JP6985233B2 - 針状突起を有する原版の製造方法、及びマイクロニードルアレイの製造方法 - Google Patents

針状突起を有する原版の製造方法、及びマイクロニードルアレイの製造方法 Download PDF

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Publication number
JP6985233B2
JP6985233B2 JP2018194095A JP2018194095A JP6985233B2 JP 6985233 B2 JP6985233 B2 JP 6985233B2 JP 2018194095 A JP2018194095 A JP 2018194095A JP 2018194095 A JP2018194095 A JP 2018194095A JP 6985233 B2 JP6985233 B2 JP 6985233B2
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Japan
Prior art keywords
needle
cutting tool
manufacturing
original plate
microneedle array
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JP2018194095A
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English (en)
Japanese (ja)
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JP2020062078A (ja
JP2020062078A5 (enExample
Inventor
リカルド イチロ オリ
博輝 柳川
梢 池田
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Fujifilm Corp
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Fujifilm Corp
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Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Priority to JP2018194095A priority Critical patent/JP6985233B2/ja
Priority to EP19200753.2A priority patent/EP3646919B1/en
Priority to US16/591,634 priority patent/US11597122B2/en
Priority to CN201910965740.1A priority patent/CN111035849B/zh
Publication of JP2020062078A publication Critical patent/JP2020062078A/ja
Publication of JP2020062078A5 publication Critical patent/JP2020062078A5/ja
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Publication of JP6985233B2 publication Critical patent/JP6985233B2/ja
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
    • B29C33/3842—Manufacturing moulds, e.g. shaping the mould surface by machining
    • B29C33/3857—Manufacturing moulds, e.g. shaping the mould surface by machining by making impressions of one or more parts of models, e.g. shaped articles and including possible subsequent assembly of the parts
    • B29C33/3892—Preparation of the model, e.g. by assembling parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B24—GRINDING; POLISHING
    • B24B—MACHINES, DEVICES, OR PROCESSES FOR GRINDING OR POLISHING; DRESSING OR CONDITIONING OF ABRADING SURFACES; FEEDING OF GRINDING, POLISHING, OR LAPPING AGENTS
    • B24B19/00—Single-purpose machines or devices for particular grinding operations not covered by any other main group
    • B24B19/16—Single-purpose machines or devices for particular grinding operations not covered by any other main group for grinding sharp-pointed workpieces, e.g. needles, pens, fish hooks, tweezers or record player styli
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
    • B29C33/3842—Manufacturing moulds, e.g. shaping the mould surface by machining
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/42—Moulds or cores; Details thereof or accessories therefor characterised by the shape of the moulding surface, e.g. ribs or grooves
    • B29C33/424—Moulding surfaces provided with means for marking or patterning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7544—Injection needles, syringes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/756—Microarticles, nanoarticles

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP2018194095A 2018-10-15 2018-10-15 針状突起を有する原版の製造方法、及びマイクロニードルアレイの製造方法 Active JP6985233B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2018194095A JP6985233B2 (ja) 2018-10-15 2018-10-15 針状突起を有する原版の製造方法、及びマイクロニードルアレイの製造方法
EP19200753.2A EP3646919B1 (en) 2018-10-15 2019-10-01 Manufacturing method of plate precursor having needle-like protrusion, and manufacturing method of microneedle array
US16/591,634 US11597122B2 (en) 2018-10-15 2019-10-03 Manufacturing method of plate precursor having needle-like protrusion, and manufacturing method of microneedle array
CN201910965740.1A CN111035849B (zh) 2018-10-15 2019-10-12 具有针状凸起的原版的制造方法及微针阵列的制造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2018194095A JP6985233B2 (ja) 2018-10-15 2018-10-15 針状突起を有する原版の製造方法、及びマイクロニードルアレイの製造方法

Publications (3)

Publication Number Publication Date
JP2020062078A JP2020062078A (ja) 2020-04-23
JP2020062078A5 JP2020062078A5 (enExample) 2021-02-25
JP6985233B2 true JP6985233B2 (ja) 2021-12-22

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JP2018194095A Active JP6985233B2 (ja) 2018-10-15 2018-10-15 針状突起を有する原版の製造方法、及びマイクロニードルアレイの製造方法

Country Status (4)

Country Link
US (1) US11597122B2 (enExample)
EP (1) EP3646919B1 (enExample)
JP (1) JP6985233B2 (enExample)
CN (1) CN111035849B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7038679B2 (ja) * 2019-03-05 2022-03-18 富士フイルム株式会社 熱可塑性樹脂原版の作製方法、金型の作製方法、モールドの作製方法及びパターンシートの製造方法
CN112569465B (zh) * 2020-12-29 2022-07-19 华东理工大学 一种微针贴片的制备方法
GB2622416B (en) * 2022-09-15 2025-04-02 Ndm Tech Ltd Skin preparation device

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS541061B2 (enExample) 1973-03-14 1979-01-19
US7497980B2 (en) 2003-11-10 2009-03-03 Agency For Science, Technology And Research Microneedles and microneedle fabrication
JP3945716B2 (ja) * 2005-12-14 2007-07-18 インターナショナル・ビジネス・マシーンズ・コーポレーション エンドミルとその製造方法
EP2047882B1 (en) * 2006-07-27 2014-09-10 Toppan Printing Co., Ltd. Microneedle and method for producing microneedle
JP2008114345A (ja) * 2006-11-07 2008-05-22 Toppan Printing Co Ltd 微細で鋭利な針状構造の規則配列体、及びその複製物の製造方法
JP2008237673A (ja) 2007-03-28 2008-10-09 Toppan Printing Co Ltd 針状体およびその製造方法
JP5401061B2 (ja) * 2008-09-04 2014-01-29 凸版印刷株式会社 針状体製造方法、および研削刃
JP5568324B2 (ja) * 2010-01-15 2014-08-06 凸版印刷株式会社 マイクロニードル製造方法
US20130096532A1 (en) * 2011-10-17 2013-04-18 Rutgers, The State University Of New Jersey Polymer-Based Micro-Needle Array Designs, Fabrication Processes, and Methods of Use Thereof for Drug Delivery
JP6662296B2 (ja) * 2014-11-07 2020-03-11 凸版印刷株式会社 経皮投薬用針集成体及びその製造方法
JP6482323B2 (ja) * 2015-03-03 2019-03-13 富士フイルム株式会社 経皮吸収シート
KR102074603B1 (ko) * 2015-09-30 2020-02-06 후지필름 가부시키가이샤 몰드의 제작 방법, 패턴 시트의 제조 방법, 전주 금형의 제작 방법, 및 전주 금형을 이용한 몰드의 제작 방법
JP6587345B2 (ja) * 2015-10-06 2019-10-09 富士フイルム株式会社 樹脂製モールドの作製方法
JP6533189B2 (ja) * 2016-05-24 2019-06-19 富士フイルム株式会社 パターンアレイシート成形用型の製造方法、及びマイクロニードルアレイの製造方法
JP2018042677A (ja) * 2016-09-13 2018-03-22 富士フイルム株式会社 凹状パターンモールドおよびパターンシートの製造方法

Also Published As

Publication number Publication date
CN111035849B (zh) 2023-03-28
US11597122B2 (en) 2023-03-07
EP3646919B1 (en) 2020-12-16
JP2020062078A (ja) 2020-04-23
EP3646919A1 (en) 2020-05-06
CN111035849A (zh) 2020-04-21
US20200114547A1 (en) 2020-04-16

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