KR102466887B1 - Chrimson을 사용한 광유전학적 시력 회복 - Google Patents

Chrimson을 사용한 광유전학적 시력 회복 Download PDF

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KR102466887B1
KR102466887B1 KR1020187034650A KR20187034650A KR102466887B1 KR 102466887 B1 KR102466887 B1 KR 102466887B1 KR 1020187034650 A KR1020187034650 A KR 1020187034650A KR 20187034650 A KR20187034650 A KR 20187034650A KR 102466887 B1 KR102466887 B1 KR 102466887B1
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protein
chrimson
light
gly
cells
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KR20190058383A (ko
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디디에흐 프뤼노
안네 두아흐
데니츠 달카라
젠 뒤벨
로맹 캐플릿
그레고리 가뱅
멜리사 데로지에
조제 사헬
세흐게 피카우드
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젠사이트 바이올로직스
쏘흐본느 유니베흐시테
상뜨르 나쇼날 드 라 러쉐르쉬 샹띠피끄
인스티튜트 내셔널 드 라 싼테 에 드 라 리셰르셰 메디칼르 (인 썸)
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KR1020187034650A 2016-04-29 2017-04-28 Chrimson을 사용한 광유전학적 시력 회복 Active KR102466887B1 (ko)

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US201662329692P 2016-04-29 2016-04-29
US62/329,692 2016-04-29
PCT/IB2017/000663 WO2017187272A1 (en) 2016-04-29 2017-04-28 Optogenetic visual restoration using chrimson

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KR20190058383A KR20190058383A (ko) 2019-05-29
KR102466887B1 true KR102466887B1 (ko) 2022-11-11

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US (2) US20190269755A1 (enExample)
EP (1) EP3448411A1 (enExample)
JP (1) JP6942789B2 (enExample)
KR (1) KR102466887B1 (enExample)
CN (1) CN110267673B (enExample)
AU (2) AU2017256910B2 (enExample)
CA (1) CA3025975A1 (enExample)
WO (1) WO2017187272A1 (enExample)

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Publication number Priority date Publication date Assignee Title
US20190126043A1 (en) 2016-04-14 2019-05-02 The Trustees Of The University Of Pennsylvania Implantable living electrodes and methods for use thereof
EP3693061A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using filtering and associated devices
EP3693060A1 (en) 2019-02-05 2020-08-12 Gensight Biologics Method for controlling an optogenetic device using a command law for the radiant power of a light source and associated devices
EP3733139A1 (en) 2019-05-02 2020-11-04 Gensight Biologics Viewing apparatus and method for projecting a light signal
US20220249864A1 (en) * 2019-12-26 2022-08-11 Korea University Research And Business Foundation Method by which brain with alzheimer's disease recovers from brain wave damage by using optogenetics
US20250235585A1 (en) * 2022-02-18 2025-07-24 The Trustees Of The University Of Pennsylvania Tissue Engineered Spinal Tracts For Functional Regeneration After Spinal Cord Injury
WO2024033837A1 (en) 2022-08-11 2024-02-15 Institute Of Molecular And Clinical Ophthalmology Basel (Iob) Human cone photoreceptor optogenetic constructs
CN119827471B (zh) * 2025-02-14 2025-10-03 中山大学中山眼科中心 一种体内追踪外段蛋白运输的方法

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DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
US20070053996A1 (en) 2005-07-22 2007-03-08 Boyden Edward S Light-activated cation channel and uses thereof
US8470790B2 (en) * 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
EP1891976A1 (en) 2006-08-23 2008-02-27 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research Use of light sensitive genes
AU2009212309B2 (en) * 2008-02-07 2014-04-03 Ceregene, Inc. Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein
JP2011516091A (ja) 2008-04-18 2011-05-26 ノバルティス・フォルシュングスシュティフトゥング・ツヴァイクニーダーラッスング・フリードリッヒ・ミーシェー・インスティトゥート・フォー・バイオメディカル・リサーチ 失明の治療のための新規な治療用ツールおよび方法
RS66184B1 (sr) 2011-04-22 2024-12-31 Univ California Adeno-povezani virioni virusa sa varijantama kapsida i postupci za njihovu primenu
KR102084803B1 (ko) * 2011-11-12 2020-03-05 메사추세츠 인스티튜트 오브 테크놀로지 세포의 광학 조절을 위한 채널로돕신
WO2015161308A1 (en) * 2014-04-18 2015-10-22 Massachusetts Institute Of Technology Mutant channelrhodopsins with altered ion selectivity
US10882892B2 (en) * 2014-08-05 2021-01-05 Massachusetts Institute Of Technology Channelrhodopsin variants and uses thereof
US11390866B2 (en) * 2015-12-04 2022-07-19 Sorbonne Université Promoters and uses thereof

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Title
Duebel et al. "Optogenetics." Current opinion in ophthalmology. vol. 26,3 (2015): 226-32.*

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CN110267673A (zh) 2019-09-20
WO2017187272A1 (en) 2017-11-02
AU2017256910A1 (en) 2018-11-22
AU2022204884A1 (en) 2022-07-28
CA3025975A1 (en) 2017-11-02
AU2017256910B2 (en) 2022-04-07
JP2019518073A (ja) 2019-06-27
KR20190058383A (ko) 2019-05-29
JP6942789B2 (ja) 2021-09-29
EP3448411A1 (en) 2019-03-06
US20240165198A1 (en) 2024-05-23
CN110267673B (zh) 2023-05-16
US20190269755A1 (en) 2019-09-05
WO2017187272A8 (en) 2018-12-13

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