JP6942789B2 - Ｃｈｒｉｍｓｏｎを用いた光遺伝学的視覚回復 - Google Patents

Ｃｈｒｉｍｓｏｎを用いた光遺伝学的視覚回復 Download PDF

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JP6942789B2
JP6942789B2 JP2019508309A JP2019508309A JP6942789B2 JP 6942789 B2 JP6942789 B2 JP 6942789B2 JP 2019508309 A JP2019508309 A JP 2019508309A JP 2019508309 A JP2019508309 A JP 2019508309A JP 6942789 B2 JP6942789 B2 JP 6942789B2
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protein
chrimson
tdt
cells
fused
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JP2019518073A5 (enExample
JP2019518073A (ja
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ディディエ プリュノー
ディディエ プリュノー
アンヌ ドゥアール
アンヌ ドゥアール
デニズ ダルカラ
デニズ ダルカラ
イェンス ドゥーベル
イェンス ドゥーベル
ロマン キャプレット
ロマン キャプレット
グレゴリー ゴーヴァン
グレゴリー ゴーヴァン
メリッサ デロシアーズ
メリッサ デロシアーズ
ホセ サヘル
ホセ サヘル
セルジュ ピコー
セルジュ ピコー
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Centre National de la Recherche Scientifique CNRS
Sorbonne Universite
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Sorbonne Universite
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JP2019508309A 2016-04-29 2017-04-28 Ｃｈｒｉｍｓｏｎを用いた光遺伝学的視覚回復 Active JP6942789B2 (ja)

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US201662329692P 2016-04-29 2016-04-29
US62/329,692 2016-04-29
PCT/IB2017/000663 WO2017187272A1 (en) 2016-04-29 2017-04-28 Optogenetic visual restoration using chrimson

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JP2019518073A JP2019518073A (ja) 2019-06-27
JP2019518073A5 JP2019518073A5 (enExample) 2020-05-07
JP6942789B2 true JP6942789B2 (ja) 2021-09-29

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US (2) US20190269755A1 (enExample)
EP (1) EP3448411A1 (enExample)
JP (1) JP6942789B2 (enExample)
KR (1) KR102466887B1 (enExample)
CN (1) CN110267673B (enExample)
AU (2) AU2017256910B2 (enExample)
CA (1) CA3025975A1 (enExample)
WO (1) WO2017187272A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190126043A1 (en) 2016-04-14 2019-05-02 The Trustees Of The University Of Pennsylvania Implantable living electrodes and methods for use thereof
EP3693061A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using filtering and associated devices
EP3693060A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using a command law for the radiant power of a light source and associated devices
EP3733139A1 (en) 2019-05-02 2020-11-04 Gensight Biologics Viewing apparatus and method for projecting a light signal
US20220249864A1 (en) * 2019-12-26 2022-08-11 Korea University Research And Business Foundation Method by which brain with alzheimer's disease recovers from brain wave damage by using optogenetics
US20250235585A1 (en) * 2022-02-18 2025-07-24 The Trustees Of The University Of Pennsylvania Tissue Engineered Spinal Tracts For Functional Regeneration After Spinal Cord Injury
WO2024033837A1 (en) 2022-08-11 2024-02-15 Institute Of Molecular And Clinical Ophthalmology Basel (Iob) Human cone photoreceptor optogenetic constructs
CN119827471B (zh) * 2025-02-14 2025-10-03 中山大学中山眼科中心 一种体内追踪外段蛋白运输的方法

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
US20070053996A1 (en) 2005-07-22 2007-03-08 Boyden Edward S Light-activated cation channel and uses thereof
US8470790B2 (en) * 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
EP1891976A1 (en) 2006-08-23 2008-02-27 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research Use of light sensitive genes
AU2009212309B2 (en) * 2008-02-07 2014-04-03 Ceregene, Inc. Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein
JP2011516091A (ja) 2008-04-18 2011-05-26 ノバルティス・フォルシュングスシュティフトゥング・ツヴァイクニーダーラッスング・フリードリッヒ・ミーシェー・インスティトゥート・フォー・バイオメディカル・リサーチ 失明の治療のための新規な治療用ツールおよび方法
RS66184B1 (sr) 2011-04-22 2024-12-31 Univ California Adeno-povezani virioni virusa sa varijantama kapsida i postupci za njihovu primenu
KR102084803B1 (ko) * 2011-11-12 2020-03-05 메사추세츠 인스티튜트 오브 테크놀로지 세포의 광학 조절을 위한 채널로돕신
WO2015161308A1 (en) * 2014-04-18 2015-10-22 Massachusetts Institute Of Technology Mutant channelrhodopsins with altered ion selectivity
US10882892B2 (en) * 2014-08-05 2021-01-05 Massachusetts Institute Of Technology Channelrhodopsin variants and uses thereof
US11390866B2 (en) * 2015-12-04 2022-07-19 Sorbonne Université Promoters and uses thereof

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Publication number Publication date
CN110267673A (zh) 2019-09-20
WO2017187272A1 (en) 2017-11-02
AU2017256910A1 (en) 2018-11-22
AU2022204884A1 (en) 2022-07-28
CA3025975A1 (en) 2017-11-02
AU2017256910B2 (en) 2022-04-07
KR102466887B1 (ko) 2022-11-11
JP2019518073A (ja) 2019-06-27
KR20190058383A (ko) 2019-05-29
EP3448411A1 (en) 2019-03-06
US20240165198A1 (en) 2024-05-23
CN110267673B (zh) 2023-05-16
US20190269755A1 (en) 2019-09-05
WO2017187272A8 (en) 2018-12-13

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