001575 pathological effect Effects 0.000 claims description 7
- 238000000151 deposition Methods 0.000 claims description 6
- 238000012360 testing method Methods 0.000 claims description 6
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 4
- 229910052737 gold Inorganic materials 0.000 claims description 4
- 239000010931 gold Substances 0.000 claims description 4
- 229910052709 silver Inorganic materials 0.000 claims description 4
- 239000004332 silver Substances 0.000 claims description 4
- 229910000838 Al alloy Inorganic materials 0.000 claims description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 239000010949 copper Substances 0.000 claims description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- 238000012795 verification Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 3
- 239000000126 substance Substances 0.000 abstract description 3
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000000737 periodic effect Effects 0.000 abstract 1
- 230000007170 pathology Effects 0.000 description 11
- 230000008569 process Effects 0.000 description 9
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 8
- 238000000799 fluorescence microscopy Methods 0.000 description 6
- 238000001459 lithography Methods 0.000 description 6
- 238000000206 photolithography Methods 0.000 description 6
- 239000000975 dye Substances 0.000 description 5
- 230000008021 deposition Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000006059 cover glass Substances 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 238000001312 dry etching Methods 0.000 description 3
- 239000007850 fluorescent dye Substances 0.000 description 3
- 238000001127 nanoimprint lithography Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 235000012239 silicon dioxide Nutrition 0.000 description 3
- 239000000377 silicon dioxide Substances 0.000 description 3
- 229910052581 Si3N4 Inorganic materials 0.000 description 2
- 229910004298 SiO 2 Inorganic materials 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000000862 absorption spectrum Methods 0.000 description 2
- 239000011324 bead Substances 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 238000000295 emission spectrum Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 238000007901 in situ hybridization Methods 0.000 description 2
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000037007 arousal Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000000339 bright-field microscopy Methods 0.000 description 1
- 229910019990 cerium-doped yttrium aluminum garnet Inorganic materials 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000004049 embossing Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000012632 fluorescent imaging Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000005350 fused silica glass Substances 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000001020 plasma etching Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229910052594 sapphire Inorganic materials 0.000 description 1
- 239000010980 sapphire Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229910019655 synthetic inorganic crystalline material Inorganic materials 0.000 description 1
- WGTODYJZXSJIAG-UHFFFAOYSA-N tetramethylrhodamine chloride Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=CC=C1C(O)=O WGTODYJZXSJIAG-UHFFFAOYSA-N 0.000 description 1
- JGVWCANSWKRBCS-UHFFFAOYSA-N tetramethylrhodamine thiocyanate Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=C(SC#N)C=C1C(O)=O JGVWCANSWKRBCS-UHFFFAOYSA-N 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
- G01N21/278—Constitution of standards
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6482—Sample cells, cuvettes
Landscapes
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15202526 | 2015-12-23 | ||
