JP6887948B2 - 親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法 - Google Patents

親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法 Download PDF

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JP6887948B2
JP6887948B2 JP2017534221A JP2017534221A JP6887948B2 JP 6887948 B2 JP6887948 B2 JP 6887948B2 JP 2017534221 A JP2017534221 A JP 2017534221A JP 2017534221 A JP2017534221 A JP 2017534221A JP 6887948 B2 JP6887948 B2 JP 6887948B2
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wnt
pulp
dentin
composition
lacz
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Japanese (ja)
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JP2018502094A (ja
JP2018502094A5 (enExample
Inventor
ジル ヘルムズ，
ジル ヘルムズ，
ダニエル ジェイ． ハンター，
ダニエル ジェイ． ハンター，
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/58—Preparations specially adapted for dental root treatment specially adapted for dental implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2017534221A 2014-12-29 2015-12-28 親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法 Expired - Fee Related JP6887948B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097502P 2014-12-29 2014-12-29
US62/097,502 2014-12-29
PCT/US2015/067683 WO2016109433A1 (en) 2014-12-29 2015-12-28 Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production

Publications (3)

Publication Number Publication Date
JP2018502094A JP2018502094A (ja) 2018-01-25
JP2018502094A5 JP2018502094A5 (enExample) 2019-05-30
JP6887948B2 true JP6887948B2 (ja) 2021-06-16

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JP2017534221A Expired - Fee Related JP6887948B2 (ja) 2014-12-29 2015-12-28 親油性薬剤を歯髄に送達するため、および象牙質生成を増強するための組成物および方法

Country Status (6)

Country Link
US (2) US10512668B2 (enExample)
EP (1) EP3240562B1 (enExample)
JP (1) JP6887948B2 (enExample)
AU (1) AU2015374240B2 (enExample)
CA (1) CA3009983A1 (enExample)
WO (1) WO2016109433A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201617820D0 (en) * 2016-10-21 2016-12-07 King S College London Dental treatment
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9554975B2 (en) 2005-03-21 2017-01-31 Glaxo Group Limited Alkyl sulfate free and orthophosphate free dentifrice composition comprising fluoride source and a silica dental abrasive
JP2010520286A (ja) 2007-03-05 2010-06-10 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ Ｗｎｔ組成物およびその使用方法
US20110171607A1 (en) 2007-10-25 2011-07-14 The Trustees Of Columbia University In The City Of New York Biopulp
TWI457141B (zh) * 2008-02-08 2014-10-21 Colgate Palmolive Co 雙組分口腔保健產品
US10391038B2 (en) * 2008-02-08 2019-08-27 Colgate-Palmolive Company Tooth sealant
EP2502985B1 (en) * 2009-11-17 2015-04-29 National University Corporation Okayama University Method for inducing differentiation of dental pulp cells into odontoblasts
WO2011063371A1 (en) 2009-11-23 2011-05-26 University Of Medicine And Dentistry Of New Jersey Dentinal drug delivery composition
EP2533764A4 (en) * 2010-02-08 2016-08-31 Univ Nebraska BIOMINERAL AND METAL BINDING LIPOSOME, THEIR SYNTHESIS AND METHOD FOR THE PRODUCTION THEREOF
WO2012034070A1 (en) 2010-09-09 2012-03-15 The Board Of Trustees Of The Leland Stanford Junior University Use of liposomal wnt compositions to enhance osseointegration
WO2012122081A2 (en) 2011-03-04 2012-09-13 President And Fellows Of Harvard College Dental treatment systems and uses thereof
CN105228557A (zh) 2013-03-21 2016-01-06 纽约市哥伦比亚大学理事会 用于牙组织再生的组合物和方法

Also Published As

Publication number Publication date
US11260103B2 (en) 2022-03-01
US10512668B2 (en) 2019-12-24
AU2015374240A1 (en) 2017-08-10
JP2018502094A (ja) 2018-01-25
EP3240562A1 (en) 2017-11-08
AU2015374240B2 (en) 2021-11-11
CA3009983A1 (en) 2016-07-07
US20200046801A1 (en) 2020-02-13
WO2016109433A1 (en) 2016-07-07
US20180000893A1 (en) 2018-01-04
EP3240562B1 (en) 2023-03-22
EP3240562A4 (en) 2018-08-15

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