JP7027311B2 - ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療 - Google Patents

ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療 Download PDF

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JP7027311B2
JP7027311B2 JP2018524721A JP2018524721A JP7027311B2 JP 7027311 B2 JP7027311 B2 JP 7027311B2 JP 2018524721 A JP2018524721 A JP 2018524721A JP 2018524721 A JP2018524721 A JP 2018524721A JP 7027311 B2 JP7027311 B2 JP 7027311B2
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rna complex
asirna
rna
myd88
antisense strand
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リー，ドン－キ
ウー ホン，サン
ホン，イス
ヘ ファン，ジ
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オリックス ファーマシューティカルズ，インコーポレーテッド
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JP2018524721A 2015-11-16 2016-11-15 ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療 Active JP7027311B2 (ja)

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US201562255878P 2015-11-16 2015-11-16
US62/255,878 2015-11-16
PCT/IB2016/001745 WO2017085550A1 (en) 2015-11-16 2016-11-15 Treatment of age-related macular degeneration using rna complexes that target myd88 or tlr3

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JP2018533956A JP2018533956A (ja) 2018-11-22
JP2018533956A5 JP2018533956A5 (cg-RX-API-DMAC7.html) 2019-12-26
JP7027311B2 true JP7027311B2 (ja) 2022-03-01

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US (2) US10059949B2 (cg-RX-API-DMAC7.html)
EP (2) EP3377630A4 (cg-RX-API-DMAC7.html)
JP (1) JP7027311B2 (cg-RX-API-DMAC7.html)
KR (1) KR102727666B1 (cg-RX-API-DMAC7.html)
CN (1) CN108699556B (cg-RX-API-DMAC7.html)
CA (1) CA3005411C (cg-RX-API-DMAC7.html)
WO (1) WO2017085550A1 (cg-RX-API-DMAC7.html)

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JP5795072B2 (ja) 2010-10-22 2015-10-14 ソンギュングヮン ユニバーシティ ファウンデーション フォー コーポレート コラボレーション Ｒｎａ干渉を誘導する核酸分子及びその用途
JP6139671B2 (ja) 2012-05-22 2017-05-31 オリックス ファーマシューティカルズ インコーポレイテッドＯｌｉｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 細胞内貫通能を持ってｒｎａ干渉を誘導する核酸分子およびその用途
JP7027311B2 (ja) 2015-11-16 2022-03-01 オリックス ファーマシューティカルズ，インコーポレーテッド ＭｙＤ８８又はＴＬＲ３を標的とするＲＮＡ複合体を使用した加齢黄斑変性の治療
KR102825945B1 (ko) 2016-02-02 2025-06-30 올릭스 주식회사 Angpt2 및 pdgfb를 표적화하는 rna 복합체를 사용하는 혈관신생 관련 질환의 치료
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KR102339886B1 (ko) 2016-04-11 2021-12-17 올릭스 주식회사 연결 조직 성장 인자를 표적화하는 rna 복합체를 사용한 특발성 폐 섬유증의 치료 방법
KR101916652B1 (ko) 2016-06-29 2018-11-08 올릭스 주식회사 작은 간섭 rna의 rna 간섭효과 증진용 화합물 및 이의 용도
JP7424728B2 (ja) 2017-02-10 2024-01-30 オリック パルマセゥティカルズ インコーポレイテッド Ｒｎａ干渉のための長鎖の二本鎖ｒｎａ
CN115698287A (zh) * 2020-05-26 2023-02-03 奥利克斯医药有限公司 靶向MyD88的RNAi制剂以及其用途
KR20240169190A (ko) * 2023-05-23 2024-12-03 주식회사 에스앤케이테라퓨틱스 자가면역 질환 치료를 위한 신규 MyD88 억제제 및 이의 용도

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