JP7027311B2 - ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療 - Google Patents

ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療 Download PDF

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JP7027311B2
JP7027311B2 JP2018524721A JP2018524721A JP7027311B2 JP 7027311 B2 JP7027311 B2 JP 7027311B2 JP 2018524721 A JP2018524721 A JP 2018524721A JP 2018524721 A JP2018524721 A JP 2018524721A JP 7027311 B2 JP7027311 B2 JP 7027311B2
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rna complex
asirna
rna
myd88
antisense strand
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リー，ドン－キ
ウー ホン，サン
ホン，イス
ヘ ファン，ジ
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オリックス ファーマシューティカルズ，インコーポレーテッド
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JP2018524721A 2015-11-16 2016-11-15 ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療 Active JP7027311B2 (ja)

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US201562255878P 2015-11-16 2015-11-16
US62/255,878 2015-11-16
PCT/IB2016/001745 WO2017085550A1 (en) 2015-11-16 2016-11-15 Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3

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JP2018533956A JP2018533956A (ja) 2018-11-22
JP2018533956A5 JP2018533956A5 (https=) 2019-12-26
JP7027311B2 true JP7027311B2 (ja) 2022-03-01

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US (2) US10059949B2 (https=)
EP (2) EP4454637A3 (https=)
JP (1) JP7027311B2 (https=)
KR (1) KR102727666B1 (https=)
CN (1) CN108699556B (https=)
CA (1) CA3005411C (https=)
WO (1) WO2017085550A1 (https=)

Families Citing this family (10)

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DK2631291T3 (da) 2010-10-22 2019-06-11 Olix Pharmaceuticals Inc Nukleinsyremolekyler, der inducerer rna-interferens, og anvendelser deraf
KR101567576B1 (ko) 2012-05-22 2015-11-10 올릭스 주식회사 세포 내 관통능을 가지고 ｒｎａ 간섭을 유도하는 핵산 분자 및 그 용도
JP7027311B2 (ja) 2015-11-16 2022-03-01 オリックス ファーマシューティカルズ，インコーポレーテッド ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療
JP6944942B2 (ja) 2016-02-02 2021-10-06 オリックス ファーマシューティカルズ，インコーポレーテッド ＩＬ４Ｒα、ＴＲＰＡ１、またはＦ２ＲＬ１を標的とするＲＮＡ複合体を用いたアトピー性皮膚炎および喘息の治療
CN108779464B (zh) 2016-02-02 2022-05-17 奥利克斯医药有限公司 使用靶向angpt2和pdgfb的rna复合物治疗血管生成相关性疾病
JP7049262B2 (ja) 2016-04-11 2022-04-06 オリックス ファーマシューティカルズ，インコーポレーテッド 結合組織成長因子を標的とするｒｎａ複合体を用いた特発性肺胞線維症の治療
KR101916652B1 (ko) 2016-06-29 2018-11-08 올릭스 주식회사 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
EP3580339A4 (en) 2017-02-10 2020-12-23 Research & Business Foundation Sungkyunkwan University LONG DOUBLE STRAND RNA FOR RNA INTERFERENCE
WO2021241802A1 (ko) * 2020-05-26 2021-12-02 올릭스 주식회사 연결 조직 성장 인자를 표적으로 하는 RNAi 제제 및 이의 용도
KR20240169190A (ko) * 2023-05-23 2024-12-03 주식회사 에스앤케이테라퓨틱스 자가면역 질환 치료를 위한 신규 MyD88 억제제 및 이의 용도

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