| EP15202526.8 | 2015-12-23 | ||
| PCT/EP2016/082352 WO2017109057A1 (en) | 2015-12-23 | 2016-12-22 | Fluorescence calibration slide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2018126775A RU2018126775A (ru) | 2020-01-28 |
| RU2018126775A3 RU2018126775A3 (enExample) | 2020-03-24 |
| RU2727554C2 true RU2727554C2 (ru) | 2020-07-22 |
Family
ID=55022391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018126775A RU2727554C2 (ru) | 2015-12-23 | 2016-12-22 | Флуоресцентный калибровочный слайд |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11408821B2 (enExample) |
| EP (1) | EP3394657B1 (enExample) |
| JP (2) | JP7041618B6 (enExample) |
| CN (1) | CN108431664B (enExample) |
| RU (1) | RU2727554C2 (enExample) |
| WO (1) | WO2017109057A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7057279B6 (ja) * | 2015-12-23 | 2022-06-02 | コーニンクレッカ フィリップス エヌ ヴェ | デジタル病理学に関する較正スライド |
| TWI659227B (zh) | 2017-06-20 | 2019-05-11 | Academia Sinica | 以影像導引之顯微照射的顯微鏡系統及方法 |
| WO2020044762A1 (ja) | 2018-08-28 | 2020-03-05 | パナソニックＩｐマネジメント株式会社 | センサ基板及びその製造方法 |
| CA3112016A1 (en) * | 2018-09-10 | 2020-03-19 | Fluidigm Canada Inc. | Fused-reference particle based normalisation for imaging mass spectrometry |
| SG11202105311VA (en) * | 2018-11-29 | 2021-06-29 | Univ La Trobe | Method of identifying a structure |
| CN114651201A (zh) * | 2019-09-04 | 2022-06-21 | 耐克思乐生物科学有限责任公司 | 用于细胞计数测量的系统和方法 |
| CN110865058A (zh) * | 2019-11-21 | 2020-03-06 | 成都博奥独立医学实验室有限公司 | 激光微阵列芯片扫描仪的浓度梯度荧光校准片及校准方法 |
| DE102020201806A1 (de) | 2020-02-13 | 2021-08-19 | Carl Zeiss Microscopy Gmbh | Referenzprobe für ein Mikroskop und Verwendungen |
| CN111834244B (zh) * | 2020-07-24 | 2022-04-19 | 昆山国显光电有限公司 | 显示面板母板及制备方法 |
| WO2022047321A1 (en) * | 2020-08-31 | 2022-03-03 | Applied Materials, Inc. | Method of calibration of mfish using slides |
| TW202239968A (zh) * | 2020-12-21 | 2022-10-16 | 美商應用材料股份有限公司 | Merfish成像系統的標準化 |
| US20220283090A1 (en) * | 2021-03-04 | 2022-09-08 | Board Of Trustees Of The University Of Illinois | Optical phantom and method for characterizing optical imaging systems |
| US12204083B2 (en) * | 2021-03-30 | 2025-01-21 | Sigtuple Technologies Private Limited | Calibration slide for calibration of an automated microscope |
| US12259326B2 (en) * | 2021-10-20 | 2025-03-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Dry fluorescence calibration technique |
| WO2024054050A1 (ko) * | 2022-09-07 | 2024-03-14 | 주식회사 나노엔텍 | 세포 계수 장치의 품질관리용 슬라이드 및 이의 제조방법 |
| CN118275402B (zh) * | 2023-11-27 | 2025-10-17 | 比亚迪股份有限公司 | 荧光校准模板的确定方法及核酸检测仪的荧光校准方法 |
| EP4625042A1 (en) * | 2024-03-28 | 2025-10-01 | Université d'Aix Marseille | Direct metal nanoimprint |
| WO2025208070A1 (en) * | 2024-03-29 | 2025-10-02 | Syncell (Taiwan) Inc | Method of calibrating an image-guided microscopic illumination system |
| CN119223932B (zh) * | 2024-12-03 | 2025-02-14 | 北京林电伟业电子技术有限公司 | 一种荧光显微镜计量校准方法及系统 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040196455A1 (en) * | 2001-03-28 | 2004-10-07 | Eugen Ermantraut | Device for referencing fluorescence signals |
| US20110318226A1 (en) * | 2004-07-16 | 2011-12-29 | Yu Ge | Calibration slide for fluorescence detection instruments and process of preparation |
| US20130109050A1 (en) * | 2009-05-07 | 2013-05-02 | Nodality, Inc. | Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19949029C2 (de) * | 1999-10-11 | 2002-11-21 | Innovatis Gmbh | Verfahren und Vorrichtung zur Charakterisierung einer Kulturflüssigkeit |
| JP4148340B2 (ja) * | 2001-08-31 | 2008-09-10 | 独立行政法人科学技術振興機構 | ナノサイズ構造体の製造方法及びその装置 |
| US6794424B2 (en) * | 2001-12-04 | 2004-09-21 | Agilent Technologies, Inc. | Devices for calibrating optical scanners and methods of using the same |
