JP6933858B2 - 類縁アレルを検出可能な多重核酸アッセイ法およびその試薬 - Google Patents

類縁アレルを検出可能な多重核酸アッセイ法およびその試薬 Download PDF

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JP6933858B2
JP6933858B2 JP2018552172A JP2018552172A JP6933858B2 JP 6933858 B2 JP6933858 B2 JP 6933858B2 JP 2018552172 A JP2018552172 A JP 2018552172A JP 2018552172 A JP2018552172 A JP 2018552172A JP 6933858 B2 JP6933858 B2 JP 6933858B2
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dna
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JP2019510501A (ja
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エー．イー． マラス，サルヴァトーレ
エー．イー． マラス，サルヴァトーレ
ヴァーガス−ゴールド，ダイアナ
ティアギ，サンジェイ
ラッセル クレイマー，フレッド
ラッセル クレイマー，フレッド
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Rutgers State University of New Jersey
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    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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JP2018552172A 2016-04-07 2017-04-05 類縁アレルを検出可能な多重核酸アッセイ法およびその試薬 Active JP6933858B2 (ja)

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US201662319332P 2016-04-07 2016-04-07
US62/319,332 2016-04-07
PCT/US2017/026088 WO2017176852A1 (en) 2016-04-07 2017-04-05 Multiplex nucleic acid assay methods capable of detecting closely related alleles, and reagents therefor

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JP2019510501A JP2019510501A (ja) 2019-04-18
JP2019510501A5 JP2019510501A5 (enExample) 2020-07-09
JP6933858B2 true JP6933858B2 (ja) 2021-09-08

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US (1) US11542547B2 (enExample)
EP (1) EP3440226B1 (enExample)
JP (1) JP6933858B2 (enExample)
CN (1) CN109312398B (enExample)
AU (1) AU2017246663B2 (enExample)
CA (1) CA3020165A1 (enExample)
NZ (1) NZ748011A (enExample)
SG (1) SG11201808740TA (enExample)
WO (1) WO2017176852A1 (enExample)
ZA (1) ZA201807405B (enExample)

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US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
CA2824387C (en) 2011-02-09 2019-09-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
US20180173846A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
EP4428863A3 (en) 2015-05-11 2024-12-11 Natera, Inc. Methods and compositions for determining ploidy
DK3443119T3 (da) 2016-04-15 2022-05-23 Natera Inc Fremgangsmåde til bestemmelse af lunge cancer
GB201618485D0 (en) 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence
US12084720B2 (en) 2017-12-14 2024-09-10 Natera, Inc. Assessing graft suitability for transplantation
CA3088891A1 (en) * 2018-01-12 2019-07-18 Natera, Inc. Novel primers and uses thereof
JP7573443B2 (ja) 2018-04-14 2024-10-25 ナテラ， インコーポレイテッド 循環腫瘍ｄｎａの個別化された検出を用いる癌検出およびモニタリングの方法
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
CA3292164A1 (en) * 2018-09-25 2025-11-29 Co Diagnostics Inc Allele-specific design of cooperative primers for improved nucleic acid variant genotyping
CN110964814B (zh) * 2018-09-30 2024-05-03 迈克生物股份有限公司 用于核酸序列变异检测的引物、组合物及方法
CN111349691B (zh) * 2018-12-21 2023-10-20 迈克生物股份有限公司 Egfr基因缺失突变检测用组合物、试剂盒及检测方法
CN110541033B (zh) * 2019-09-27 2023-11-14 迈克生物股份有限公司 Egfr基因突变检测用组合物及检测方法
CN110592215A (zh) * 2019-09-27 2019-12-20 迈克生物股份有限公司 检测核酸序列的组合物及检测方法
IL291819A (en) 2019-10-02 2022-06-01 Univ Rutgers Assay methods and kits for detecting rare sequence variants
CN112824535B (zh) * 2019-11-21 2023-07-04 迈克生物股份有限公司 基因突变多重检测用引物组合物及其试剂盒
CN116121358B (zh) * 2022-11-11 2024-07-23 重庆浦济生命科技有限公司 用于精神药物基因检测的组合物、试剂盒及使用方法
EP4488384A1 (en) 2023-07-05 2025-01-08 Infiniplex Ltd. Primers for selective amplification of rare target sequences

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7198897B2 (en) 2001-12-19 2007-04-03 Brandeis University Late-PCR
US20060141518A1 (en) * 2004-03-24 2006-06-29 Lao Kai Q Detection of gene expression
KR101433208B1 (ko) * 2006-12-13 2014-08-22 루미넥스 코포레이션 실시간으로 ｐｃｒ의 다중 분석을 위한 시스템과 방법
SG11201506146TA (en) * 2013-02-07 2015-09-29 Univ Rutgers Highly selective nucleic acid amplification primers
WO2015038634A2 (en) * 2013-09-13 2015-03-19 Rutgers, The State University Of New Jersey Multiplex diagnostic assay for lyme disease and other tick-borne diseases
GB201409786D0 (en) * 2014-06-02 2014-07-16 Primer Design Ltd Nucleic acid amplification system
WO2016014921A1 (en) * 2014-07-24 2016-01-28 Brandies University Linear-expo-linear pcr (lel-pcr)

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EP3440226A1 (en) 2019-02-13
EP3440226B1 (en) 2021-02-17
JP2019510501A (ja) 2019-04-18
NZ748011A (en) 2025-05-02
CN109312398B (zh) 2022-05-31
CN109312398A (zh) 2019-02-05
AU2017246663B2 (en) 2022-09-01
ZA201807405B (en) 2021-04-28
SG11201808740TA (en) 2018-11-29
AU2017246663A1 (en) 2018-11-22
WO2017176852A1 (en) 2017-10-12
US11542547B2 (en) 2023-01-03
EP3440226A4 (en) 2019-11-13
US20190225999A1 (en) 2019-07-25
CA3020165A1 (en) 2017-10-12

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