JP6975641B2 - アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法 - Google Patents

アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法 Download PDF

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JP6975641B2
JP6975641B2 JP2017553347A JP2017553347A JP6975641B2 JP 6975641 B2 JP6975641 B2 JP 6975641B2 JP 2017553347 A JP2017553347 A JP 2017553347A JP 2017553347 A JP2017553347 A JP 2017553347A JP 6975641 B2 JP6975641 B2 JP 6975641B2
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angptl3
dsrna
pat
irna
expression
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JP2018512155A (ja
JP2018512155A5 (enExample
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ウィリアム・クアーベス
ケビン・フィッツジェラルド
ジェイムズ・バトラー
ステファニー・ウィリアムズ
グレゴリー・ヒンクル
マルティン・マイアー
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Alnylam Pharmaceuticals Inc
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JP2017553347A 2015-04-13 2016-04-13 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法 Active JP6975641B2 (ja)

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Application Number Priority Date Filing Date Title
JP2021147698A JP7817806B2 (ja) 2015-04-13 2021-09-10 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法
JP2023169168A JP2024009838A (ja) 2015-04-13 2023-09-29 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562146604P 2015-04-13 2015-04-13
US62/146,604 2015-04-13
US201562261361P 2015-12-01 2015-12-01
US62/261,361 2015-12-01
PCT/US2016/027271 WO2016168286A1 (en) 2015-04-13 2016-04-13 Angiopoietin-like 3 (angptl3) irna compositions and methods of use thereof

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JP2018512155A JP2018512155A (ja) 2018-05-17
JP2018512155A5 JP2018512155A5 (enExample) 2019-05-23
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JP2021147698A Active JP7817806B2 (ja) 2015-04-13 2021-09-10 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法
JP2023169168A Pending JP2024009838A (ja) 2015-04-13 2023-09-29 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法

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JP2023169168A Pending JP2024009838A (ja) 2015-04-13 2023-09-29 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法

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US (4) US10570393B2 (enExample)
EP (1) EP3283631A1 (enExample)
JP (3) JP6975641B2 (enExample)
KR (2) KR20250005546A (enExample)
CN (2) CN107743522B (enExample)
AU (2) AU2016247922B2 (enExample)
BR (1) BR112017021053A2 (enExample)
CA (1) CA2982450A1 (enExample)
EA (1) EA201792263A1 (enExample)
IL (3) IL295159B1 (enExample)
MX (2) MX392757B (enExample)
TW (3) TW202507005A (enExample)
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KR20250107294A (ko) 2017-12-01 2025-07-11 쑤저우 리보 라이프 사이언스 컴퍼니, 리미티드 핵산, 이를 포함하는 조성물과 컨쥬게이트, 및 그의 제조 방법과 용도
WO2019105418A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 双链寡核苷酸、含双链寡核苷酸的组合物与缀合物及制备方法和用途
WO2019105419A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
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TWI851574B (zh) * 2018-05-14 2024-08-11 美商阿尼拉製藥公司 血管收縮素原（ＡＧＴ）ｉＲＮＡ組成物及其使用方法
EP3842534A4 (en) 2018-08-21 2022-07-06 Suzhou Ribo Life Science Co., Ltd. NUCLEIC ACID, PHARMACEUTICAL COMPOSITION AND CONJUGATE WITH NUCLEIC ACID AND THEIR USE
WO2020063198A1 (zh) 2018-09-30 2020-04-02 苏州瑞博生物技术有限公司 一种siRNA缀合物及其制备方法和用途
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JP7507495B2 (ja) 2018-12-28 2024-06-28 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
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JP7610849B2 (ja) 2019-05-24 2025-01-09 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、薬物組成物及び複合体ならびに調製方法と使用
JP2023514000A (ja) * 2019-12-09 2023-04-05 エンピリコ インク． アンジオポエチン様４（ａｎｇｐｔｌ４）関連疾患の処置のためのオリゴヌクレオチド
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CN116887842A (zh) * 2020-10-16 2023-10-13 赛诺菲 用于抑制angptl3的新型rna组合物和方法
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