JP6966667B2 - ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 - Google Patents

ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 Download PDF

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Publication number
JP6966667B2
JP6966667B2 JP2021521065A JP2021521065A JP6966667B2 JP 6966667 B2 JP6966667 B2 JP 6966667B2 JP 2021521065 A JP2021521065 A JP 2021521065A JP 2021521065 A JP2021521065 A JP 2021521065A JP 6966667 B2 JP6966667 B2 JP 6966667B2
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Prior art keywords
aqueous ophthalmic
ophthalmic composition
diquafosol
polyvinylpyrrolidone
eye
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Japanese (ja)
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JPWO2021039748A1 (ja
Inventor
健司 森島
博之 浅田
雄介 桃川
明日香 神村
健一 遠藤
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Santen Pharmaceutical Co Ltd
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Santen Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2021521065A 2019-08-27 2020-08-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物 Active JP6966667B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021171358A JP2022003099A (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019154525 2019-08-27
JP2019154525 2019-08-27
PCT/JP2020/031917 WO2021039748A1 (fr) 2019-08-27 2020-08-25 Diquafosol ou sel correspondant et composition ophtalmique aqueuse contenant de la polyvinylpyrrolidone

Related Child Applications (1)

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JP2021171358A Division JP2022003099A (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

Publications (2)

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JPWO2021039748A1 JPWO2021039748A1 (ja) 2021-09-30
JP6966667B2 true JP6966667B2 (ja) 2021-11-17

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JP2021521065A Active JP6966667B2 (ja) 2019-08-27 2020-08-25 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物
JP2021171358A Pending JP2022003099A (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

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JP2021171358A Pending JP2022003099A (ja) 2019-08-27 2021-10-20 ジクアホソルまたはその塩、およびポリビニルピロリドンを含有する水性眼科用組成物

Country Status (5)

Country Link
JP (2) JP6966667B2 (fr)
KR (2) KR102656181B1 (fr)
CN (2) CN114286670B (fr)
TW (1) TWI848171B (fr)
WO (1) WO2021039748A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240180827A1 (en) * 2021-03-30 2024-06-06 Senju Pharmaceutical Co., Ltd. Suspension containing heterocyclidene acetamide derivative
CN114646705A (zh) * 2022-03-22 2022-06-21 武汉绿合医药科技有限公司 一种地夸磷索钠滴眼液有关物质含量检测方法
JP7245383B1 (ja) 2022-09-20 2023-03-23 参天製薬株式会社 ジクアホソルまたはその塩を含有する眼科用組成物のpHの低下を抑制する方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
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JPH0365270A (ja) 1989-07-31 1991-03-20 Kanzaki Paper Mfg Co Ltd 塗布シートの製造方法
JPH0365270U (fr) 1989-10-31 1991-06-25
US5358706A (en) * 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
CA2125060C (fr) * 1993-07-02 1999-03-30 Henry P. Dabrowski Solution ophtalmique pour larmes artificielles
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
KR100549904B1 (ko) * 1996-03-27 2006-05-16 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 우리딘트리포스페이트및관련화합물을함유하는섬모운동장해치료용약학조성물
US5900407A (en) * 1997-02-06 1999-05-04 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with uridine triphosphates and related compounds
US6274626B1 (en) * 1998-12-22 2001-08-14 Bausch & Lomb Incorporated Pheniramine-containing compositions and method for treating allergic responses
EP1245233A4 (fr) * 1999-12-27 2006-03-15 Santen Pharmaceutical Co Ltd Systeme permettant de stabiliser la couche de fluide lacrymal
BR0111297A (pt) * 2000-05-30 2004-01-06 Santen Pharmaceutical Co Ltd Promotor de migração epitelial corneana
CN103933614B (zh) * 2005-02-14 2016-03-02 庄臣及庄臣视力保护公司 舒适的眼用器件及其制造方法
EP2614838B1 (fr) * 2010-09-10 2016-04-20 Santen Pharmaceutical Co., Ltd. Diquafosol et l'acide hyaluronique ou ses sels pour le traitement de l'oeil sec
EA027736B1 (ru) * 2010-12-28 2017-08-31 Сантен Фармасьютикал Ко., Лтд. Глазной раствор, содержащий диквафозол, способ его получения и способ ингибирования образования нерастворимого осадка
KR20120077080A (ko) 2010-12-30 2012-07-10 동우 화인켐 주식회사 광학필름 및 이를 이용한 백라이트 유닛
US20160213708A1 (en) * 2012-01-08 2016-07-28 Medicure Technologies Ltd. Ophthalmic composition
JP5625081B2 (ja) * 2012-03-26 2014-11-12 参天製薬株式会社 ジクアホソル含有点眼液
JP2015032653A (ja) 2013-08-01 2015-02-16 株式会社東芝 固体撮像装置
JP6267003B2 (ja) 2014-02-27 2018-01-24 参天製薬株式会社 ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤
LT3139903T (lt) * 2014-05-07 2019-09-10 Croma-Pharma Gesellschaft M.B.H. Vandeninis akių tirpalas ir sausų akių sindromo gydymo būdas
MY182507A (en) * 2014-12-25 2021-01-25 Santen Pharmaceutical Co Ltd Aqueous ophthalmic solution
TW201707710A (zh) * 2015-06-05 2017-03-01 參天製藥股份有限公司 特徵爲用於滴入戴著軟性隱形眼鏡的乾眼症患者的眼睛之乾眼症治療劑
WO2019168023A1 (fr) * 2018-02-28 2019-09-06 参天製薬株式会社 Composition ophtalmique comprenant du diquafosol et un polymère cationique

Also Published As

Publication number Publication date
KR102656181B1 (ko) 2024-04-08
CN114286670A (zh) 2022-04-05
WO2021039748A1 (fr) 2021-03-04
CN117771172A (zh) 2024-03-29
KR20220052971A (ko) 2022-04-28
JP2022003099A (ja) 2022-01-11
TW202122094A (zh) 2021-06-16
CN114286670B (zh) 2024-01-16
JPWO2021039748A1 (ja) 2021-09-30
KR20240049646A (ko) 2024-04-16
TWI848171B (zh) 2024-07-11

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