| TW561275B (en) * | 2002-05-13 | 2003-11-11 | Univ Nat Taiwan | Near-field super-resolution cover glass slip or mount |
| AU2003245499A1 (en) * | 2002-06-14 | 2003-12-31 | Chromavision Medical Systems, Inc. | Automated slide staining apparatus |
| JP4370900B2 (ja) | 2003-12-22 | 2009-11-25 | 横河電機株式会社 | バイオチップ基板保持方法およびバイオチップ読取装置 |
| JP2006275964A (ja) * | 2005-03-30 | 2006-10-12 | Olympus Corp | 走査型蛍光顕微鏡のシェーディング補正方法 |
| EP1949372A2 (en) * | 2005-11-11 | 2008-07-30 | Koninklijke Philips Electronics N.V. | System and method for positioning an information carrier in a scanning apparatus |
| US8192794B2 (en) * | 2006-04-19 | 2012-06-05 | Northwestern University | Massively parallel lithography with two-dimensional pen arrays |
| JP5244605B2 (ja) * | 2006-10-19 | 2013-07-24 | オリンパス株式会社 | 顕微鏡 |
| US10018818B2 (en) * | 2007-05-16 | 2018-07-10 | Photonanoscopy Corporation | Structured standing wave microscope |
| US7907271B2 (en) * | 2007-06-15 | 2011-03-15 | Historx, Inc. | Method and system for standardizing microscope instruments |
| US7955155B2 (en) | 2007-07-09 | 2011-06-07 | Mega Brands International | Magnetic and electronic toy construction systems and elements |
| CH708797B1 (de) * | 2007-08-17 | 2015-05-15 | Tecan Trading Ag | Probenteil-Magazin für eine Objektträger-Transportvorrichtung eines Laser Scanner-Geräts. |
| KR101605575B1 (ko) * | 2008-03-31 | 2016-03-22 | 키아겐 라케 콘스탄스 게엠베하 | 샘플 홀더 및 이를 이용하는 방법 |
| JP4561869B2 (ja) * | 2008-05-08 | 2010-10-13 | ソニー株式会社 | マイクロビーズ自動識別方法及びマイクロビーズ |
| JP5351551B2 (ja) * | 2009-02-20 | 2013-11-27 | パナソニック株式会社 | 発光装置 |
| JP2011099720A (ja) * | 2009-11-05 | 2011-05-19 | Hitachi High-Technologies Corp | 分析装置，オートフォーカス装置、及びオートフォーカス方法 |
| WO2011087894A1 (en) * | 2010-01-15 | 2011-07-21 | Qbc Diagnostics, Inc. | Fluorescent microscope slide |
| DE102010005860A1 (de) * | 2010-01-26 | 2011-07-28 | Christian-Albrechts-Universität zu Kiel, 24118 | Vorrichtung und Verfahren zur Kontrasterhöhung in der Mikroskopie |
| US8352207B2 (en) | 2010-03-31 | 2013-01-08 | Ecolab Usa Inc. | Methods for calibrating a fluorometer |
| DE102011003603B4 (de) * | 2011-02-03 | 2019-12-24 | Leica Microsystems (Schweiz) Ag | Durchlichtbeleuchtungseinrichtung für ein Mikroskop |
| EP2670812A2 (en) * | 2011-02-04 | 2013-12-11 | E.I. Du Pont De Nemours And Company | Azeotropic and azeotrope-like compositions involving certain haloolefins and uses thereof |
| CN102305776B (zh) * | 2011-05-26 | 2013-04-10 | 浙江大学 | 基于透明介质微球的超分辨显微成像系统 |
| US20130157261A1 (en) * | 2011-06-01 | 2013-06-20 | The Methodist Hospital Research Institute | Compositions and Methods for Quantitative Histology, Calibration of Images in Fluorescence Microscopy, and ddTUNEL Analyses |
| US20130044200A1 (en) * | 2011-08-17 | 2013-02-21 | Datacolor, Inc. | System and apparatus for the calibration and management of color in microscope slides |
| AU2012309205B2 (en) * | 2011-09-12 | 2015-05-14 | Agency For Science, Technology And Research | An optical arrangement and a method of forming the same |
| EP2653903A1 (en) * | 2012-04-20 | 2013-10-23 | FOM Institute for Atomic and Molecular Physics | Plasmonic microscopy |
| WO2013170366A2 (en) * | 2012-05-18 | 2013-11-21 | Huron Technologies International Inc. | Slide tray and receptor for microscopic slides and method of operation |
| EP4163617A1 (en) * | 2012-08-09 | 2023-04-12 | The Board of Trustees of the Leland Stanford Junior University | Methods and compositions for preparing biological specimens for microscopic analysis |
| DE102012214933B4 (de) * | 2012-08-22 | 2023-11-16 | Carl Zeiss Microscopy Gmbh | Testprobenvorrichtung und Testverfahren für ein optisches, im Sub-Wellenlängenbereich auflösendes Mikroskop |
| CN103353388B (zh) * | 2013-05-15 | 2016-04-06 | 西安交通大学 | 一种具摄像功能的双目体式显微成像系统标定方法及装置 |
| CN203405623U (zh) * | 2013-08-23 | 2014-01-22 | 马建军 | 一种新型内科显微镜检验片 |
| JP6187190B2 (ja) * | 2013-11-26 | 2017-08-30 | 大日本印刷株式会社 | 顕微鏡画像校正用スライドガラス |
| EP3087373B1 (en) * | 2013-12-24 | 2021-09-08 | King Abdullah University Of Science And Technology | Analytic device including nanostructures |
| JP2015190989A (ja) * | 2014-03-27 | 2015-11-02 | 横河電機株式会社 | パターン入りカバーガラス付きスライドガラス |
| US9797767B2 (en) * | 2014-08-26 | 2017-10-24 | General Electric Company | Calibration of microscopy systems |
| JP7057279B6 (ja) * | 2015-12-23 | 2022-06-02 | コーニンクレッカ フィリップス エヌ ヴェ | デジタル病理学に関する較正スライド |
-
2016
- 2016-12-22 CN CN201680075788.XA patent/CN108431664B/zh active Active
- 2016-12-22 WO PCT/EP2016/082352 patent/WO2017109057A1/en not_active Ceased
- 2016-12-22 JP JP2018524323A patent/JP7041618B6/ja active Active
- 2016-12-22 EP EP16822165.3A patent/EP3394657B1/en active Active
- 2016-12-22 RU RU2018126775A patent/RU2727554C2/ru active
-
2018
- 2018-06-15 US US16/009,285 patent/US11408821B2/en active Active
-
2022
- 2022-02-08 JP JP2022017825A patent/JP2022066214A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040196455A1 (en) * | 2001-03-28 | 2004-10-07 | Eugen Ermantraut | Device for referencing fluorescence signals |
| US20110318226A1 (en) * | 2004-07-16 | 2011-12-29 | Yu Ge | Calibration slide for fluorescence detection instruments and process of preparation |
| US20130109050A1 (en) * | 2009-05-07 | 2013-05-02 | Nodality, Inc. | Microbead kit and method for quantitative calibration and performance monitoring of a fluorescence instrument |
Non-Patent Citations (1)
| Title |
|---|
| Sarah Kim и др. "Patterned Arrays of Au Rings for Localized Surface Plasmon Resonance", LANGMUIR, т. 22, No 17, 2006 г., стр. 7109-7112. * |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2018126775A (ru) | 2020-01-28 |
| JP7041618B2 (ja) | 2022-03-24 |
| CN108431664A (zh) | 2018-08-21 |
| WO2017109057A1 (en) | 2017-06-29 |
| US11408821B2 (en) | 2022-08-09 |
| JP7041618B6 (ja) | 2022-05-31 |
| EP3394657A1 (en) | 2018-10-31 |
| EP3394657B1 (en) | 2022-08-24 |
| US20180292311A1 (en) | 2018-10-11 |
| JP2022066214A (ja) | 2022-04-28 |
| RU2018126775A3 (enExample) | 2020-03-24 |
| CN108431664B (zh) | 2021-11-02 |
| JP2019505824A (ja) | 2019-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2727554C2 (ru) | Флуоресцентный калибровочный слайд | |
| RU2734097C2 (ru) | Калибровочный слайд для цифровой патологии | |
| US8564792B2 (en) | Sub-diffraction limit image resolution in three dimensions | |
| US7961323B2 (en) | Microarray imaging system and associated methodology | |
| Jost et al. | Superresolution multidimensional imaging with structured illumination microscopy | |
| JP2019502942A5 (enExample) | ||
| JP2019505824A5 (enExample) | ||
| JP7693054B2 (ja) | 顕微鏡検査方法及びシステム | |
| US20110007386A1 (en) | Transmission microscopy using light emitted from nanoparticles | |
| KR20120020848A (ko) | 나노 구조 기반의 초고해상도 영상 방법 및 장치 | |
| US12196939B2 (en) | 3D target for optical system characterization | |
| KR101084018B1 (ko) | 국소 표면 플라즈몬 공명 기반의 초고해상도 전반사 형광 현미경 및 전반사 형광 현미경용 검출 모듈 | |
| CN111189807A (zh) | 基于波动的荧光显微术 | |
| CN108227233A (zh) | 基于光片结构光的显微层析超分辨率成像方法及系统 | |
| CN112513707A (zh) | 对象的描绘 | |
| van der Wee et al. | 3D test sample for the calibration and quality control of stimulated emission depletion (STED) and confocal microscopes | |
| Lam | Generation and Applications of “Collective Photonic Nanojets” | |
| Paul | Improving Sensitive Microscopy Techniques: SERS, SIM, and Spinning Disks | |
| Diaz | Review of the CH-STED performance and application range over conventional STED | |
| Fang et al. | Super-Resolution Radial Fluctuations (SRRF): A Versatile and Accessible Tool for Live-Cell Nanoscopy and Multimodal Imaging |